STRINGSTRING
CENPV CENPV LOC102356000 LOC102356000 H2ZS49_LATCH H2ZS49_LATCH VPS4B VPS4B DCTN3 DCTN3 MPLKIP MPLKIP RAB11FIP4 RAB11FIP4 GNL3 GNL3 ARL3 ARL3 TEX14 TEX14 H2ZX25_LATCH H2ZX25_LATCH CTDP1 CTDP1 URB2 URB2 ERH ERH IST1 IST1 LZTS2 LZTS2 LOC102357019 LOC102357019 UVRAG UVRAG PITPNM1 PITPNM1 CRMP1 CRMP1 PTCH1 PTCH1 EXOC4 EXOC4 LOC102349711 LOC102349711 C9orf72 C9orf72 POLDIP2 POLDIP2 MDP1 MDP1 PLK1 PLK1 LOC102365031 LOC102365031 MAP11 MAP11 NAT10 NAT10 CHMP4A CHMP4A ARF6 ARF6 H3A6M6_LATCH H3A6M6_LATCH LYRM1 LYRM1 CHMP5 CHMP5 HSP90B1 HSP90B1 CHMP4B CHMP4B SPART SPART RALA RALA DDX11 DDX11 RNF8 RNF8 LOC102358108 LOC102358108 TTC23L TTC23L GNAI1 GNAI1 PKN2 PKN2 LOC102356960 LOC102356960 ALKBH4 ALKBH4 TBCK TBCK CHMP4C CHMP4C LOC102345131 LOC102345131 JTB JTB SHCBP1 SHCBP1 KLHDC8A KLHDC8A VPS4A VPS4A H3AKM3_LATCH H3AKM3_LATCH KIF14 KIF14 KLHDC8B KLHDC8B SH3GLB1 SH3GLB1 LOC102353741 LOC102353741 TSG101 TSG101 USP3 USP3 PDCD6IP PDCD6IP H3AS24_LATCH H3AS24_LATCH H3ASN6_LATCH H3ASN6_LATCH NEK2 NEK2 H3ASX0_LATCH H3ASX0_LATCH DCDC1 DCDC1 LOC102361424 LOC102361424 DTNBP1 DTNBP1 LOC102346472 LOC102346472 NUDC NUDC TTC28 TTC28 KIF23 KIF23 H3AWR1_LATCH H3AWR1_LATCH TXNDC9 TXNDC9 ECT2 ECT2 ANKRD45 ANKRD45 GNAO1 GNAO1 MITD1 MITD1 WIZ WIZ CEP44 CEP44 CCDC124 CCDC124 SSNA1 SSNA1 IL16 IL16 CLIC4 CLIC4 CENPC CENPC RACK1 RACK1 SEPTIN2 SEPTIN2 PKN1 PKN1 RALB RALB CHMP6 CHMP6 BIRC6 BIRC6 CDC42 CDC42 EXOC2 EXOC2 H3B866_LATCH H3B866_LATCH PRC1 PRC1 ZFYVE19 ZFYVE19 PIK3C3 PIK3C3 RCC2 RCC2 LOC102345089 LOC102345089 SVIL SVIL CEP55 CEP55 EXOC7 EXOC7 USP50 USP50 AGBL5 AGBL5 CENPF CENPF KIF20A KIF20A PSRC1 PSRC1 DCDC1-2 DCDC1-2 LOC102360017 LOC102360017 CDK1 CDK1 EXOC5 EXOC5 LOC102349333 LOC102349333 CIT CIT ANXA11 ANXA11 USP8 USP8 HSPA5 HSPA5 RACGAP1 RACGAP1 MICAL3 MICAL3 ENTR1 ENTR1 GNAI3 GNAI3 ZFYVE26 ZFYVE26 BIRC5 BIRC5 RAB11FIP3 RAB11FIP3 KATNBL1 KATNBL1 INCENP INCENP CCDC69 CCDC69 MAP10 MAP10 SCCPDH SCCPDH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CENPVCentromere protein V. (159 aa)
LOC102356000Uncharacterized protein. (211 aa)
H2ZS49_LATCHEnhancer of rudimentary homolog; May have a role in the cell cycle. (118 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (448 aa)
DCTN3Dynactin subunit 3. (187 aa)
MPLKIPM-phase specific PLK1 interacting protein. (162 aa)
RAB11FIP4RAB11 family interacting protein 4. (530 aa)
GNL3G protein nucleolar 3. (564 aa)
ARL3ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (203 aa)
TEX14Protein kinase domain-containing protein. (937 aa)
H2ZX25_LATCHANK_REP_REGION domain-containing protein. (269 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (846 aa)
URB2URB2 ribosome biogenesis homolog. (1538 aa)
ERHEnhancer of rudimentary homolog; May have a role in the cell cycle. (110 aa)
IST1IST1 factor associated with ESCRT-III. (260 aa)
LZTS2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (678 aa)
LOC102357019Uncharacterized protein. (143 aa)
UVRAGUV radiation resistance associated. (407 aa)
PITPNM1Phosphatidylinositol transfer protein membrane associated 1. (1298 aa)
CRMP1Collapsin response mediator protein 1. (659 aa)
PTCH1Patched 1. (1287 aa)
EXOC4Exocyst complex component 4. (480 aa)
LOC102349711Uncharacterized protein. (935 aa)
C9orf72C9orf72-SMCR8 complex subunit. (482 aa)
POLDIP2DNA polymerase delta interacting protein 2. (369 aa)
MDP1Si:dkeyp-27c8.2. (164 aa)
PLK1Serine/threonine-protein kinase PLK. (595 aa)
LOC102365031ApaG domain-containing protein. (345 aa)
MAP11Microtubule associated protein 11. (415 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1025 aa)
CHMP4ACharged multivesicular body protein 4A. (221 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
H3A6M6_LATCHKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (785 aa)
LYRM1LYR motif containing 1; Belongs to the complex I LYR family. (121 aa)
CHMP5Charged multivesicular body protein 5. (220 aa)
HSP90B1Heat shock protein 90 beta family member 1. (800 aa)
CHMP4BCharged multivesicular body protein 4B. (225 aa)
SPARTSpartin. (664 aa)
RALARAS like proto-oncogene A. (206 aa)
DDX11DEAD/H-box helicase 11. (909 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (542 aa)
LOC102358108Guanine nucleotide binding protein (G protein) alpha v1. (362 aa)
TTC23LTetratricopeptide repeat domain 23 like. (346 aa)
GNAI1G protein subunit alpha i1. (326 aa)
PKN2Protein kinase N2. (993 aa)
LOC102356960Charged multivesicular body protein 3. (220 aa)
ALKBH4AlkB homolog 4, lysine demethylase. (328 aa)
TBCKTBC1 domain containing kinase. (892 aa)
CHMP4CUncharacterized protein. (240 aa)
LOC102345131Si:ch1073-416j23.1. (581 aa)
JTBUncharacterized protein. (163 aa)
SHCBP1SHC binding and spindle associated 1. (640 aa)
KLHDC8AKelch domain containing 8A. (350 aa)
VPS4AVacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (437 aa)
H3AKM3_LATCHUncharacterized protein. (856 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1644 aa)
KLHDC8BKelch domain containing 8B. (359 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (384 aa)
LOC102353741Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (266 aa)
TSG101Tumor susceptibility 101. (392 aa)
USP3Ubiquitin carboxyl-terminal hydrolase. (522 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (732 aa)
H3AS24_LATCHUncharacterized protein. (270 aa)
H3ASN6_LATCHHP domain-containing protein. (111 aa)
NEK2NIMA related kinase 2. (445 aa)
H3ASX0_LATCHKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (397 aa)
DCDC1Doublecortin domain containing 1. (819 aa)
LOC102361424Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
DTNBP1Dystrobrevin binding protein 1. (355 aa)
LOC102346472Uncharacterized protein. (168 aa)
NUDCNuclear distribution C, dynein complex regulator. (337 aa)
TTC28TPR_REGION domain-containing protein. (2002 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (961 aa)
H3AWR1_LATCHUncharacterized protein. (471 aa)
TXNDC9Thioredoxin domain containing 9. (225 aa)
ECT2Epithelial cell transforming 2. (919 aa)
ANKRD45ANK_REP_REGION domain-containing protein. (233 aa)
GNAO1G protein subunit alpha o1. (258 aa)
MITD1Microtubule interacting and trafficking domain containing 1. (180 aa)
WIZWIZ zinc finger. (1428 aa)
CEP44Centrosomal protein 44. (393 aa)
CCDC124Coiled-coil domain containing 124. (223 aa)
SSNA1Sjogren syndrome nuclear autoantigen 1. (115 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1208 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa)
CENPCCENP-C_C domain-containing protein. (824 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
SEPTIN2Zgc:63587; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (350 aa)
PKN1Uncharacterized protein. (546 aa)
RALBRAS like proto-oncogene B. (225 aa)
CHMP6Charged multivesicular body protein 6. (146 aa)
BIRC6Baculoviral IAP repeat containing 6. (4819 aa)
CDC42Cell division cycle 42. (156 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (794 aa)
H3B866_LATCHTPR_REGION domain-containing protein. (110 aa)
PRC1Protein regulator of cytokinesis 1. (616 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (446 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (825 aa)
RCC2Regulator of chromosome condensation 2. (498 aa)
LOC102345089Uncharacterized protein. (1259 aa)
SVILSupervillin. (2196 aa)
CEP55Centrosomal protein 55. (468 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (715 aa)
USP50Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (358 aa)
AGBL5ATP/GTP binding protein like 5. (986 aa)
CENPFCentromere protein F. (3070 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (905 aa)
PSRC1GTSE1_N domain-containing protein. (399 aa)
DCDC1-2Doublecortin domain-containing protein. (337 aa)
LOC102360017Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (895 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
EXOC5Exocyst complex component 5. (708 aa)
LOC102349333Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (176 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2066 aa)
ANXA11Annexin. (507 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1102 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
RACGAP1Rac GTPase activating protein 1. (635 aa)
MICAL3Microtubule associated monooxygenase, calponin and LIM domain containing 3. (1971 aa)
ENTR1Endosome associated trafficking regulator 1. (355 aa)
GNAI3Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
ZFYVE26Zinc finger FYVE-type containing 26. (2567 aa)
BIRC5Baculoviral IAP repeat containing 5. (139 aa)
RAB11FIP3RAB11 family interacting protein 3. (497 aa)
KATNBL1Katanin regulatory subunit B1 like 1. (319 aa)
INCENPINCENP_ARK-bind domain-containing protein. (887 aa)
CCDC69Coiled-coil domain containing 69. (267 aa)
MAP10HPHLAWLY domain-containing protein. (862 aa)
SCCPDHSaccharopine dehydrogenase (putative). (430 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.