(13 nodes) Mismatched DNA binding network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PMS1	PMS1 homolog 1, mismatch repair system component. (1040 aa)
	MSH6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa)
	MLH3	MutL homolog 3. (1437 aa)
	LOC102360187	MutS homolog 2 (E. coli). (447 aa)
	TDG	Thymine DNA glycosylase. (231 aa)
	PMS2	PMS1 homolog 2, mismatch repair system component. (872 aa)
	MUTYH	Uncharacterized protein. (140 aa)
	MSH4	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (955 aa)
	H2ZX83_LATCH	MutS homolog 2 (E. coli). (360 aa)
	APTX	Aprataxin. (372 aa)
	MSH3	MutS homolog 3; Component of the post-replicative DNA mismatch repair system (MMR). (798 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	MLH1	MutL homolog 1. (821 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APTX	MSH3	ENSLACP00000003789	ENSLACP00000003956	Aprataxin.	MutS homolog 3; Component of the post-replicative DNA mismatch repair system (MMR).	0.442
H2ZX83_LATCH	LOC102360187	ENSLACP00000002004	ENSLACP00000000628	MutS homolog 2 (E. coli).	MutS homolog 2 (E. coli).	0.989
H2ZX83_LATCH	MLH1	ENSLACP00000002004	ENSLACP00000008921	MutS homolog 2 (E. coli).	MutL homolog 1.	0.993
H2ZX83_LATCH	MLH3	ENSLACP00000002004	ENSLACP00000020860	MutS homolog 2 (E. coli).	MutL homolog 3.	0.931
H2ZX83_LATCH	MSH3	ENSLACP00000002004	ENSLACP00000003956	MutS homolog 2 (E. coli).	MutS homolog 3; Component of the post-replicative DNA mismatch repair system (MMR).	0.974
H2ZX83_LATCH	MSH4	ENSLACP00000002004	ENSLACP00000023534	MutS homolog 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.572
H2ZX83_LATCH	MSH6	ENSLACP00000002004	ENSLACP00000017187	MutS homolog 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.988
H2ZX83_LATCH	MUTYH	ENSLACP00000002004	ENSLACP00000023303	MutS homolog 2 (E. coli).	Uncharacterized protein.	0.543
H2ZX83_LATCH	PCNA	ENSLACP00000002004	ENSLACP00000006575	MutS homolog 2 (E. coli).	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.963
H2ZX83_LATCH	PMS1	ENSLACP00000002004	ENSLACP00000016464	MutS homolog 2 (E. coli).	PMS1 homolog 1, mismatch repair system component.	0.958
H2ZX83_LATCH	PMS2	ENSLACP00000002004	ENSLACP00000022793	MutS homolog 2 (E. coli).	PMS1 homolog 2, mismatch repair system component.	0.984
LOC102360187	H2ZX83_LATCH	ENSLACP00000000628	ENSLACP00000002004	MutS homolog 2 (E. coli).	MutS homolog 2 (E. coli).	0.989
LOC102360187	MLH1	ENSLACP00000000628	ENSLACP00000008921	MutS homolog 2 (E. coli).	MutL homolog 1.	0.995
LOC102360187	MLH3	ENSLACP00000000628	ENSLACP00000020860	MutS homolog 2 (E. coli).	MutL homolog 3.	0.944
LOC102360187	MSH3	ENSLACP00000000628	ENSLACP00000003956	MutS homolog 2 (E. coli).	MutS homolog 3; Component of the post-replicative DNA mismatch repair system (MMR).	0.979
LOC102360187	MSH4	ENSLACP00000000628	ENSLACP00000023534	MutS homolog 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.623
LOC102360187	MSH6	ENSLACP00000000628	ENSLACP00000017187	MutS homolog 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.989
LOC102360187	MUTYH	ENSLACP00000000628	ENSLACP00000023303	MutS homolog 2 (E. coli).	Uncharacterized protein.	0.543
LOC102360187	PCNA	ENSLACP00000000628	ENSLACP00000006575	MutS homolog 2 (E. coli).	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.963
LOC102360187	PMS1	ENSLACP00000000628	ENSLACP00000016464	MutS homolog 2 (E. coli).	PMS1 homolog 1, mismatch repair system component.	0.976