STRINGSTRING
AKT1 AKT1 PRKCA PRKCA PAK2 PAK2 DCLK3 DCLK3 PLK1 PLK1 PARP2 PARP2 TGFBR2 TGFBR2 DYRK2 DYRK2 CAMK1D CAMK1D DGKQ DGKQ PKD1 PKD1 MAPK7 MAPK7 H3A3C0_LATCH H3A3C0_LATCH LOC102356269 LOC102356269 H3A2T6_LATCH H3A2T6_LATCH PRKAA1 PRKAA1 CSNK2A2 CSNK2A2 H3A271_LATCH H3A271_LATCH MAP3K12 MAP3K12 LOC102348027 LOC102348027 SMTNL1 SMTNL1 MYO3A MYO3A PRKCB PRKCB PARP1 PARP1 NTRK2 NTRK2 H2ZZW6_LATCH H2ZZW6_LATCH PDGFB PDGFB CAMKV CAMKV MAPK9 MAPK9 CAMK4 CAMK4 ULK2 ULK2 ULK3 ULK3 GALNT2 GALNT2 H2ZWB9_LATCH H2ZWB9_LATCH MASTL MASTL SGK2 SGK2 MAMDC2 MAMDC2 LOC102356451 LOC102356451 LOC102354262 LOC102354262 DCN DCN TTBK2 TTBK2 NEK7 NEK7 H2ZV04_LATCH H2ZV04_LATCH SGK1 SGK1 EGFLAM EGFLAM LOC102356571 LOC102356571 MAPK13 MAPK13 CHEK2 CHEK2 LOC102359041 LOC102359041 MAPKAPK5 MAPKAPK5 TLK1 TLK1 IKBKE IKBKE STK38L STK38L RPS6KA4 RPS6KA4 STK32B STK32B MAST2 MAST2 BRSK2 BRSK2 MGAT5B MGAT5B LATS1 LATS1 RIPK1 RIPK1 ATR ATR CDC7 CDC7 H3AND1_LATCH H3AND1_LATCH RPS6KA6 RPS6KA6 STK32C STK32C POGLUT2 POGLUT2 POGLUT3 POGLUT3 H3B6K7_LATCH H3B6K7_LATCH HIPK1 HIPK1 ROCK2 ROCK2 KIAA1549 KIAA1549 LOC102365238 LOC102365238 H3B8L2_LATCH H3B8L2_LATCH BAK1 BAK1 H3B8U3_LATCH H3B8U3_LATCH AURKA AURKA PRKCQ PRKCQ MTOR MTOR CLSPN CLSPN PBK PBK LOC102366055 LOC102366055 SPOCK2 SPOCK2 H3BCX1_LATCH H3BCX1_LATCH HIPK3 HIPK3 PINK1 PINK1 MAPKAPK3 MAPKAPK3 NLK NLK VRK1 VRK1 TOP1 TOP1 CSNK1A1 CSNK1A1 H3AJ82_LATCH H3AJ82_LATCH TSSK6 TSSK6 SMG1 SMG1 POGLUT1 POGLUT1 CDK5 CDK5 DYRK3 DYRK3 SGK3 SGK3 TNKS TNKS TTBK1 TTBK1 VRK2 VRK2 TLK2 TLK2 CSNK1E CSNK1E PRKX PRKX BRSK1 BRSK1 H3AGH2_LATCH H3AGH2_LATCH PRKCG PRKCG STK38 STK38 RPS6KA1 RPS6KA1 PKN2 PKN2 LOC102361574 LOC102361574 GALNT1 GALNT1 TGFBR1 TGFBR1 HPF1 HPF1 PDK3 PDK3 GSK3A GSK3A LOC102353948 LOC102353948 CHUK CHUK BAX BAX H3ABK5_LATCH H3ABK5_LATCH MAPKAPK2 MAPKAPK2 ILK ILK LOC102350595 LOC102350595 MAST3 MAST3 PRKAA2 PRKAA2 LOC102362603 LOC102362603 LOC102361440 LOC102361440 GSK3B GSK3B SYK SYK RPS6KA5 RPS6KA5 MKNK2 MKNK2 RPS6KB1 RPS6KB1 MAST1 MAST1 LRRK2 LRRK2 CSNK1G2 CSNK1G2 NDNF NDNF PRKCD PRKCD H3B0H2_LATCH H3B0H2_LATCH PIKFYVE PIKFYVE MAPK1 MAPK1 TBK1 TBK1 CSNK1D CSNK1D PRKDC PRKDC H3B277_LATCH H3B277_LATCH UHMK1 UHMK1 ROCK1 ROCK1 GAS6 GAS6 DCLK1 DCLK1 PRKCZ PRKCZ PRKCI PRKCI DYRK1B DYRK1B H3B4R6_LATCH H3B4R6_LATCH LOC102355470 LOC102355470 CSNK1G1 CSNK1G1 MKNK1 MKNK1 PKN1 PKN1 LATS2 LATS2 H3AKB9_LATCH H3AKB9_LATCH H3AKN9_LATCH H3AKN9_LATCH MORC3 MORC3 DYRK4 DYRK4 PRKCH PRKCH ULK1 ULK1 GALNT16 GALNT16 NEK6 NEK6 AKT2 AKT2 NTMT1 NTMT1 DYRK1A DYRK1A CDK1 CDK1 TTK TTK EIF2AK3 EIF2AK3 LOC102356233 LOC102356233 AKT3 AKT3 EPO EPO HIPK4 HIPK4 PDPK1 PDPK1 RICTOR RICTOR RPS6KA3 RPS6KA3 PRKCE PRKCE MYO3B MYO3B MAST4 MAST4 TSSK4 TSSK4 ATM ATM CAMK1 CAMK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (478 aa)
PRKCAProtein kinase C alpha; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (577 aa)
PAK2Non-specific serine/threonine protein kinase. (521 aa)
DCLK3Doublecortin like kinase 3. (769 aa)
PLK1Serine/threonine-protein kinase PLK. (595 aa)
PARP2Poly [ADP-ribose] polymerase. (502 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (590 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID. (180 aa)
DGKQDiacylglycerol kinase. (940 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4241 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (927 aa)
H3A3C0_LATCHUncharacterized protein. (176 aa)
LOC102356269Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
H3A2T6_LATCHProtein kinase domain-containing protein. (97 aa)
PRKAA1Non-specific serine/threonine protein kinase. (552 aa)
CSNK2A2Casein kinase 2, alpha prime polypeptide b; Belongs to the protein kinase superfamily. (347 aa)
H3A271_LATCHProtein kinase domain-containing protein. (394 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase. (904 aa)
LOC102348027Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (401 aa)
SMTNL1Calponin-homology (CH) domain-containing protein. (388 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (600 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (578 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
NTRK2Tyrosine-protein kinase receptor. (819 aa)
H2ZZW6_LATCHProtein kinase domain-containing protein. (513 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (209 aa)
CAMKVCaM kinase like vesicle associated. (397 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (373 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1040 aa)
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (471 aa)
GALNT2Polypeptide N-acetylgalactosaminyltransferase. (561 aa)
H2ZWB9_LATCHZgc:162297. (276 aa)
MASTLMicrotubule associated serine/threonine kinase like. (880 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (369 aa)
MAMDC2MAM domain containing 2. (421 aa)
LOC102356451Uncharacterized protein. (208 aa)
LOC102354262Mitogen-activated protein kinase. (330 aa)
DCNDecorin; May affect the rate of fibrils formation. (353 aa)
TTBK2Tau tubulin kinase 2. (1233 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
H2ZV04_LATCHAurora kinase B; Belongs to the protein kinase superfamily. (278 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (434 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (587 aa)
LOC102356571MAM domain-containing protein. (190 aa)
MAPK13Mitogen-activated protein kinase. (162 aa)
CHEK2Checkpoint kinase 2. (411 aa)
LOC102359041Zgc:153993. (208 aa)
MAPKAPK5MAPK activated protein kinase 5. (471 aa)
TLK1Tousled like kinase 1. (485 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (710 aa)
STK38LNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (459 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (658 aa)
STK32BSerine/threonine kinase 32B. (264 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1415 aa)
BRSK2Protein kinase domain-containing protein. (264 aa)
MGAT5BAlpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B. (649 aa)
LATS1Large tumor suppressor kinase 1. (1140 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (667 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2654 aa)
CDC7Cell division cycle 7. (560 aa)
H3AND1_LATCHUncharacterized protein. (239 aa)
RPS6KA6Ribosomal protein S6 kinase. (726 aa)
STK32CSerine/threonine kinase 32C. (384 aa)
POGLUT2Protein O-glucosyltransferase 2. (541 aa)
POGLUT3Protein O-glucosyltransferase 3. (509 aa)
H3B6K7_LATCHIKKbetaNEMObind domain-containing protein. (241 aa)
HIPK1Homeodomain interacting protein kinase 1. (1225 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1462 aa)
KIAA1549Si:ch211-1e14.1. (1462 aa)
LOC102365238Ribosomal protein S6 kinase. (740 aa)
H3B8L2_LATCHProtein kinase domain-containing protein. (82 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (423 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
CLSPNClaspin. (1326 aa)
PBKPDZ binding kinase. (336 aa)
LOC102366055Uncharacterized protein. (579 aa)
SPOCK2SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (362 aa)
H3BCX1_LATCHUncharacterized protein. (79 aa)
HIPK3Homeodomain interacting protein kinase 3. (1204 aa)
PINK1PTEN induced kinase 1. (467 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (386 aa)
NLKMitogen-activated protein kinase. (382 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (480 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (743 aa)
CSNK1A1Casein kinase 1 alpha 1. (287 aa)
H3AJ82_LATCHUncharacterized protein. (398 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (269 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3451 aa)
POGLUT1Protein O-glucosyltransferase 1. (351 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (573 aa)
SGK3Non-specific serine/threonine protein kinase. (495 aa)
TNKSPoly [ADP-ribose] polymerase. (1233 aa)
TTBK1Uncharacterized protein. (280 aa)
VRK2VRK serine/threonine kinase 2. (482 aa)
TLK2Tousled like kinase 2. (747 aa)
CSNK1ECasein kinase 1, epsilon; Belongs to the protein kinase superfamily. (418 aa)
PRKXProtein kinase X-linked; Belongs to the protein kinase superfamily. (285 aa)
BRSK1BR serine/threonine kinase 1. (782 aa)
H3AGH2_LATCHNeuron-derived neurotrophic factor, like. (567 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
RPS6KA1Non-specific serine/threonine protein kinase. (712 aa)
PKN2Protein kinase N2. (993 aa)
LOC102361574Non-specific serine/threonine protein kinase. (340 aa)
GALNT1Polypeptide N-acetylgalactosaminyltransferase. (557 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
HPF1Histone PARylation factor 1. (343 aa)
PDK3Protein-serine/threonine kinase. (407 aa)
GSK3AGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (463 aa)
LOC102353948Nemo-like kinase, type 1. (336 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (700 aa)
BAXUncharacterized protein. (223 aa)
H3ABK5_LATCHProtein kinase domain-containing protein. (360 aa)
MAPKAPK2MAPK activated protein kinase 2. (332 aa)
ILKIntegrin linked kinase. (417 aa)
LOC102350595Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (351 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1299 aa)
PRKAA2Non-specific serine/threonine protein kinase. (553 aa)
LOC102362603Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (551 aa)
LOC102361440Si:ch73-60h1.1. (384 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
SYKTyrosine-protein kinase. (616 aa)
RPS6KA5Ribosomal protein S6 kinase. (767 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (462 aa)
RPS6KB1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (443 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1491 aa)
LRRK2Leucine rich repeat kinase 2. (2508 aa)
CSNK1G2Casein kinase 1 gamma 2; Belongs to the protein kinase superfamily. (458 aa)
NDNFNeuron derived neurotrophic factor. (571 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
H3B0H2_LATCHUncharacterized protein. (441 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2113 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)
TBK1TANK binding kinase 1. (675 aa)
CSNK1DCasein kinase 1 delta. (417 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4083 aa)
H3B277_LATCHUncharacterized protein. (4290 aa)
UHMK1U2AF homology motif kinase 1. (435 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1350 aa)
GAS6Uncharacterized protein. (681 aa)
DCLK1Doublecortin like kinase 1; Belongs to the protein kinase superfamily. (434 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (479 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (589 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (684 aa)
H3B4R6_LATCHUncharacterized protein. (956 aa)
LOC102355470Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (279 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (456 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (390 aa)
PKN1Uncharacterized protein. (546 aa)
LATS2Large tumor suppressor kinase 2. (1108 aa)
H3AKB9_LATCHUncharacterized protein. (498 aa)
H3AKN9_LATCHC2 domain-containing protein. (130 aa)
MORC3MORC family CW-type zinc finger 3. (831 aa)
DYRK4Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4. (615 aa)
PRKCHProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (708 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1046 aa)
GALNT16Polypeptide N-acetylgalactosaminyltransferase 16; Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. (416 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (315 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (488 aa)
NTMT1N-terminal Xaa-Pro-Lys N-methyltransferase 1. (223 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (765 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
TTKTTK protein kinase. (889 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (958 aa)
LOC102356233TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (574 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
EPOErythropoietin. (179 aa)
HIPK4Homeodomain interacting protein kinase 4. (614 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (563 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1664 aa)
RPS6KA3Ribosomal protein S6 kinase A3. (709 aa)
PRKCEProtein kinase C, epsilon b. (347 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (805 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (1298 aa)
TSSK4Testis specific serine kinase 4; Belongs to the protein kinase superfamily. (368 aa)
ATMATM serine/threonine kinase. (2375 aa)
CAMK1Calcium/calmodulin dependent protein kinase I. (365 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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