STRINGSTRING
RELCH RELCH VPS4B VPS4B STARD4 STARD4 CFTR CFTR ABCG1 ABCG1 STARD3NL STARD3NL APOM APOM PODN PODN SERAC1 SERAC1 OSBPL2 OSBPL2 LIMA1 LIMA1 VPS4A VPS4A STAR STAR H3AMG4_LATCH H3AMG4_LATCH SYT7 SYT7 LIPC LIPC LDLRAP1 LDLRAP1 SPG11 SPG11 PODNL1 PODNL1 STARD5 STARD5 LOC102365332 LOC102365332 APOA4 APOA4 ABCG8 ABCG8 CEL CEL H3B6R7_LATCH H3B6R7_LATCH ABCG5 ABCG5 STARD3 STARD3 ARV1 ARV1 ABCG4 ABCG4 LRP6 LRP6 NPC2 NPC2 NPC1L1 NPC1L1 NPC1 NPC1 LCAT LCAT APOB APOB SCARB1 SCARB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1037 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (448 aa)
STARD4StAR related lipid transfer domain containing 4. (216 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
ABCG1ATP binding cassette subfamily G member 1. (649 aa)
STARD3NLSTARD3 N-terminal like. (234 aa)
APOMApolipoprotein M. (194 aa)
PODNPodocan. (621 aa)
SERAC1Serine active site containing 1. (657 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (475 aa)
LIMA1LIM domain and actin binding 1. (545 aa)
VPS4AVacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (437 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
H3AMG4_LATCHUncharacterized protein. (141 aa)
SYT7Synaptotagmin 7. (286 aa)
LIPCLipase C, hepatic type. (503 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1b. (316 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2438 aa)
PODNL1Podocan like 1. (599 aa)
STARD5StAR related lipid transfer domain containing 5. (213 aa)
LOC102365332Apolipoprotein Ea. (278 aa)
APOA4Apolipoprotein A4. (367 aa)
ABCG8ATP binding cassette subfamily G member 8. (677 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (552 aa)
H3B6R7_LATCHIon_trans domain-containing protein. (303 aa)
ABCG5ATP binding cassette subfamily G member 5. (438 aa)
STARD3StAR related lipid transfer domain containing 3. (445 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (232 aa)
ABCG4ATP binding cassette subfamily G member 4. (653 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
NPC2NPC intracellular cholesterol transporter 2. (148 aa)
NPC1L1NPC1 like intracellular cholesterol transporter 1. (1104 aa)
NPC1NPC intracellular cholesterol transporter 1. (1284 aa)
LCATLecithin-cholesterol acyltransferase. (428 aa)
APOBApolipoprotein B. (4644 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (521 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.