STRINGSTRING
AKAP7 AKAP7 LOC102353789 LOC102353789 CNTD1 CNTD1 LOC102351466 LOC102351466 ADIPOQ ADIPOQ LOC102355203 LOC102355203 H2ZTT6_LATCH H2ZTT6_LATCH RNASEL RNASEL AZIN1 AZIN1 C2CD5 C2CD5 ATPSCKMT ATPSCKMT STIM2 STIM2 WNK4 WNK4 CLIP3 CLIP3 LOC102362749 LOC102362749 RAMP3 RAMP3 OSBPL8 OSBPL8 CACNG2 CACNG2 H3A068_LATCH H3A068_LATCH CFTR CFTR LOC102352528 LOC102352528 LRRC55 LRRC55 H3A2B0_LATCH H3A2B0_LATCH LOC102352804 LOC102352804 STAC STAC LOC102363383 LOC102363383 SHANK3 SHANK3 PKD2 PKD2 WNK3 WNK3 H3A6W7_LATCH H3A6W7_LATCH H3A855_LATCH H3A855_LATCH APLNR APLNR ATP1B3 ATP1B3 R3HDM1 R3HDM1 AMIGO3 AMIGO3 EDNRA EDNRA ANO6 ANO6 HTT HTT CHP1 CHP1 BAX BAX NDUFA4 NDUFA4 PDZK1 PDZK1 H3ADV1_LATCH H3ADV1_LATCH GPER1 GPER1 H3AF01_LATCH H3AF01_LATCH LOC102357829 LOC102357829 H3AHJ4_LATCH H3AHJ4_LATCH LRRC38 LRRC38 CDK5 CDK5 ACSL1 ACSL1 KCNQ1 KCNQ1 NFE2L2 NFE2L2 OPN3 OPN3 TESC TESC AKAP6 AKAP6 CACNG4 CACNG4 COA8 COA8 LOC102364622 LOC102364622 STIM1 STIM1 ACSL5 ACSL5 APPL1 APPL1 LOC102359041 LOC102359041 BRAF BRAF PSEN1 PSEN1 TRPC1 TRPC1 H3ATR2_LATCH H3ATR2_LATCH SLC1A2 SLC1A2 FGF19 FGF19 CACNB4 CACNB4 C1QTNF9 C1QTNF9 ADCYAP1R1 ADCYAP1R1 STAC2 STAC2 H3B1J8_LATCH H3B1J8_LATCH CLTRN CLTRN H3B1N5_LATCH H3B1N5_LATCH ACE2 ACE2 KCNE1 KCNE1 DRD4 DRD4 LOC102358762 LOC102358762 SLC7A5 SLC7A5 LOC102350639 LOC102350639 H3B845_LATCH H3B845_LATCH CAPN10 CAPN10 BAK1 BAK1 ABCC8 ABCC8 WNK2 WNK2 RNF207 RNF207 EDN1 EDN1 AMIGO1 AMIGO1 LOC102346019 LOC102346019 SLC17A8 SLC17A8 PINK1 PINK1 LOC102354490 LOC102354490 WNK1 WNK1 CAV3 CAV3 P2RX1 P2RX1 H3BGE9_LATCH H3BGE9_LATCH CREBL2 CREBL2 C1QTNF12 C1QTNF12 F2 F2 PLCG1 PLCG1 R3HDM2 R3HDM2 STAC3 STAC3 RELN RELN VMP1 VMP1 CHP2 CHP2 P2RX4 P2RX4 LOC102359410 LOC102359410 G6PD G6PD THY1 THY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKAP7A-kinase anchoring protein 7. (427 aa)
LOC102353789G_PROTEIN_RECEP_F1_2 domain-containing protein. (344 aa)
CNTD1Cyclin N-terminal domain containing 1. (274 aa)
LOC102351466Uncharacterized protein. (201 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (259 aa)
LOC102355203Na_H_Exchanger domain-containing protein. (161 aa)
H2ZTT6_LATCHPhosphoinositide phospholipase C. (404 aa)
RNASELUncharacterized protein. (698 aa)
AZIN1Antizyme inhibitor 1. (258 aa)
C2CD5C2 calcium dependent domain containing 5. (581 aa)
ATPSCKMTATP synthase c subunit lysine N-methyltransferase. (217 aa)
STIM2Stromal interaction molecule 2. (639 aa)
WNK4WNK lysine deficient protein kinase 4. (1163 aa)
CLIP3CAP-Gly domain containing linker protein 3. (536 aa)
LOC102362749Interfer-bind domain-containing protein. (265 aa)
RAMP3Receptor activity modifying protein 3. (117 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (855 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (225 aa)
H3A068_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein. (326 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
LOC102352528G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
LRRC55Leucine rich repeat containing 55. (283 aa)
H3A2B0_LATCHFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC102352804Phosphoinositide phospholipase C. (1172 aa)
STACSH3 and cysteine rich domain. (279 aa)
LOC102363383EF-hand domain-containing protein; Belongs to the S-100 family. (100 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1187 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
WNK3WNK lysine deficient protein kinase 3. (1769 aa)
H3A6W7_LATCHC2 domain-containing protein. (310 aa)
H3A855_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (320 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
R3HDM1R3H domain containing 1. (1107 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (510 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
ANO6Anoctamin. (766 aa)
HTTHuntingtin. (3125 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
BAXUncharacterized protein. (223 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (82 aa)
PDZK1PDZ domain containing 1. (523 aa)
H3ADV1_LATCHTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (974 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
H3AF01_LATCHUncharacterized protein. (658 aa)
LOC102357829G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (313 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
LRRC38Leucine rich repeat containing 38. (292 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (702 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (590 aa)
OPN3Opsin 3; Belongs to the G-protein coupled receptor 1 family. (155 aa)
TESCTescalcin. (218 aa)
AKAP6Uncharacterized protein. (901 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (329 aa)
COA8Cytochrome c oxidase assembly factor 8. (202 aa)
LOC102364622Si:dkey-190g11.3. (221 aa)
STIM1Stromal interaction molecule 1. (662 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (683 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (709 aa)
LOC102359041Zgc:153993. (208 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (768 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
H3ATR2_LATCHUncharacterized protein. (282 aa)
SLC1A2Amino acid transporter. (566 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
CACNB4Calcium channel, voltage-dependent, beta 4a subunit. (477 aa)
C1QTNF9C1q domain-containing protein. (198 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (337 aa)
STAC2SH3 and cysteine rich domain 2. (375 aa)
H3B1J8_LATCHAKAP7_NLS domain-containing protein. (240 aa)
CLTRNCollectrin domain-containing protein. (226 aa)
H3B1N5_LATCHOrn_DAP_Arg_deC domain-containing protein. (191 aa)
ACE2Angiotensin-converting enzyme. (814 aa)
KCNE1Uncharacterized protein. (122 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (382 aa)
LOC102358762Amino acid transporter. (538 aa)
SLC7A5Solute carrier family 7 member 5. (522 aa)
LOC102350639G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
H3B845_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (299 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (671 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
ABCC8ATP binding cassette subfamily C member 8. (1591 aa)
WNK2WNK lysine deficient protein kinase 2. (1994 aa)
RNF207Ring finger protein 207. (648 aa)
EDN1Endothelin 1. (216 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (506 aa)
LOC102346019C1q domain-containing protein. (226 aa)
SLC17A8Solute carrier family 17 member 8. (439 aa)
PINK1PTEN induced kinase 1. (467 aa)
LOC102354490Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (356 aa)
WNK1WNK lysine deficient protein kinase 1. (2654 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (403 aa)
H3BGE9_LATCHUncharacterized protein. (273 aa)
CREBL2cAMP responsive element binding protein like 2. (121 aa)
C1QTNF12C1q and TNF related 12. (265 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1219 aa)
R3HDM2R3H domain containing 2. (971 aa)
STAC3SH3 and cysteine rich domain 3. (373 aa)
RELNReelin. (3462 aa)
VMP1Vacuole membrane protein 1. (406 aa)
CHP2Calcineurin like EF-hand protein 2. (194 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
LOC102359410G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (387 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
THY1Thy-1 cell surface antigen. (165 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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