STRINGSTRING
TSC1 TSC1 LOC102367579 LOC102367579 RBM38 RBM38 THRAP3 THRAP3 DND1 DND1 STYX STYX DFFB DFFB WNT1 WNT1 CPTP CPTP CTSA CTSA LARP1 LARP1 TAF15 TAF15 NOP53 NOP53 YBX1 YBX1 TTC36 TTC36 TIGAR TIGAR UBXN1 UBXN1 TIRAP TIRAP DHX9 DHX9 PINK1 PINK1 ELAVL1 ELAVL1 RNF41 RNF41 FEZ2 FEZ2 TSPO TSPO PBK PBK ZCCHC17 ZCCHC17 EIF4ENIF1 EIF4ENIF1 LRIG2 LRIG2 MYD88 MYD88 IGF2BP1 IGF2BP1 GIPC1 GIPC1 MTOR MTOR H3BA08_LATCH H3BA08_LATCH TIMP2 TIMP2 FEZ1 FEZ1 DHX36 DHX36 H3B8U3_LATCH H3B8U3_LATCH NOCT NOCT BOLL BOLL TRAF5 TRAF5 HNRNPAB HNRNPAB GIPC3 GIPC3 N4BP1 N4BP1 USP14 USP14 SLC7A5 SLC7A5 TIMP3 TIMP3 ANGEL1 ANGEL1 DHX34 DHX34 TENT2 TENT2 SEC22B SEC22B LRPPRC LRPPRC DKC1 DKC1 TP53 TP53 NRDE2 NRDE2 MEIOC MEIOC TRDMT1 TRDMT1 H3AZY7_LATCH H3AZY7_LATCH ETFBKMT ETFBKMT TENT5B TENT5B GIPC2 GIPC2 LOC102359057 LOC102359057 IGF2BP3 IGF2BP3 MFSD2A MFSD2A OGT OGT RUBCN RUBCN STAT3 STAT3 LRRK2 LRRK2 TRAF3IP2 TRAF3IP2 ATP2B4 ATP2B4 PKP1 PKP1 IGF2BP2 IGF2BP2 PSEN1 PSEN1 RBM24 RBM24 MTMR9 MTMR9 TIMP4 TIMP4 TMEM39B TMEM39B SORL1 SORL1 RPL11 RPL11 TENT5C TENT5C UBQLN4 UBQLN4 LOC102367606 LOC102367606 CLEC16A CLEC16A BAG5 BAG5 TENT5A TENT5A LEP LEP H3ANP6_LATCH H3ANP6_LATCH TENT4B TENT4B H3AMJ7_LATCH H3AMJ7_LATCH SMCR8 SMCR8 SUFU SUFU CAMLG CAMLG SMG1 SMG1 A1CF A1CF TLK2 TLK2 LOC102351431 LOC102351431 LEPR LEPR UCHL5 UCHL5 E2F1 E2F1 SVIP SVIP GDNF GDNF MAPKAPK2 MAPKAPK2 KLHL40 KLHL40 HNRNPD HNRNPD LOC102366142 LOC102366142 LOC102346516 LOC102346516 EIF4G1 EIF4G1 IL10 IL10 FUS FUS NAF1 NAF1 VIP VIP LOC102345518 LOC102345518 LOC102365031 LOC102365031 PARN PARN POLDIP2 POLDIP2 NBAS NBAS FOXK2 FOXK2 LOC102358239 LOC102358239 USP7 USP7 PTPN3 PTPN3 BAG6 BAG6 WAC WAC FOXK1 FOXK1 TENT5D TENT5D DAZL DAZL SGTA SGTA NRBP2 NRBP2 RBM46 RBM46 LZTS1 LZTS1 LOC102361064 LOC102361064 LOC102357296 LOC102357296 GPLD1 GPLD1 ADRA1A ADRA1A SCFD1 SCFD1 TMEM39A TMEM39A HTR2B HTR2B PHAX PHAX DDRGK1 DDRGK1 WDR6 WDR6 H2ZTK9_LATCH H2ZTK9_LATCH TSC2 TSC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TSC1TSC complex subunit 1. (1217 aa)
LOC102367579Translocator protein 2. (163 aa)
RBM38RNA binding motif protein 38. (157 aa)
THRAP3Thyroid hormone receptor associated protein 3. (982 aa)
DND1DND microRNA-mediated repression inhibitor 1. (402 aa)
STYXSerine/threonine/tyrosine interacting protein. (222 aa)
DFFBDNA fragmentation factor subunit beta. (349 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
CPTPCeramide-1-phosphate transfer protein. (216 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (502 aa)
LARP1La ribonucleoprotein domain family member 1. (933 aa)
TAF15Uncharacterized protein. (460 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (399 aa)
YBX1Y-box binding protein 1. (305 aa)
TTC36Tetratricopeptide repeat domain 36. (216 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (212 aa)
UBXN1UBX domain protein 1. (320 aa)
TIRAPTIR domain containing adaptor protein. (267 aa)
DHX9DExH-box helicase 9. (1249 aa)
PINK1PTEN induced kinase 1. (467 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (355 aa)
RNF41Ring finger protein 41. (319 aa)
FEZ2Fasciculation and elongation protein zeta 2. (391 aa)
TSPOTranslocator protein. (164 aa)
PBKPDZ binding kinase. (336 aa)
ZCCHC17Zinc finger CCHC-type containing 17. (234 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (973 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1024 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
IGF2BP1Insulin-like growth factor 2 mRNA binding protein 1. (497 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
H3BA08_LATCHUncharacterized protein. (576 aa)
TIMP2TIMP metallopeptidase inhibitor 2. (221 aa)
FEZ1Fasciculation and elongation protein zeta 1. (393 aa)
DHX36DEAH-box helicase 36. (1001 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
NOCTNocturnin. (446 aa)
BOLLBoule homolog, RNA binding protein. (344 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (331 aa)
GIPC3GIPC PDZ domain containing family member 3. (319 aa)
N4BP1NEDD4 binding protein 1. (806 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (490 aa)
SLC7A5Solute carrier family 7 member 5. (522 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (216 aa)
ANGEL1Angel homolog 1. (498 aa)
DHX34DExH-box helicase 34. (989 aa)
TENT2Terminal nucleotidyltransferase 2. (496 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
LRPPRCLeucine-rich pentatricopeptide repeat containing. (1431 aa)
DKC1Dyskerin pseudouridine synthase 1. (506 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (825 aa)
MEIOCMeiosis specific with coiled-coil domain. (938 aa)
TRDMT1tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (382 aa)
H3AZY7_LATCHKelch-like family member 22. (628 aa)
ETFBKMTElectron transfer flavoprotein subunit beta lysine methyltransferase. (222 aa)
TENT5BUncharacterized protein. (394 aa)
GIPC2GIPC PDZ domain containing family member 2. (327 aa)
LOC102359057Uncharacterized protein. (103 aa)
IGF2BP3Insulin like growth factor 2 mRNA binding protein 3. (481 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (549 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1048 aa)
RUBCNRubicon autophagy regulator. (924 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
LRRK2Leucine rich repeat kinase 2. (2508 aa)
TRAF3IP2SEFIR domain-containing protein. (379 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1233 aa)
PKP1Plakophilin 1. (744 aa)
IGF2BP2Insulin like growth factor 2 mRNA binding protein 2. (547 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
RBM24RNA binding motif protein 24. (246 aa)
MTMR9Myotubularin related protein 9. (554 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (222 aa)
TMEM39BTransmembrane protein 39B. (487 aa)
SORL1Sortilin-related receptor, L(DLR class) A repeats containing. (1410 aa)
RPL11Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family. (184 aa)
TENT5CTerminal nucleotidyltransferase 5C. (400 aa)
UBQLN4Ubiquilin 4. (636 aa)
LOC102367606Carboxypeptidase; Belongs to the peptidase S10 family. (456 aa)
CLEC16AC-type lectin domain containing 16A. (610 aa)
BAG5BCL2 associated athanogene 5. (460 aa)
TENT5ATerminal nucleotidyltransferase 5A. (401 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
H3ANP6_LATCHUncharacterized protein; Belongs to the peptidase S10 family. (493 aa)
TENT4BTerminal nucleotidyltransferase 4B. (682 aa)
H3AMJ7_LATCHNbas_N domain-containing protein. (373 aa)
SMCR8SMCR8-C9orf72 complex subunit. (936 aa)
SUFUSUFU negative regulator of hedgehog signaling. (422 aa)
CAMLGCalcium modulating ligand. (307 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3451 aa)
A1CFAPOBEC1 complementation factor. (583 aa)
TLK2Tousled like kinase 2. (747 aa)
LOC102351431Uncharacterized protein. (229 aa)
LEPRLeptin receptor. (1149 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
E2F1E2F transcription factor 1. (411 aa)
SVIPSi:ch73-147o17.1. (80 aa)
GDNFGlial cell derived neurotrophic factor. (222 aa)
MAPKAPK2MAPK activated protein kinase 2. (332 aa)
KLHL40Kelch like family member 40. (599 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (309 aa)
LOC102366142Uncharacterized protein; Belongs to the synaptobrevin family. (216 aa)
LOC102346516Uncharacterized protein. (194 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1640 aa)
IL10Interleukin 10. (185 aa)
FUSFUS RNA binding protein. (532 aa)
NAF1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (315 aa)
VIPVasoactive intestinal peptide. (205 aa)
LOC102345518Death-associated protein. (104 aa)
LOC102365031ApaG domain-containing protein. (345 aa)
PARNPoly(A)-specific ribonuclease. (529 aa)
POLDIP2DNA polymerase delta interacting protein 2. (369 aa)
NBASNeuroblastoma amplified sequence. (1381 aa)
FOXK2Forkhead box K2. (499 aa)
LOC102358239TRAF3 interacting protein 2-like. (392 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1101 aa)
PTPN3Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (871 aa)
BAG6BCL2 associated athanogene 6. (995 aa)
WACWW domain containing adaptor with coiled-coil. (643 aa)
FOXK1Forkhead box K1. (673 aa)
TENT5DTerminal nucleotidyltransferase 5D. (395 aa)
DAZLRRM domain-containing protein. (300 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (316 aa)
NRBP2Nuclear receptor binding protein 2. (458 aa)
RBM46RNA binding motif protein 46. (534 aa)
LZTS1Leucine zipper tumor suppressor 1. (493 aa)
LOC102361064NTR domain-containing protein. (202 aa)
LOC102357296FPL domain-containing protein. (365 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (835 aa)
ADRA1AAdrenoceptor alpha 1A. (459 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (632 aa)
TMEM39ATransmembrane protein 39A. (318 aa)
HTR2B5-hydroxytryptamine receptor 2B. (474 aa)
PHAXPhosphorylated adaptor for RNA export. (404 aa)
DDRGK1DDRGK domain containing 1. (243 aa)
WDR6WD repeat domain 6. (1116 aa)
H2ZTK9_LATCHUncharacterized protein. (226 aa)
TSC2TSC complex subunit 2. (1836 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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