STRINGSTRING
FUCA2 FUCA2 MAN2B2 MAN2B2 H2ZS97_LATCH H2ZS97_LATCH ADIPOQ ADIPOQ OMA1 OMA1 ADPGK ADPGK GPI GPI PGM2 PGM2 PGM1 PGM1 ATF3 ATF3 MPI MPI SORD SORD PDK4 PDK4 MAN2A1 MAN2A1 B3GLCT B3GLCT FOXK1 FOXK1 PRKAA1 PRKAA1 FOXK2 FOXK2 ATF4 ATF4 CRTC2 CRTC2 IGF2 IGF2 PMM2 PMM2 GAPDHS GAPDHS POFUT1 POFUT1 INPPL1 INPPL1 GALM GALM PDK2 PDK2 TPI1 TPI1 HK3 HK3 PGM2L1 PGM2L1 POFUT2 POFUT2 KAT2B KAT2B H3ACE0_LATCH H3ACE0_LATCH LTA LTA H3AEV1_LATCH H3AEV1_LATCH CDV3 CDV3 LEPR LEPR H3AGH0_LATCH H3AGH0_LATCH H3AHJ4_LATCH H3AHJ4_LATCH CRY1 CRY1 LOC102354904 LOC102354904 HKDC1 HKDC1 KCNQ1 KCNQ1 ALDOC ALDOC FBN1 FBN1 ALDOA ALDOA HK1 HK1 H3AM67_LATCH H3AM67_LATCH BRAT1 BRAT1 BAD BAD LEP LEP FBP1 FBP1 FUCA1 FUCA1 LOC102365364 LOC102365364 FBP2 FBP2 PDHA1 PDHA1 PPARA PPARA KBTBD2 KBTBD2 PMM1 PMM1 GAPDH GAPDH PFKFB1 PFKFB1 GALE GALE LOC102351332 LOC102351332 PDHB PDHB H3AWN2_LATCH H3AWN2_LATCH DCXR DCXR GCK GCK PGK1 PGK1 GALK2 GALK2 PFKP PFKP C1QTNF9 C1QTNF9 LOC102351582 LOC102351582 GALK1 GALK1 KHK KHK LOC102345467 LOC102345467 TP53 TP53 PPARGC1A PPARGC1A WDTC1 WDTC1 H3B2X1_LATCH H3B2X1_LATCH H6PD H6PD MAN2B1 MAN2B1 PIK3CA PIK3CA DLAT DLAT MAN2A2 MAN2A2 CHST15 CHST15 GDPGP1 GDPGP1 PDX1 PDX1 MAN2C1 MAN2C1 KCNJ11 KCNJ11 LOC102346019 LOC102346019 HK2 HK2 PFKFB3 PFKFB3 LOC102354033 LOC102354033 TKFC TKFC PCK1 PCK1 TIGAR TIGAR CHST1 CHST1 MDH2 MDH2 PC PC LRP5 LRP5 C1QTNF12 C1QTNF12 PFKFB2 PFKFB2 PFKM PFKM LOC102360349 LOC102360349 G6PC G6PC APOD APOD ALDOB ALDOB G6PD G6PD SLC37A4 SLC37A4 G6PC2 G6PC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FUCA2Alpha-L-fucosidase 2. (384 aa)
MAN2B2Alpha-mannosidase. (890 aa)
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (259 aa)
OMA1OMA1 zinc metallopeptidase. (358 aa)
ADPGKADP dependent glucokinase. (479 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (555 aa)
PGM2Phosphoglucomutase 2; Belongs to the phosphohexose mutase family. (537 aa)
PGM1Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (593 aa)
ATF3Activating transcription factor 3. (179 aa)
MPIMannose-6-phosphate isomerase. (422 aa)
SORDSorbitol dehydrogenase. (356 aa)
PDK4Protein-serine/threonine kinase. (370 aa)
MAN2A1Alpha-mannosidase. (826 aa)
B3GLCTBeta 3-glucosyltransferase. (502 aa)
FOXK1Forkhead box K1. (673 aa)
PRKAA1Non-specific serine/threonine protein kinase. (552 aa)
FOXK2Forkhead box K2. (499 aa)
ATF4Activating transcription factor 4. (374 aa)
CRTC2CREB regulated transcription coactivator 2. (691 aa)
IGF2Insulin like growth factor 2. (207 aa)
PMM2Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (249 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (396 aa)
POFUT1Protein O-fucosyltransferase 1. (329 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1220 aa)
GALMAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (352 aa)
PDK2Protein-serine/threonine kinase. (540 aa)
TPI1Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (262 aa)
HK3Hexokinase 3. (908 aa)
PGM2L1Phosphoglucomutase 2 like 1; Belongs to the phosphohexose mutase family. (528 aa)
POFUT2Protein O-fucosyltransferase 2. (441 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (793 aa)
H3ACE0_LATCHInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
LTALymphotoxin alpha. (166 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
CDV3CDV3 homolog. (258 aa)
LEPRLeptin receptor. (1149 aa)
H3AGH0_LATCHUncharacterized protein. (2690 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
CRY1Cryptochrome circadian regulator 1. (653 aa)
LOC102354904Uncharacterized protein. (648 aa)
HKDC1Hexokinase domain containing 1. (923 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (340 aa)
FBN1Fibrillin 1. (2872 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
HK1Hexokinase 1. (919 aa)
H3AM67_LATCHHECT domain-containing protein. (359 aa)
BRAT1BRCA1 associated ATM activator 1. (842 aa)
BADUncharacterized protein. (175 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
FUCA1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (464 aa)
LOC102365364Cryptochrome circadian regulator 3a. (616 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (302 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
KBTBD2Kelch repeat and BTB domain containing 2. (623 aa)
PMM1Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (259 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (478 aa)
GALEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (350 aa)
LOC102351332Zgc:158659; Belongs to the PI3/PI4-kinase family. (1067 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (393 aa)
H3AWN2_LATCHCryptochrome circadian regulator 4. (531 aa)
DCXRDicarbonyl and L-xylulose reductase. (244 aa)
GCKPhosphotransferase. (400 aa)
PGK1Phosphoglycerate kinase. (389 aa)
GALK2Galactokinase 2. (459 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (784 aa)
C1QTNF9C1q domain-containing protein. (198 aa)
LOC102351582SH2 domain-containing protein. (892 aa)
GALK1Galactokinase 1. (394 aa)
KHKKetohexokinase. (343 aa)
LOC1023454676-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a. (474 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
PPARGC1APPARG coactivator 1 alpha. (783 aa)
WDTC1WD and tetratricopeptide repeats 1. (646 aa)
H3B2X1_LATCHUncharacterized protein. (738 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (793 aa)
MAN2B1Alpha-mannosidase. (973 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (629 aa)
MAN2A2Alpha-mannosidase. (1152 aa)
CHST15Carbohydrate sulfotransferase 15. (517 aa)
GDPGP1Uncharacterized protein. (382 aa)
PDX1Pancreatic and duodenal homeobox 1. (257 aa)
MAN2C1Mannosidase alpha class 2C member 1. (1003 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (392 aa)
LOC102346019C1q domain-containing protein. (226 aa)
HK2Hexokinase 2. (918 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (509 aa)
LOC102354033ADP-dependent glucokinase 2. (441 aa)
TKFCTriokinase and FMN cyclase. (582 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (212 aa)
CHST1Sulfotransferase; Belongs to the sulfotransferase 1 family. (419 aa)
MDH2Malate dehydrogenase. (337 aa)
PCPyruvate carboxylase. (722 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
C1QTNF12C1q and TNF related 12. (265 aa)
PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (494 aa)
PFKMPhosphofructokinase, muscle. (830 aa)
LOC102360349Glyco_hydro_38N domain-containing protein. (357 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
APODApolipoprotein D; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
SLC37A4Solute carrier family 37 member 4. (441 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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