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HTRA3 HTRA3 DLX1 DLX1 LOC102350164 LOC102350164 CER1 CER1 MSX1 MSX1 ITGA3 ITGA3 TNFAIP6 TNFAIP6 LOC102358266 LOC102358266 SPART SPART SMAD6 SMAD6 SMAD7 SMAD7 ILK ILK GREM1 GREM1 FKBP8 FKBP8 SFRP2 SFRP2 BAMBI BAMBI LOC102350487 LOC102350487 RNF165 RNF165 NOG NOG SMAD4 SMAD4 TWSG1 TWSG1 SFRP1 SFRP1 SKOR2 SKOR2 CHRD CHRD FBN1 FBN1 FSTL3 FSTL3 KDR KDR SFRP1-2 SFRP1-2 LEMD3 LEMD3 CHRDL1 CHRDL1 NBL1 NBL1 SOST SOST TBX20 TBX20 SORL1 SORL1 SOSTDC1 SOSTDC1 CTDSPL2 CTDSPL2 CDH5 CDH5 NUMA1 NUMA1 LOC102357384 LOC102357384 KIAA1324L KIAA1324L H3AVW8_LATCH H3AVW8_LATCH HJV HJV FST FST ZNF423 ZNF423 GREM2 GREM2 SKI SKI SFRP5 SFRP5 SKOR1 SKOR1 SMURF2 SMURF2 SKIL SKIL BMPR2 BMPR2 DAND5 DAND5 VWC2L VWC2L SULF1 SULF1 LOC102356742 LOC102356742 LEMD2 LEMD2 LOC102355199 LOC102355199 FBXL15 FBXL15 CCN1 CCN1 HOXA13 HOXA13 CRIM1 CRIM1 H3BEX6_LATCH H3BEX6_LATCH PPM1A PPM1A WNT1 WNT1 ACVRL1 ACVRL1 RBPMS2 RBPMS2 LOC102358988 LOC102358988 BMPER BMPER UBE2O UBE2O ENG ENG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HTRA3HtrA serine peptidase 3. (460 aa)
DLX1Distal-less homeobox 1. (253 aa)
LOC102350164Uncharacterized protein. (364 aa)
CER1CTCK domain-containing protein. (257 aa)
MSX1Msh homeobox 1. (256 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1012 aa)
TNFAIP6TNF alpha induced protein 6. (279 aa)
LOC102358266Dickkopf WNT signaling pathway inhibitor 1b. (261 aa)
SPARTSpartin. (664 aa)
SMAD6Mothers against decapentaplegic homolog. (485 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
ILKIntegrin linked kinase. (417 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (189 aa)
FKBP8Peptidylprolyl isomerase. (443 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
LOC102350487RGM domain family, member D. (443 aa)
RNF165Ring finger protein 165. (351 aa)
NOGNoggin; Belongs to the noggin family. (223 aa)
SMAD4MH2 domain-containing protein. (412 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (220 aa)
SFRP1NTR domain-containing protein. (128 aa)
SKOR2SKI family transcriptional corepressor 2. (721 aa)
CHRDChordin; Belongs to the chordin family. (948 aa)
FBN1Fibrillin 1. (2872 aa)
FSTL3Follistatin like 3. (248 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
SFRP1-2FZ domain-containing protein. (203 aa)
LEMD3LEM domain containing 3. (705 aa)
CHRDL1Chordin like 1. (458 aa)
NBL1NBL1, DAN family BMP antagonist. (184 aa)
SOSTSclerostin. (210 aa)
TBX20T-box transcription factor 20. (441 aa)
SORL1Sortilin-related receptor, L(DLR class) A repeats containing. (1410 aa)
SOSTDC1Sclerostin domain containing 1. (213 aa)
CTDSPL2FCP1 homology domain-containing protein. (2335 aa)
CDH5Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2155 aa)
LOC102357384Noggin; Belongs to the noggin family. (216 aa)
KIAA1324LKIAA1324 like. (965 aa)
H3AVW8_LATCHMothers against decapentaplegic homolog. (369 aa)
HJVHemojuvelin BMP co-receptor. (404 aa)
FSTFollistatin. (319 aa)
ZNF423Zinc finger protein 423. (1277 aa)
GREM2Gremlin 2, DAN family BMP antagonist. (167 aa)
SKISKI proto-oncogene. (702 aa)
SFRP5Secreted frizzled related protein 5. (309 aa)
SKOR1SKI family transcriptional corepressor 1. (787 aa)
SMURF2E3 ubiquitin-protein ligase. (754 aa)
SKILSKI like proto-oncogene. (691 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
DAND5CTCK domain-containing protein. (247 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (176 aa)
SULF1Sulfatase 1. (1129 aa)
LOC102356742Sizzled. (295 aa)
LEMD2LEM domain containing 2. (416 aa)
LOC102355199Uncharacterized protein. (301 aa)
FBXL15F-box and leucine rich repeat protein 15. (302 aa)
CCN1Cellular communication network factor 1. (368 aa)
HOXA13Homeobox A13b. (295 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (881 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (383 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (497 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (227 aa)
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
BMPERBMP binding endothelial regulator. (682 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1313 aa)
ENGEndoglin. (674 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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