STRINGSTRING
FLT4 FLT4 H2ZS19_LATCH H2ZS19_LATCH LOC102349509 LOC102349509 MFHAS1 MFHAS1 LOC102355203 LOC102355203 FBXO41 FBXO41 SMG7 SMG7 H2ZVF8_LATCH H2ZVF8_LATCH MASTL MASTL PPP6R1 PPP6R1 H2ZX51_LATCH H2ZX51_LATCH ITGA1 ITGA1 MTMR3 MTMR3 PPP1R3B PPP1R3B STRN4 STRN4 H2ZZW6_LATCH H2ZZW6_LATCH AKAP11 AKAP11 SMTNL1 SMTNL1 PPP1R9A PPP1R9A TCTEX1D4 TCTEX1D4 H3A214_LATCH H3A214_LATCH PPME1 PPME1 LRRD1 LRRD1 H3A2Y4_LATCH H3A2Y4_LATCH PPP1R10 PPP1R10 PPP1R3E PPP1R3E ARPP19 ARPP19 H3A807_LATCH H3A807_LATCH HSP90B1 HSP90B1 LOC102365394 LOC102365394 KIFAP3 KIFAP3 JUP JUP GNA12 GNA12 STX17 STX17 PPP1R3C PPP1R3C H3ACR7_LATCH H3ACR7_LATCH MVP MVP PDLIM4 PDLIM4 H3AEX8_LATCH H3AEX8_LATCH H3AHJ4_LATCH H3AHJ4_LATCH H3AJC3_LATCH H3AJC3_LATCH KCNQ1 KCNQ1 TRAF3 TRAF3 GTF2F1 GTF2F1 STRN3 STRN3 MTMR4 MTMR4 PPP6R2 PPP6R2 BAD BAD ADCY8 ADCY8 ROS1 ROS1 SMG5 SMG5 C20orf27 C20orf27 MTMR9 MTMR9 LOC102365688 LOC102365688 NEK2 NEK2 CDH5 CDH5 LOC102354453 LOC102354453 GRIN3A GRIN3A ATP2B4 ATP2B4 STAT3 STAT3 FBXL2 FBXL2 PHACTR1 PHACTR1 IGBP1 IGBP1 H3AZ94_LATCH H3AZ94_LATCH PTPA PTPA MAP2K7 MAP2K7 MET MET SHOC2 SHOC2 TP53 TP53 CSF1R CSF1R PPP1R3G PPP1R3G PPP1R16B PPP1R16B CADM4 CADM4 RACK1 RACK1 CTNNB1 CTNNB1 CDC27 CDC27 BOD1 BOD1 SKAP2 SKAP2 ANAPC7 ANAPC7 AP3B1 AP3B1 STRN STRN AP3B2 AP3B2 PHACTR3 PHACTR3 PPP1R3D PPP1R3D PHACTR4 PHACTR4 ANKLE2 ANKLE2 CTTNBP2NL CTTNBP2NL ANAPC5 ANAPC5 STYXL1 STYXL1 PPP6R3 PPP6R3 AMBRA1 AMBRA1 SMTNL2 SMTNL2 LOC102351798 LOC102351798 LGALS3 LGALS3 EIF2AK3 EIF2AK3 LOC106706658 LOC106706658 PPP1R9B PPP1R9B ENSA ENSA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1394 aa)
H2ZS19_LATCHUncharacterized protein. (68 aa)
LOC102349509Ig-like domain-containing protein. (269 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (635 aa)
LOC102355203Na_H_Exchanger domain-containing protein. (161 aa)
FBXO41F-box protein 41. (765 aa)
SMG7SMG7 nonsense mediated mRNA decay factor. (1197 aa)
H2ZVF8_LATCHUncharacterized protein. (313 aa)
MASTLMicrotubule associated serine/threonine kinase like. (880 aa)
PPP6R1Protein phosphatase 6 regulatory subunit 1. (724 aa)
H2ZX51_LATCHUncharacterized protein. (327 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1185 aa)
MTMR3Myotubularin related protein 3. (1222 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (305 aa)
STRN4Striatin 4. (715 aa)
H2ZZW6_LATCHProtein kinase domain-containing protein. (513 aa)
AKAP11A-kinase anchoring protein 11. (1808 aa)
SMTNL1Calponin-homology (CH) domain-containing protein. (388 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1320 aa)
TCTEX1D4Tctex1 domain containing 4. (133 aa)
H3A214_LATCHUncharacterized protein. (559 aa)
PPME1Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. (294 aa)
LRRD1Leucine rich repeats and death domain containing 1. (717 aa)
H3A2Y4_LATCHProtein phosphatase 1 regulatory subunit. (319 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (792 aa)
PPP1R3EProtein phosphatase 1 regulatory subunit 3E. (294 aa)
ARPP19cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (117 aa)
H3A807_LATCHUncharacterized protein. (507 aa)
HSP90B1Heat shock protein 90 beta family member 1. (800 aa)
LOC102365394F-box domain-containing protein. (435 aa)
KIFAP3Kinesin associated protein 3. (795 aa)
JUPJunction plakoglobin. (694 aa)
GNA12G protein subunit alpha 12. (382 aa)
STX17Syntaxin 17. (308 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (319 aa)
H3ACR7_LATCHUncharacterized protein. (460 aa)
MVPMajor vault protein. (856 aa)
PDLIM4PDZ and LIM domain 4. (233 aa)
H3AEX8_LATCHCBM21 domain-containing protein. (304 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
H3AJC3_LATCHGalectin. (249 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (525 aa)
STRN3Striatin 3. (788 aa)
MTMR4Myotubularin related protein 4. (1171 aa)
PPP6R2Protein phosphatase 6 regulatory subunit 2. (865 aa)
BADUncharacterized protein. (175 aa)
ADCY8AC_N domain-containing protein. (266 aa)
ROS1Tyrosine-protein kinase receptor. (2138 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (1046 aa)
C20orf27Chromosome 20 open reading frame 27. (106 aa)
MTMR9Myotubularin related protein 9. (554 aa)
LOC102365688Protein phosphatase 1 regulatory subunit 9A-like B. (908 aa)
NEK2NIMA related kinase 2. (445 aa)
CDH5Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
LOC102354453Uncharacterized protein. (230 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1109 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1233 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
FBXL2F-box and leucine rich repeat protein 2. (432 aa)
PHACTR1Phosphatase and actin regulator. (396 aa)
IGBP1Immunoglobulin (CD79A) binding protein 1. (353 aa)
H3AZ94_LATCHTNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (360 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (439 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1385 aa)
SHOC2SHOC2 leucine rich repeat scaffold protein. (584 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
CSF1RColony stimulating factor 1 receptor. (968 aa)
PPP1R3GCBM21 domain-containing protein. (231 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (578 aa)
CADM4Cell adhesion molecule 4. (380 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
CTNNB1Catenin beta 1. (781 aa)
CDC27Cell division cycle 27. (833 aa)
BOD1Uncharacterized protein. (177 aa)
SKAP2Src kinase associated phosphoprotein 2. (276 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1105 aa)
STRNStriatin. (789 aa)
AP3B2AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1077 aa)
PHACTR3Phosphatase and actin regulator. (454 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit 3D. (307 aa)
PHACTR4Phosphatase and actin regulator. (702 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (956 aa)
CTTNBP2NLCTTNBP2 N-terminal like. (644 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
STYXL1Serine/threonine/tyrosine interacting-like 1. (324 aa)
PPP6R3Protein phosphatase 6 regulatory subunit 3. (912 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1195 aa)
SMTNL2Smoothelin, like. (470 aa)
LOC102351798Galectin. (167 aa)
LGALS3Galectin. (274 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (958 aa)
LOC106706658DUF3699 domain-containing protein. (338 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (857 aa)
ENSAEndosulfine alpha; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (118 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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