(17 nodes) Regulation of mast cell activation network (Latimeria chalumnae)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	SYK	Tyrosine-protein kinase. (616 aa)
	H2ZSX8_LATCH	Fibronectin type-III domain-containing protein. (243 aa)
	RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1. (532 aa)
	LOC102354752	VPS9 domain-containing protein. (197 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
	H3AUL4_LATCH	Ig-like domain-containing protein. (268 aa)
	C12orf4	Chromosome 12 open reading frame 4. (552 aa)
	GATA1	GATA binding protein 1b. (432 aa)
	SNX4	Sorting nexin 4. (405 aa)
	H3AGM7_LATCH	Fibronectin type-III domain-containing protein. (234 aa)
	LYN	Tyrosine-protein kinase. (515 aa)
	FER	Protein kinase domain-containing protein. (157 aa)
	GAB2	GRB2 associated binding protein 2. (550 aa)
	BLK	Tyrosine-protein kinase. (447 aa)
	VAMP8	Vesicle associated membrane protein 8. (104 aa)
	H2ZZG8_LATCH	Tyrosine-protein kinase. (396 aa)
	PTPN6	Protein tyrosine phosphatase non-receptor type 6. (338 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLK	FER	ENSLACP00000003363	ENSLACP00000005632	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.405
BLK	FES	ENSLACP00000003363	ENSLACP00000017834	Tyrosine-protein kinase.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.405
BLK	H2ZZG8_LATCH	ENSLACP00000003363	ENSLACP00000002789	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.452
BLK	PTPN6	ENSLACP00000003363	ENSLACP00000002763	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 6.	0.411
BLK	SYK	ENSLACP00000003363	ENSLACP00000012982	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.510
FER	BLK	ENSLACP00000005632	ENSLACP00000003363	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.405
FER	H2ZZG8_LATCH	ENSLACP00000005632	ENSLACP00000002789	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.900
FES	BLK	ENSLACP00000017834	ENSLACP00000003363	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	Tyrosine-protein kinase.	0.405
GAB2	LYN	ENSLACP00000004478	ENSLACP00000006462	GRB2 associated binding protein 2.	Tyrosine-protein kinase.	0.436
GAB2	PTPN6	ENSLACP00000004478	ENSLACP00000002763	GRB2 associated binding protein 2.	Protein tyrosine phosphatase non-receptor type 6.	0.717
GAB2	SYK	ENSLACP00000004478	ENSLACP00000012982	GRB2 associated binding protein 2.	Tyrosine-protein kinase.	0.504
H2ZZG8_LATCH	BLK	ENSLACP00000002789	ENSLACP00000003363	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.452
H2ZZG8_LATCH	FER	ENSLACP00000002789	ENSLACP00000005632	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.900
H2ZZG8_LATCH	LYN	ENSLACP00000002789	ENSLACP00000006462	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.411
LOC102354752	RABGEF1	ENSLACP00000020287	ENSLACP00000021436	VPS9 domain-containing protein.	RAB guanine nucleotide exchange factor (GEF) 1.	0.648
LYN	GAB2	ENSLACP00000006462	ENSLACP00000004478	Tyrosine-protein kinase.	GRB2 associated binding protein 2.	0.436
LYN	H2ZZG8_LATCH	ENSLACP00000006462	ENSLACP00000002789	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.411
LYN	PTPN6	ENSLACP00000006462	ENSLACP00000002763	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 6.	0.787
LYN	SYK	ENSLACP00000006462	ENSLACP00000012982	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.909
PTPN6	BLK	ENSLACP00000002763	ENSLACP00000003363	Protein tyrosine phosphatase non-receptor type 6.	Tyrosine-protein kinase.	0.411