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CLCN1 CLCN1 GABRA2 GABRA2 GABRA4 GABRA4 PACC1 PACC1 CFTR CFTR GABRA5 GABRA5 GLRB GLRB BEST3 BEST3 GABRB3 GABRB3 H3A310_LATCH H3A310_LATCH GABRG3 GABRG3 CLIC3 CLIC3 ANO6 ANO6 BEST4 BEST4 GABRR1 GABRR1 LOC102362637 LOC102362637 CLCNKA CLCNKA H3AN19_LATCH H3AN19_LATCH BEST2 BEST2 GABRA3 GABRA3 GABRR2 GABRR2 CLIC1 CLIC1 GABRB1 GABRB1 GABRP GABRP TTYH1 TTYH1 CLCC1 CLCC1 CLCN7 CLCN7 GABRG2 GABRG2 CLIC4 CLIC4 H3B4F2_LATCH H3B4F2_LATCH GLRA3 GLRA3 CLIC6 CLIC6 GABRA6 GABRA6 TTYH3 TTYH3 CLIC2 CLIC2 GABRB2 GABRB2 GABRR3 GABRR3 GABRE GABRE BEST1 BEST1 GLRA4 GLRA4 TTYH2 TTYH2 GLRA1 GLRA1 GABRD GABRD CLIC5 CLIC5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLCN1Chloride voltage-gated channel 1. (821 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (380 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (562 aa)
PACC1Proton activated chloride channel 1. (357 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (454 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (498 aa)
BEST3Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (701 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (427 aa)
H3A310_LATCHGamma-aminobutyric acid type A receptor beta4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (407 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit. (223 aa)
CLIC3Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (239 aa)
ANO6Anoctamin. (766 aa)
BEST4Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (509 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (421 aa)
LOC102362637Chloride channel, voltage-sensitive 2b. (494 aa)
CLCNKAChloride channel protein. (686 aa)
H3AN19_LATCHChloride channel protein. (869 aa)
BEST2Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (291 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (398 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (493 aa)
CLIC1Chloride intracellular channel 1. (195 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (314 aa)
GABRPUncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
TTYH1Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (523 aa)
CLCC1Uncharacterized protein. (420 aa)
CLCN7Chloride channel protein. (802 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (476 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa)
H3B4F2_LATCHGamma-aminobutyric acid (GABA) A receptor, zeta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (446 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
CLIC6Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (544 aa)
TTYH3Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (523 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (251 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (401 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (478 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
BEST1Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (675 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (459 aa)
TTYH2Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (503 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (389 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (436 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (390 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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