(13 nodes) Somatic hypermutation of immunoglobulin genes network (Latimeria chalumnae)

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second shell of interactors

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Known Interactions

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Predicted Interactions

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Your Input:
	MSH6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa)
	EXO1	Exonuclease 1. (805 aa)
	SAMHD1	Uncharacterized protein. (621 aa)
	PMS2	PMS1 homolog 2, mismatch repair system component. (872 aa)
	LOC102360187	MutS homolog 2 (E. coli). (447 aa)
	H2ZX83_LATCH	MutS homolog 2 (E. coli). (360 aa)
	MLH1	MutL homolog 1. (821 aa)
	H3ALC0_LATCH	Uncharacterized protein. (630 aa)
	AICDA	Activation-induced cytidine deaminase. (149 aa)
	LOC102354087	SAM domain and HD domain 1. (617 aa)
	MCM3AP	Minichromosome maintenance complex component 3 associated protein. (1957 aa)
	UNG	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (315 aa)
	POLB	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AICDA	MSH6	ENSLACP00000010577	ENSLACP00000017187	Activation-induced cytidine deaminase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.418
AICDA	UNG	ENSLACP00000010577	ENSLACP00000014193	Activation-induced cytidine deaminase.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.665
EXO1	H2ZX83_LATCH	ENSLACP00000019411	ENSLACP00000002004	Exonuclease 1.	MutS homolog 2 (E. coli).	0.973
EXO1	LOC102360187	ENSLACP00000019411	ENSLACP00000000628	Exonuclease 1.	MutS homolog 2 (E. coli).	0.973
EXO1	MLH1	ENSLACP00000019411	ENSLACP00000008921	Exonuclease 1.	MutL homolog 1.	0.998
EXO1	MSH6	ENSLACP00000019411	ENSLACP00000017187	Exonuclease 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.995
EXO1	PMS2	ENSLACP00000019411	ENSLACP00000022793	Exonuclease 1.	PMS1 homolog 2, mismatch repair system component.	0.994
EXO1	POLB	ENSLACP00000019411	ENSLACP00000016610	Exonuclease 1.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.649
EXO1	SAMHD1	ENSLACP00000019411	ENSLACP00000020840	Exonuclease 1.	Uncharacterized protein.	0.495
EXO1	UNG	ENSLACP00000019411	ENSLACP00000014193	Exonuclease 1.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.605
H2ZX83_LATCH	EXO1	ENSLACP00000002004	ENSLACP00000019411	MutS homolog 2 (E. coli).	Exonuclease 1.	0.973
H2ZX83_LATCH	LOC102360187	ENSLACP00000002004	ENSLACP00000000628	MutS homolog 2 (E. coli).	MutS homolog 2 (E. coli).	0.989
H2ZX83_LATCH	MLH1	ENSLACP00000002004	ENSLACP00000008921	MutS homolog 2 (E. coli).	MutL homolog 1.	0.993
H2ZX83_LATCH	MSH6	ENSLACP00000002004	ENSLACP00000017187	MutS homolog 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.988
H2ZX83_LATCH	PMS2	ENSLACP00000002004	ENSLACP00000022793	MutS homolog 2 (E. coli).	PMS1 homolog 2, mismatch repair system component.	0.984
H2ZX83_LATCH	UNG	ENSLACP00000002004	ENSLACP00000014193	MutS homolog 2 (E. coli).	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.481
LOC102360187	EXO1	ENSLACP00000000628	ENSLACP00000019411	MutS homolog 2 (E. coli).	Exonuclease 1.	0.973
LOC102360187	H2ZX83_LATCH	ENSLACP00000000628	ENSLACP00000002004	MutS homolog 2 (E. coli).	MutS homolog 2 (E. coli).	0.989
LOC102360187	MLH1	ENSLACP00000000628	ENSLACP00000008921	MutS homolog 2 (E. coli).	MutL homolog 1.	0.995
LOC102360187	MSH6	ENSLACP00000000628	ENSLACP00000017187	MutS homolog 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.989