(12 nodes) Signal transduction involved in regulation of gene expression network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CER1	CTCK domain-containing protein. (257 aa)
	H3BFZ2_LATCH	BHLH domain-containing protein. (165 aa)
	H3BFW7_LATCH	BHLH domain-containing protein. (161 aa)
	DAND5	CTCK domain-containing protein. (247 aa)
	PAX6	Paired box 6. (463 aa)
	TRAF5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
	FGF5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	TRAF3IP2	SEFIR domain-containing protein. (379 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	GSC	Goosecoid homeobox. (243 aa)
	MSX1	Msh homeobox 1. (256 aa)
	LOC102358239	TRAF3 interacting protein 2-like. (392 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGF5	FGF8	ENSLACP00000016656	ENSLACP00000007843	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.669
FGF5	PAX6	ENSLACP00000016656	ENSLACP00000017411	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Paired box 6.	0.567
FGF8	FGF5	ENSLACP00000007843	ENSLACP00000016656	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.669
FGF8	MSX1	ENSLACP00000007843	ENSLACP00000004473	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Msh homeobox 1.	0.606
FGF8	PAX6	ENSLACP00000007843	ENSLACP00000017411	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Paired box 6.	0.691
LOC102358239	TRAF5	ENSLACP00000004237	ENSLACP00000017309	TRAF3 interacting protein 2-like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.505
MSX1	FGF8	ENSLACP00000004473	ENSLACP00000007843	Msh homeobox 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.606
PAX6	FGF5	ENSLACP00000017411	ENSLACP00000016656	Paired box 6.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.567
PAX6	FGF8	ENSLACP00000017411	ENSLACP00000007843	Paired box 6.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.691
TRAF3IP2	TRAF5	ENSLACP00000013509	ENSLACP00000017309	SEFIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.505
TRAF5	LOC102358239	ENSLACP00000017309	ENSLACP00000004237	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TRAF3 interacting protein 2-like.	0.505
TRAF5	TRAF3IP2	ENSLACP00000017309	ENSLACP00000013509	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	SEFIR domain-containing protein.	0.505