(88 nodes) Axoneme assembly network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MEIG1	Meiosis/spermiogenesis associated 1. (96 aa)
	H2ZTJ9_LATCH	ASH domain-containing protein. (708 aa)
	LOC102367224	Coiled-coil domain containing 114. (570 aa)
	H2ZWY0_LATCH	Uncharacterized protein. (156 aa)
	LOC102351981	Uncharacterized protein. (2928 aa)
	H2ZY45_LATCH	Uncharacterized protein. (177 aa)
	H2ZYG4_LATCH	Uncharacterized protein. (422 aa)
	DNAAF1	Dynein assembly factor 1, axonemal. (263 aa)
	H2ZYN0_LATCH	Uncharacterized protein. (1279 aa)
	SPEF2	Sperm flagellar 2. (1753 aa)
	H2ZZ85_LATCH	Uncharacterized protein. (1094 aa)
	DNAH5	Dynein axonemal heavy chain 5. (4680 aa)
	RSPH3	Radial spoke head 3. (317 aa)
	H3A0X7_LATCH	DUF4200 domain-containing protein. (548 aa)
	RSPH1	Radial spoke head component 1. (234 aa)
	DCX	Uncharacterized protein. (389 aa)
	WDR92	WD repeat domain 92. (692 aa)
	GAS8	Growth arrest specific 8. (482 aa)
	H3A2S4_LATCH	Uncharacterized protein. (431 aa)
	IQCG	IQ motif containing G. (391 aa)
	H3A6H3_LATCH	Cilia and flagella associated protein 206. (622 aa)
	DNAH2	Dynein axonemal heavy chain 2. (3683 aa)
	CFAP46	Uncharacterized protein. (401 aa)
	H3A9W8_LATCH	Uncharacterized protein. (541 aa)
	RP1L1	Uncharacterized protein. (1547 aa)
	TPGS1	Tubulin polyglutamylase complex subunit 1. (274 aa)
	STK36	Serine/threonine kinase 36. (1346 aa)
	H3ADM3_LATCH	Uncharacterized protein. (378 aa)
	H3ADY3_LATCH	NDK domain-containing protein. (351 aa)
	H3AE15_LATCH	Uncharacterized protein. (430 aa)
	CFAP43	Cilia and flagella associated protein 43. (1560 aa)
	HYDIN	Hydin_ADK domain-containing protein. (361 aa)
	H3AFN8_LATCH	Uncharacterized protein. (443 aa)
	CLUAP1	Clusterin associated protein 1. (348 aa)
	TTC25	Tetratricopeptide repeat domain 25. (578 aa)
	CFAP47	Uncharacterized protein. (922 aa)
	H3AKT4_LATCH	Uncharacterized protein. (128 aa)
	H3AN97_LATCH	Uncharacterized protein. (830 aa)
	EFCAB1	EF-hand calcium binding domain 1. (214 aa)
	TTC26	Tetratricopeptide repeat domain 26. (550 aa)
	DNAAF3	Uncharacterized protein. (484 aa)
	DNAL1	Dynein axonemal light chain 1. (192 aa)
	SPAG6	Sperm associated antigen 6. (477 aa)
	LRGUK	Leucine rich repeats and guanylate kinase domain containing. (595 aa)
	RSPH9	Radial spoke head 9 homolog. (277 aa)
	CCDC39	Coiled-coil domain containing 39. (945 aa)
	CFAP44	Cilia and flagella associated protein 44. (1295 aa)
	SPAG17	Sperm associated antigen 17. (2197 aa)
	H3AYJ5_LATCH	DUF4200 domain-containing protein. (561 aa)
	CEP131	Centrosomal protein 131. (1092 aa)
	CCDC103	Coiled-coil domain containing 103. (265 aa)
	MAATS1	MYCBP-associated, testis expressed 1. (766 aa)
	PIH1D3	PIH1 domain containing 3. (208 aa)
	DNAAF5	Dynein axonemal assembly factor 5. (844 aa)
	RP1	RP1 axonemal microtubule associated. (1901 aa)
	DNAAF4	Dynein axonemal assembly factor 4. (424 aa)
	BBS2	Bardet-Biedl syndrome 2 protein homolog. (724 aa)
	SPAG16	WD_REPEATS_REGION domain-containing protein. (608 aa)
	CCDC63	Uncharacterized protein. (561 aa)
	NEURL1	Neuralized E3 ubiquitin protein ligase 1. (568 aa)
	SPAG1	Sperm associated antigen 1. (924 aa)
	DNAAF2	Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. Belongs to the PIH1 family. Kintoun subfamily. (787 aa)
	CCDC151	Coiled-coil domain containing 151. (549 aa)
	H3B9H5_LATCH	Si:ch211-284k5.2. (203 aa)
	RSPH4A	Radial spoke head component 4A. (464 aa)
	CCDC65	Coiled-coil domain containing 65. (449 aa)
	CFAP157	Cilia and flagella associated protein 157. (534 aa)
	DRC1	Dynein regulatory complex subunit 1. (748 aa)
	H3BBP4_LATCH	Uncharacterized protein. (160 aa)
	TEKT2	Tektin 2. (430 aa)
	ZMYND10	Zinc finger MYND-type containing 10. (438 aa)
	DNAI2	Dynein axonemal intermediate chain 2. (565 aa)
	CCDC40	Coiled-coil domain containing 40. (859 aa)
	H3BFT5_LATCH	Tetratricopeptide repeat domain 12. (621 aa)
	H3BIP2_LATCH	Uncharacterized protein. (478 aa)
	H3BIP4_LATCH	ASH domain-containing protein. (750 aa)
	M3XGX9_LATCH	Uncharacterized protein. (185 aa)
	CFAP65	Cilia and flagella associated protein 65. (1806 aa)
	CFAP58	Cilia and flagella associated protein 58. (873 aa)
	CFAP97D1	Uncharacterized protein. (174 aa)
	C9orf116	Chromosome 9 open reading frame 116. (135 aa)
	DRC7	Dynein regulatory complex subunit 7. (812 aa)
	SPEF1	Sperm flagellar 1. (219 aa)
	TTLL1	Tubulin tyrosine ligase like 1. (423 aa)
	M3XKD2_LATCH	Uncharacterized protein. (783 aa)
	FOXJ1	Forkhead box J1. (452 aa)
	WDR78	WD repeat domain 78. (801 aa)
	ARMC2	Armadillo repeat containing 2. (567 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMC2	H3BBP4_LATCH	ENSLACP00000023379	ENSLACP00000019315	Armadillo repeat containing 2.	Uncharacterized protein.	0.922
ARMC2	SPEF2	ENSLACP00000023379	ENSLACP00000002608	Armadillo repeat containing 2.	Sperm flagellar 2.	0.466
BBS2	CLUAP1	ENSLACP00000017026	ENSLACP00000008605	Bardet-Biedl syndrome 2 protein homolog.	Clusterin associated protein 1.	0.557
BBS2	DNAAF4	ENSLACP00000017026	ENSLACP00000016875	Bardet-Biedl syndrome 2 protein homolog.	Dynein axonemal assembly factor 4.	0.446
BBS2	RP1L1	ENSLACP00000017026	ENSLACP00000006929	Bardet-Biedl syndrome 2 protein homolog.	Uncharacterized protein.	0.429
BBS2	SPAG1	ENSLACP00000017026	ENSLACP00000017964	Bardet-Biedl syndrome 2 protein homolog.	Sperm associated antigen 1.	0.403
BBS2	TTC25	ENSLACP00000017026	ENSLACP00000009762	Bardet-Biedl syndrome 2 protein homolog.	Tetratricopeptide repeat domain 25.	0.403
C9orf116	CCDC151	ENSLACP00000022519	ENSLACP00000018164	Chromosome 9 open reading frame 116.	Coiled-coil domain containing 151.	0.549
C9orf116	CCDC63	ENSLACP00000022519	ENSLACP00000017468	Chromosome 9 open reading frame 116.	Uncharacterized protein.	0.475
C9orf116	EFCAB1	ENSLACP00000022519	ENSLACP00000011500	Chromosome 9 open reading frame 116.	EF-hand calcium binding domain 1.	0.857
C9orf116	H3AFN8_LATCH	ENSLACP00000022519	ENSLACP00000008459	Chromosome 9 open reading frame 116.	Uncharacterized protein.	0.462
C9orf116	LOC102367224	ENSLACP00000022519	ENSLACP00000001724	Chromosome 9 open reading frame 116.	Coiled-coil domain containing 114.	0.475
C9orf116	TEKT2	ENSLACP00000022519	ENSLACP00000019678	Chromosome 9 open reading frame 116.	Tektin 2.	0.805
C9orf116	TTC25	ENSLACP00000022519	ENSLACP00000009762	Chromosome 9 open reading frame 116.	Tetratricopeptide repeat domain 25.	0.548
CCDC103	CCDC151	ENSLACP00000015091	ENSLACP00000018164	Coiled-coil domain containing 103.	Coiled-coil domain containing 151.	0.481
CCDC103	CCDC39	ENSLACP00000015091	ENSLACP00000013717	Coiled-coil domain containing 103.	Coiled-coil domain containing 39.	0.590
CCDC103	CCDC40	ENSLACP00000015091	ENSLACP00000020296	Coiled-coil domain containing 103.	Coiled-coil domain containing 40.	0.571
CCDC103	CCDC65	ENSLACP00000015091	ENSLACP00000019004	Coiled-coil domain containing 103.	Coiled-coil domain containing 65.	0.667
CCDC103	DNAAF1	ENSLACP00000015091	ENSLACP00000002439	Coiled-coil domain containing 103.	Dynein assembly factor 1, axonemal.	0.583
CCDC103	DNAAF3	ENSLACP00000015091	ENSLACP00000011692	Coiled-coil domain containing 103.	Uncharacterized protein.	0.588