STRINGSTRING
TP53INP2 TP53INP2 SVIP SVIP TBC1D5 TBC1D5 VPS39 VPS39 STX17 STX17 TRAPPC8 TRAPPC8 PLEKHM1 PLEKHM1 LAMP2 LAMP2 LOC102348211 LOC102348211 EPG5 EPG5 MFN2 MFN2 NBR1 NBR1 CHMP5 CHMP5 WDR81 WDR81 EPM2A EPM2A PJVK PJVK C5orf51 C5orf51 RAB23 RAB23 RIPK2 RIPK2 GABARAPL2 GABARAPL2 STING1 STING1 ATG4B ATG4B CLN3 CLN3 UVRAG UVRAG ATG7 ATG7 H3A1S1_LATCH H3A1S1_LATCH WDR45B WDR45B VAMP8 VAMP8 EMC6 EMC6 RAB43 RAB43 WDFY3 WDFY3 LIX1 LIX1 ULK2 ULK2 UBXN6 UBXN6 ULK3 ULK3 UBXN2A UBXN2A VPS16 VPS16 LOC102363169 LOC102363169 UFC1 UFC1 SNX14 SNX14 H3AFQ9_LATCH H3AFQ9_LATCH LOC102356960 LOC102356960 RB1CC1 RB1CC1 SNAPIN SNAPIN WIPI2 WIPI2 MAP1LC3C MAP1LC3C PACS2 PACS2 TRAPPC8-2 TRAPPC8-2 UBXN2B UBXN2B RETREG3 RETREG3 LOC102352152 LOC102352152 UBA5 UBA5 WDR45 WDR45 UFL1 UFL1 ATG9B ATG9B H3AMM0_LATCH H3AMM0_LATCH SNAP29 SNAP29 ATG16L2 ATG16L2 SNX7 SNX7 PIK3R4 PIK3R4 NOD2 NOD2 RUBCNL RUBCNL MAP1LC3B MAP1LC3B RETREG2 RETREG2 AUP1 AUP1 H3AS24_LATCH H3AS24_LATCH PSEN1 PSEN1 BAG3 BAG3 NSFL1C NSFL1C VTI1A VTI1A LOC102349562 LOC102349562 ATG9A ATG9A SQSTM1 SQSTM1 SPG11 SPG11 VCP VCP RETREG1 RETREG1 ZFYVE1 ZFYVE1 TECPR1 TECPR1 OGT OGT RAB1B RAB1B ATG101 ATG101 RAB1A RAB1A PLAA PLAA ATG5 ATG5 VPS41 VPS41 RAB33B RAB33B ATG10 ATG10 TP53 TP53 LIX1L LIX1L H3B3L3_LATCH H3B3L3_LATCH SNX30 SNX30 NOD1 NOD1 RAB19 RAB19 CHMP6 CHMP6 TAZ TAZ RAB7A RAB7A ATP13A2 ATP13A2 LOC102365663 LOC102365663 MFSD8 MFSD8 PIK3C3 PIK3C3 WIPI1 WIPI1 TEX264 TEX264 EI24 EI24 ATG3 ATG3 ILRUN ILRUN KIAA1324 KIAA1324 TMEM41B TMEM41B ZFYVE26 ZFYVE26 PINK1 PINK1 VTI1B VTI1B TIGAR TIGAR ATG2A ATG2A H3BFJ3_LATCH H3BFJ3_LATCH ATG2B ATG2B ULK1 ULK1 AMBRA1 AMBRA1 LOC102357932 LOC102357932 ATG13 ATG13 YOD1 YOD1 ATG14 ATG14 MAP1LC3A MAP1LC3A UFM1 UFM1 VMP1 VMP1 GABARAPL1-2 GABARAPL1-2 M3XJQ7_LATCH M3XJQ7_LATCH LOC102348796 LOC102348796 ATG12 ATG12 BECN1 BECN1 DDRGK1 DDRGK1 GABARAPL1 GABARAPL1 TP53INP1 TP53INP1 PHB2 PHB2 H2ZSK8_LATCH H2ZSK8_LATCH ATG16L1 ATG16L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TP53INP2Tumor protein p53 inducible nuclear protein 2. (232 aa)
SVIPSi:ch73-147o17.1. (80 aa)
TBC1D5TBC1 domain family member 5. (335 aa)
VPS39VPS39 subunit of HOPS complex. (875 aa)
STX17Syntaxin 17. (308 aa)
TRAPPC8Uncharacterized protein. (498 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1054 aa)
LAMP2Lysosomal associated membrane protein 2. (416 aa)
LOC102348211ATG16 domain-containing protein. (243 aa)
EPG5Ectopic P-granules autophagy protein 5 homolog (C. elegans). (1395 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
NBR1NBR1 autophagy cargo receptor. (1005 aa)
CHMP5Charged multivesicular body protein 5. (220 aa)
WDR81WD repeat domain 81. (1916 aa)
EPM2AEPM2A glucan phosphatase, laforin. (228 aa)
PJVKPejvakin. (355 aa)
C5orf51Chromosome 5 open reading frame 51. (290 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (567 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
STING1Uncharacterized protein. (380 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (396 aa)
CLN3Battenin. (406 aa)
UVRAGUV radiation resistance associated. (407 aa)
ATG7Autophagy related 7. (593 aa)
H3A1S1_LATCHRUN domain-containing protein. (1123 aa)
WDR45BWD repeat domain 45B. (344 aa)
VAMP8Vesicle associated membrane protein 8. (104 aa)
EMC6ER membrane protein complex subunit 6. (112 aa)
RAB43RAB43, member RAS oncogene family. (213 aa)
WDFY3Uncharacterized protein. (854 aa)
LIX1Limb and CNS expressed 1. (282 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1040 aa)
UBXN6UBX domain protein 6. (439 aa)
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (471 aa)
UBXN2AUBX domain protein 2A. (254 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (823 aa)
LOC102363169Uncharacterized protein. (130 aa)
UFC1Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (169 aa)
SNX14Sorting nexin 14. (945 aa)
H3AFQ9_LATCHUncharacterized protein. (481 aa)
LOC102356960Charged multivesicular body protein 3. (220 aa)
RB1CC1RB1-inducible coiled-coil 1. (1296 aa)
SNAPINSNAP associated protein. (137 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (431 aa)
MAP1LC3CMicrotubule associated protein 1 light chain 3 gamma. (142 aa)
PACS2Phosphofurin acidic cluster sorting protein 2. (853 aa)
TRAPPC8-2Trafficking protein particle complex 8. (566 aa)
UBXN2BUBX domain protein 2B. (298 aa)
RETREG3Reticulophagy regulator family member 3. (465 aa)
LOC102352152Uncharacterized protein. (206 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (407 aa)
WDR45WD repeat domain 45. (360 aa)
UFL1UFM1 specific ligase 1. (792 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (801 aa)
H3AMM0_LATCHATG11 domain-containing protein. (241 aa)
SNAP29Synaptosome associated protein 29. (265 aa)
ATG16L2ATG16 autophagy related 16-like 2 (S. cerevisiae). (340 aa)
SNX7Sorting nexin 7. (426 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1363 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (854 aa)
RUBCNLRubicon like autophagy enhancer. (468 aa)
MAP1LC3BMicrotubule-associated protein 1 light chain 3 beta. (125 aa)
RETREG2Reticulophagy regulator family member 2. (538 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (423 aa)
H3AS24_LATCHUncharacterized protein. (270 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
BAG3BCL2 associated athanogene 3. (561 aa)
NSFL1CNSFL1 cofactor. (370 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (214 aa)
LOC102349562Prohibitin. (309 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (854 aa)
SQSTM1Sequestosome 1. (441 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2438 aa)
VCPValosin containing protein. (801 aa)
RETREG1Reticulophagy regulator 1. (458 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (782 aa)
TECPR1Tectonin beta-propeller repeat containing 1. (1158 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1048 aa)
RAB1BRAB1B, member RAS oncogene family. (203 aa)
ATG101Autophagy related 101. (218 aa)
RAB1ARAB1A, member RAS oncogene family. (229 aa)
PLAAPhospholipase A2 activating protein. (470 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (804 aa)
RAB33BRAB33B, member RAS oncogene family. (230 aa)
ATG10Autophagy related 10. (248 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
LIX1LLimb and CNS expressed 1 like. (345 aa)
H3B3L3_LATCHNACHT domain-containing protein. (837 aa)
SNX30Sorting nexin family member 30. (513 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (830 aa)
RAB19RAB19, member RAS oncogene family. (260 aa)
CHMP6Charged multivesicular body protein 6. (146 aa)
TAZTafazzin family protein; Belongs to the taffazin family. (264 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1091 aa)
LOC102365663Zgc:136908; Belongs to the AAA ATPase family. (697 aa)
MFSD8Major facilitator superfamily domain containing 8. (522 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (825 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (450 aa)
TEX264Testis expressed 264, ER-phagy receptor. (310 aa)
EI24EI24 autophagy associated transmembrane protein. (340 aa)
ATG3Autophagy-related protein 3. (314 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (286 aa)
KIAA1324KIAA1324. (825 aa)
TMEM41BTransmembrane protein 41B. (285 aa)
ZFYVE26Zinc finger FYVE-type containing 26. (2567 aa)
PINK1PTEN induced kinase 1. (467 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (235 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (212 aa)
ATG2AAutophagy related 2A. (1899 aa)
H3BFJ3_LATCHVPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
ATG2BAutophagy related 2B. (2085 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1046 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1195 aa)
LOC102357932Si:ch211-11n16.2. (535 aa)
ATG13Autophagy related 13. (554 aa)
YOD1YOD1 deubiquitinase. (304 aa)
ATG14Autophagy related 14. (499 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
UFM1Ubiquitin fold modifier 1. (74 aa)
VMP1Vacuole membrane protein 1. (406 aa)
GABARAPL1-2Uncharacterized protein. (117 aa)
M3XJQ7_LATCHCBM20 domain-containing protein. (180 aa)
LOC102348796Uncharacterized protein. (497 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (145 aa)
BECN1Beclin 1, autophagy related. (447 aa)
DDRGK1DDRGK domain containing 1. (243 aa)
GABARAPL1GABA type A receptor associated protein like 1. (87 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (240 aa)
PHB2Prohibitin. (305 aa)
H2ZSK8_LATCHTYR_PHOSPHATASE_2 domain-containing protein. (101 aa)
ATG16L1Autophagy related 16 like 1. (597 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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