(22 nodes) Peptide cross-linking network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102363384	Uncharacterized protein. (479 aa)
	THBS1	Thrombospondin 1. (1170 aa)
	H3BCX1_LATCH	Uncharacterized protein. (79 aa)
	SPOCK2	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (362 aa)
	LOC102366055	Uncharacterized protein. (579 aa)
	RNF113A	Ring finger protein 113A. (346 aa)
	TGM4	Transglutaminase 4. (687 aa)
	NDNF	Neuron derived neurotrophic factor. (571 aa)
	LOC102348144	Transglutaminase 2, like. (682 aa)
	TGM2	Transglutaminase 2. (620 aa)
	LOC102346566	Annexin. (343 aa)
	H3AGH2_LATCH	Neuron-derived neurotrophic factor, like. (567 aa)
	FN1	Fibronectin 1. (2295 aa)
	F13A1	Coagulation factor XIII A chain. (688 aa)
	LOC102355330	TGc domain-containing protein. (614 aa)
	LOC102367266	TGc domain-containing protein. (742 aa)
	MAMDC2	MAM domain containing 2. (421 aa)
	LOC102355065	TGc domain-containing protein. (762 aa)
	DCN	Decorin; May affect the rate of fibrils formation. (353 aa)
	EGFLAM	EGF like, fibronectin type III and laminin G domains. (587 aa)
	LOC102356571	MAM domain-containing protein. (190 aa)
	LOC102366992	Uncharacterized protein. (297 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCN	FN1	ENSLACP00000001330	ENSLACP00000005793	Decorin; May affect the rate of fibrils formation.	Fibronectin 1.	0.497
DCN	LOC102346566	ENSLACP00000001330	ENSLACP00000010172	Decorin; May affect the rate of fibrils formation.	Annexin.	0.404
DCN	THBS1	ENSLACP00000001330	ENSLACP00000020712	Decorin; May affect the rate of fibrils formation.	Thrombospondin 1.	0.554
F13A1	LOC102363384	ENSLACP00000005448	ENSLACP00000022159	Coagulation factor XIII A chain.	Uncharacterized protein.	0.641
FN1	DCN	ENSLACP00000005793	ENSLACP00000001330	Fibronectin 1.	Decorin; May affect the rate of fibrils formation.	0.497
LOC102346566	DCN	ENSLACP00000010172	ENSLACP00000001330	Annexin.	Decorin; May affect the rate of fibrils formation.	0.404
LOC102348144	LOC102363384	ENSLACP00000013730	ENSLACP00000022159	Transglutaminase 2, like.	Uncharacterized protein.	0.578
LOC102355065	LOC102363384	ENSLACP00000001370	ENSLACP00000022159	TGc domain-containing protein.	Uncharacterized protein.	0.641
LOC102355330	LOC102363384	ENSLACP00000003340	ENSLACP00000022159	TGc domain-containing protein.	Uncharacterized protein.	0.641
LOC102356571	MAMDC2	ENSLACP00000000820	ENSLACP00000001518	MAM domain-containing protein.	MAM domain containing 2.	0.900
LOC102363384	F13A1	ENSLACP00000022159	ENSLACP00000005448	Uncharacterized protein.	Coagulation factor XIII A chain.	0.641
LOC102363384	LOC102348144	ENSLACP00000022159	ENSLACP00000013730	Uncharacterized protein.	Transglutaminase 2, like.	0.578
LOC102363384	LOC102355065	ENSLACP00000022159	ENSLACP00000001370	Uncharacterized protein.	TGc domain-containing protein.	0.641
LOC102363384	LOC102355330	ENSLACP00000022159	ENSLACP00000003340	Uncharacterized protein.	TGc domain-containing protein.	0.641
LOC102363384	LOC102366992	ENSLACP00000022159	ENSLACP00000000798	Uncharacterized protein.	Uncharacterized protein.	0.641
LOC102363384	LOC102367266	ENSLACP00000022159	ENSLACP00000003022	Uncharacterized protein.	TGc domain-containing protein.	0.641
LOC102363384	TGM2	ENSLACP00000022159	ENSLACP00000011981	Uncharacterized protein.	Transglutaminase 2.	0.578
LOC102363384	TGM4	ENSLACP00000022159	ENSLACP00000014590	Uncharacterized protein.	Transglutaminase 4.	0.641
LOC102366992	LOC102363384	ENSLACP00000000798	ENSLACP00000022159	Uncharacterized protein.	Uncharacterized protein.	0.641
LOC102367266	LOC102363384	ENSLACP00000003022	ENSLACP00000022159	TGc domain-containing protein.	Uncharacterized protein.	0.641