(15 nodes) Desmosome network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3A0S9_LATCH	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (898 aa)
	LOC102361492	Uncharacterized protein. (1086 aa)
	KLHL35	Kelch like family member 35. (600 aa)
	VCL	Vinculin. (832 aa)
	PNN	Pinin, desmosome associated protein. (677 aa)
	JUP	Junction plakoglobin. (694 aa)
	PKP2	Uncharacterized protein. (815 aa)
	KLHL6	Kelch like family member 6. (613 aa)
	KLHL24	Kelch like family member 24. (596 aa)
	H3AXL4_LATCH	Uncharacterized protein. (953 aa)
	JAM3	Junctional adhesion molecule 3. (208 aa)
	PKP1	Plakophilin 1. (744 aa)
	KAZN	Uncharacterized protein. (640 aa)
	LOC102361769	Uncharacterized protein. (924 aa)
	KAZN-2	Uncharacterized protein. (125 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3A0S9_LATCH	H3AXL4_LATCH	ENSLACP00000003250	ENSLACP00000014385	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Uncharacterized protein.	0.721
H3A0S9_LATCH	JUP	ENSLACP00000003250	ENSLACP00000006244	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Junction plakoglobin.	0.913
H3A0S9_LATCH	LOC102361492	ENSLACP00000003250	ENSLACP00000002704	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Uncharacterized protein.	0.721
H3A0S9_LATCH	LOC102361769	ENSLACP00000003250	ENSLACP00000005404	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Uncharacterized protein.	0.737
H3A0S9_LATCH	PKP1	ENSLACP00000003250	ENSLACP00000013195	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Plakophilin 1.	0.776
H3A0S9_LATCH	PKP2	ENSLACP00000003250	ENSLACP00000023417	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Uncharacterized protein.	0.888
H3AXL4_LATCH	H3A0S9_LATCH	ENSLACP00000014385	ENSLACP00000003250	Uncharacterized protein.	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.721
H3AXL4_LATCH	JUP	ENSLACP00000014385	ENSLACP00000006244	Uncharacterized protein.	Junction plakoglobin.	0.735
H3AXL4_LATCH	PKP1	ENSLACP00000014385	ENSLACP00000013195	Uncharacterized protein.	Plakophilin 1.	0.671
H3AXL4_LATCH	PKP2	ENSLACP00000014385	ENSLACP00000023417	Uncharacterized protein.	Uncharacterized protein.	0.693
JUP	H3A0S9_LATCH	ENSLACP00000006244	ENSLACP00000003250	Junction plakoglobin.	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.913
JUP	H3AXL4_LATCH	ENSLACP00000006244	ENSLACP00000014385	Junction plakoglobin.	Uncharacterized protein.	0.735
JUP	LOC102361492	ENSLACP00000006244	ENSLACP00000002704	Junction plakoglobin.	Uncharacterized protein.	0.735
JUP	LOC102361769	ENSLACP00000006244	ENSLACP00000005404	Junction plakoglobin.	Uncharacterized protein.	0.735
JUP	PKP1	ENSLACP00000006244	ENSLACP00000013195	Junction plakoglobin.	Plakophilin 1.	0.840
JUP	PKP2	ENSLACP00000006244	ENSLACP00000023417	Junction plakoglobin.	Uncharacterized protein.	0.891
JUP	VCL	ENSLACP00000006244	ENSLACP00000000289	Junction plakoglobin.	Vinculin.	0.774
LOC102361492	H3A0S9_LATCH	ENSLACP00000002704	ENSLACP00000003250	Uncharacterized protein.	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.721
LOC102361492	JUP	ENSLACP00000002704	ENSLACP00000006244	Uncharacterized protein.	Junction plakoglobin.	0.735
LOC102361492	PKP1	ENSLACP00000002704	ENSLACP00000013195	Uncharacterized protein.	Plakophilin 1.	0.774