(12 nodes) Regulation of heterotypic cell-cell adhesion network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2ZS97_LATCH	TNF_2 domain-containing protein. (143 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (259 aa)
	MYADM	Myeloid associated differentiation marker. (314 aa)
	IL10	Interleukin 10. (185 aa)
	FGG	Fibrinogen gamma chain. (376 aa)
	H3AEV1_LATCH	TNF_2 domain-containing protein. (230 aa)
	FGB	Fibrinogen beta chain. (454 aa)
	LOC102350832	Zgc:77748. (293 aa)
	MAP2K5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
	LOC102346019	C1q domain-containing protein. (226 aa)
	MBP	Myelin basic protein. (133 aa)
	THY1	Thy-1 cell surface antigen. (165 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	IL10	ENSLACP00000000452	ENSLACP00000005382	Adiponectin, C1Q and collagen domain containing.	Interleukin 10.	0.544
ADIPOQ	LOC102346019	ENSLACP00000000452	ENSLACP00000019134	Adiponectin, C1Q and collagen domain containing.	C1q domain-containing protein.	0.904
FGB	FGG	ENSLACP00000008521	ENSLACP00000007010	Fibrinogen beta chain.	Fibrinogen gamma chain.	0.999
FGB	MAP2K5	ENSLACP00000008521	ENSLACP00000014381	Fibrinogen beta chain.	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.	0.504
FGG	FGB	ENSLACP00000007010	ENSLACP00000008521	Fibrinogen gamma chain.	Fibrinogen beta chain.	0.999
H2ZS97_LATCH	IL10	ENSLACP00000000268	ENSLACP00000005382	TNF_2 domain-containing protein.	Interleukin 10.	0.405
H3AEV1_LATCH	IL10	ENSLACP00000008172	ENSLACP00000005382	TNF_2 domain-containing protein.	Interleukin 10.	0.405
IL10	ADIPOQ	ENSLACP00000005382	ENSLACP00000000452	Interleukin 10.	Adiponectin, C1Q and collagen domain containing.	0.544
IL10	H2ZS97_LATCH	ENSLACP00000005382	ENSLACP00000000268	Interleukin 10.	TNF_2 domain-containing protein.	0.405
IL10	H3AEV1_LATCH	ENSLACP00000005382	ENSLACP00000008172	Interleukin 10.	TNF_2 domain-containing protein.	0.405
IL10	LOC102346019	ENSLACP00000005382	ENSLACP00000019134	Interleukin 10.	C1q domain-containing protein.	0.470
LOC102346019	ADIPOQ	ENSLACP00000019134	ENSLACP00000000452	C1q domain-containing protein.	Adiponectin, C1Q and collagen domain containing.	0.904
LOC102346019	IL10	ENSLACP00000019134	ENSLACP00000005382	C1q domain-containing protein.	Interleukin 10.	0.470
MAP2K5	FGB	ENSLACP00000014381	ENSLACP00000008521	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.	Fibrinogen beta chain.	0.504