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ACVR1 ACVR1 CSNK2B CSNK2B LOC102348027 LOC102348027 H3A271_LATCH H3A271_LATCH CSNK2A2 CSNK2A2 DYRK2 DYRK2 TGFBR2 TGFBR2 WNK3 WNK3 TSSK4 TSSK4 CDC42BPB CDC42BPB H3ABK5_LATCH H3ABK5_LATCH LOC102353948 LOC102353948 GSK3A GSK3A TGFBR1 TGFBR1 TNKS TNKS DYRK3 DYRK3 CDK5 CDK5 H3AKB9_LATCH H3AKB9_LATCH STK39 STK39 CDC42BPA CDC42BPA H3AND1_LATCH H3AND1_LATCH GSK3B GSK3B STK11 STK11 LRRK2 LRRK2 H3AYA9_LATCH H3AYA9_LATCH H3B0H2_LATCH H3B0H2_LATCH PRKDC PRKDC ROCK1 ROCK1 CDK10 CDK10 DYRK1B DYRK1B HIPK1 HIPK1 ROCK2 ROCK2 KIAA1549 KIAA1549 H3B8U3_LATCH H3B8U3_LATCH DCAF1 DCAF1 MTOR MTOR CHEK1 CHEK1 HIPK3 HIPK3 NLK NLK VRK1 VRK1 DYRK4 DYRK4 ULK1 ULK1 ACVR1B ACVR1B DYRK1A DYRK1A CDK1 CDK1 TTK TTK LOC102356233 LOC102356233 HIPK4 HIPK4 PDPK1 PDPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (148 aa)
LOC102348027Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (401 aa)
H3A271_LATCHProtein kinase domain-containing protein. (394 aa)
CSNK2A2Casein kinase 2, alpha prime polypeptide b; Belongs to the protein kinase superfamily. (347 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (590 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
WNK3WNK lysine deficient protein kinase 3. (1769 aa)
TSSK4Testis specific serine kinase 4; Belongs to the protein kinase superfamily. (368 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1713 aa)
H3ABK5_LATCHProtein kinase domain-containing protein. (360 aa)
LOC102353948Nemo-like kinase, type 1. (336 aa)
GSK3AGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (463 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
TNKSPoly [ADP-ribose] polymerase. (1233 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (573 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
H3AKB9_LATCHUncharacterized protein. (498 aa)
STK39Serine/threonine kinase 39. (493 aa)
CDC42BPACDC42 binding protein kinase alpha. (881 aa)
H3AND1_LATCHUncharacterized protein. (239 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
LRRK2Leucine rich repeat kinase 2. (2508 aa)
H3AYA9_LATCHProtein kinase domain-containing protein. (357 aa)
H3B0H2_LATCHUncharacterized protein. (441 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4083 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1350 aa)
CDK10Cyclin dependent kinase 10. (366 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (684 aa)
HIPK1Homeodomain interacting protein kinase 1. (1225 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1462 aa)
KIAA1549Si:ch211-1e14.1. (1462 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1510 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (475 aa)
HIPK3Homeodomain interacting protein kinase 3. (1204 aa)
NLKMitogen-activated protein kinase. (382 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (480 aa)
DYRK4Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4. (615 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1046 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (489 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (765 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
TTKTTK protein kinase. (889 aa)
LOC102356233TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (574 aa)
HIPK4Homeodomain interacting protein kinase 4. (614 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (563 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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