(14 nodes) Calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CLDN5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
	LOC102362450	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (192 aa)
	CLDN16	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (255 aa)
	CLDN1	Claudin 1. (210 aa)
	CLDN12	Claudin 12. (247 aa)
	CLDN2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (238 aa)
	LOC102362746	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
	LOC102346705	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
	H3A9Z9_LATCH	Claudin 23a. (213 aa)
	H3A812_LATCH	Uncharacterized protein. (193 aa)
	LOC106705730	Uncharacterized protein. (200 aa)
	LOC102348536	Uncharacterized protein. (184 aa)
	LOC102348856	Uncharacterized protein. (190 aa)
	H2ZTR7_LATCH	Uncharacterized protein. (190 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN1	CLDN12	ENSLACP00000017569	ENSLACP00000016546	Claudin 1.	Claudin 12.	0.626
CLDN1	CLDN2	ENSLACP00000017569	ENSLACP00000014944	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.690
CLDN1	CLDN5	ENSLACP00000017569	ENSLACP00000017353	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.784
CLDN1	H3A812_LATCH	ENSLACP00000017569	ENSLACP00000005783	Claudin 1.	Uncharacterized protein.	0.748
CLDN1	H3A9Z9_LATCH	ENSLACP00000017569	ENSLACP00000006470	Claudin 1.	Claudin 23a.	0.710
CLDN1	LOC102346705	ENSLACP00000017569	ENSLACP00000013916	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.698
CLDN1	LOC102348536	ENSLACP00000017569	ENSLACP00000004957	Claudin 1.	Uncharacterized protein.	0.774
CLDN1	LOC102348856	ENSLACP00000017569	ENSLACP00000004079	Claudin 1.	Uncharacterized protein.	0.775
CLDN1	LOC102362450	ENSLACP00000017569	ENSLACP00000020610	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.746
CLDN1	LOC102362746	ENSLACP00000017569	ENSLACP00000014215	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.761
CLDN1	LOC106705730	ENSLACP00000017569	ENSLACP00000005246	Claudin 1.	Uncharacterized protein.	0.750
CLDN12	CLDN1	ENSLACP00000016546	ENSLACP00000017569	Claudin 12.	Claudin 1.	0.626
CLDN12	CLDN2	ENSLACP00000016546	ENSLACP00000014944	Claudin 12.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.614
CLDN12	CLDN5	ENSLACP00000016546	ENSLACP00000017353	Claudin 12.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.613
CLDN12	LOC106705730	ENSLACP00000016546	ENSLACP00000005246	Claudin 12.	Uncharacterized protein.	0.573
CLDN16	CLDN5	ENSLACP00000018273	ENSLACP00000017353	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.554
CLDN16	H3A9Z9_LATCH	ENSLACP00000018273	ENSLACP00000006470	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin 23a.	0.439
CLDN2	CLDN1	ENSLACP00000014944	ENSLACP00000017569	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin 1.	0.690
CLDN2	CLDN12	ENSLACP00000014944	ENSLACP00000016546	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin 12.	0.614
CLDN2	CLDN5	ENSLACP00000014944	ENSLACP00000017353	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.729