(22 nodes) Negative regulation of actin filament bundle assembly network (Latimeria chalumnae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MET	MET proto-oncogene, receptor tyrosine kinase. (1385 aa)
	CGNL1	Cingulin like 1. (1290 aa)
	ARHGAP6	Rho GTPase activating protein 6. (720 aa)
	WASF2	WASP family member 2. (503 aa)
	STMN1	Stathmin; Belongs to the stathmin family. (144 aa)
	H3BEF8_LATCH	Cytoplasmic linker associated protein 1a. (1413 aa)
	RHPN1	Rhophilin Rho GTPase binding protein 1. (606 aa)
	LOC102365550	Uncharacterized protein. (218 aa)
	CLASP1	Uncharacterized protein. (66 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1187 aa)
	CLASP2	Cytoplasmic linker associated protein 2. (1303 aa)
	TMEFF2	Transmembrane protein with EGF like and two follistatin like domains 2. (372 aa)
	RHPN2	Rhophilin Rho GTPase binding protein 2. (684 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (476 aa)
	LOC102366049	Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1052 aa)
	LOC102363797	Uncharacterized protein. (603 aa)
	MYOC	Myocilin. (272 aa)
	ARHGAP28	Rho GTPase activating protein 28. (691 aa)
	PHLDB2	Pleckstrin homology like domain family B member 2. (536 aa)
	LOC102347948	Uncharacterized protein. (290 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (1849 aa)
	PAK2	Non-specific serine/threonine protein kinase. (521 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CGNL1	LOC102366049	ENSLACP00000015353	ENSLACP00000008410	Cingulin like 1.	Rho/rac guanine nucleotide exchange factor (GEF) 18b.	0.418
CLASP2	PHLDB2	ENSLACP00000005846	ENSLACP00000011883	Cytoplasmic linker associated protein 2.	Pleckstrin homology like domain family B member 2.	0.563
LOC102347948	LOC102365550	ENSLACP00000001081	ENSLACP00000021954	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC102363797	SHANK3	ENSLACP00000008575	ENSLACP00000004784	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 3.	0.952
LOC102365550	LOC102347948	ENSLACP00000021954	ENSLACP00000001081	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC102366049	CGNL1	ENSLACP00000008410	ENSLACP00000015353	Rho/rac guanine nucleotide exchange factor (GEF) 18b.	Cingulin like 1.	0.418
LOC102366049	MET	ENSLACP00000008410	ENSLACP00000015263	Rho/rac guanine nucleotide exchange factor (GEF) 18b.	MET proto-oncogene, receptor tyrosine kinase.	0.538
MET	LOC102366049	ENSLACP00000015263	ENSLACP00000008410	MET proto-oncogene, receptor tyrosine kinase.	Rho/rac guanine nucleotide exchange factor (GEF) 18b.	0.538
MET	PAK2	ENSLACP00000015263	ENSLACP00000004711	MET proto-oncogene, receptor tyrosine kinase.	Non-specific serine/threonine protein kinase.	0.533
PAK2	MET	ENSLACP00000004711	ENSLACP00000015263	Non-specific serine/threonine protein kinase.	MET proto-oncogene, receptor tyrosine kinase.	0.533
PAK2	WASF2	ENSLACP00000004711	ENSLACP00000018313	Non-specific serine/threonine protein kinase.	WASP family member 2.	0.470
PHLDB2	CLASP2	ENSLACP00000011883	ENSLACP00000005846	Pleckstrin homology like domain family B member 2.	Cytoplasmic linker associated protein 2.	0.563
SHANK1	SHANK3	ENSLACP00000003891	ENSLACP00000004784	SH3 and multiple ankyrin repeat domains 1.	SH3 and multiple ankyrin repeat domains 3.	0.543
SHANK3	LOC102363797	ENSLACP00000004784	ENSLACP00000008575	SH3 and multiple ankyrin repeat domains 3.	Uncharacterized protein.	0.952
SHANK3	SHANK1	ENSLACP00000004784	ENSLACP00000003891	SH3 and multiple ankyrin repeat domains 3.	SH3 and multiple ankyrin repeat domains 1.	0.543
WASF2	PAK2	ENSLACP00000018313	ENSLACP00000004711	WASP family member 2.	Non-specific serine/threonine protein kinase.	0.470