(11 nodes) Cholesterol efflux network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (521 aa)
	NPC2	NPC intracellular cholesterol transporter 2. (148 aa)
	ABCG1	ATP binding cassette subfamily G member 1. (649 aa)
	APOM	Apolipoprotein M. (194 aa)
	SPG11	SPG11 vesicle trafficking associated, spatacsin. (2438 aa)
	LOC102365332	Apolipoprotein Ea. (278 aa)
	APOA4	Apolipoprotein A4. (367 aa)
	ABCG8	ATP binding cassette subfamily G member 8. (677 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (438 aa)
	ABCG4	ATP binding cassette subfamily G member 4. (653 aa)
	APOB	Apolipoprotein B. (4644 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG1	ABCG5	ENSLACP00000004101	ENSLACP00000017950	ATP binding cassette subfamily G member 1.	ATP binding cassette subfamily G member 5.	0.848
ABCG4	ABCG5	ENSLACP00000020332	ENSLACP00000017950	ATP binding cassette subfamily G member 4.	ATP binding cassette subfamily G member 5.	0.836
ABCG5	ABCG1	ENSLACP00000017950	ENSLACP00000004101	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 1.	0.848
ABCG5	ABCG4	ENSLACP00000017950	ENSLACP00000020332	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 4.	0.836
ABCG5	ABCG8	ENSLACP00000017950	ENSLACP00000016915	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 8.	0.999
ABCG5	APOA4	ENSLACP00000017950	ENSLACP00000016757	ATP binding cassette subfamily G member 5.	Apolipoprotein A4.	0.415
ABCG5	APOB	ENSLACP00000017950	ENSLACP00000022987	ATP binding cassette subfamily G member 5.	Apolipoprotein B.	0.512
ABCG5	SCARB1	ENSLACP00000017950	ENSLACP00000023060	ATP binding cassette subfamily G member 5.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.420
ABCG8	ABCG5	ENSLACP00000016915	ENSLACP00000017950	ATP binding cassette subfamily G member 8.	ATP binding cassette subfamily G member 5.	0.999
ABCG8	APOB	ENSLACP00000016915	ENSLACP00000022987	ATP binding cassette subfamily G member 8.	Apolipoprotein B.	0.420
ABCG8	SCARB1	ENSLACP00000016915	ENSLACP00000023060	ATP binding cassette subfamily G member 8.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.418
APOA4	ABCG5	ENSLACP00000016757	ENSLACP00000017950	Apolipoprotein A4.	ATP binding cassette subfamily G member 5.	0.415
APOA4	APOB	ENSLACP00000016757	ENSLACP00000022987	Apolipoprotein A4.	Apolipoprotein B.	0.787
APOA4	APOM	ENSLACP00000016757	ENSLACP00000004816	Apolipoprotein A4.	Apolipoprotein M.	0.461
APOA4	LOC102365332	ENSLACP00000016757	ENSLACP00000016337	Apolipoprotein A4.	Apolipoprotein Ea.	0.860
APOB	ABCG5	ENSLACP00000022987	ENSLACP00000017950	Apolipoprotein B.	ATP binding cassette subfamily G member 5.	0.512
APOB	ABCG8	ENSLACP00000022987	ENSLACP00000016915	Apolipoprotein B.	ATP binding cassette subfamily G member 8.	0.420
APOB	APOA4	ENSLACP00000022987	ENSLACP00000016757	Apolipoprotein B.	Apolipoprotein A4.	0.787
APOB	LOC102365332	ENSLACP00000022987	ENSLACP00000016337	Apolipoprotein B.	Apolipoprotein Ea.	0.922
APOB	NPC2	ENSLACP00000022987	ENSLACP00000021312	Apolipoprotein B.	NPC intracellular cholesterol transporter 2.	0.695