(26 nodes) Synaptic transmission, glutamatergic network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRID1	Glutamate ionotropic receptor delta type subunit 1. (758 aa)
	H3AEI3_LATCH	Uncharacterized protein. (230 aa)
	ZZEF1	Zinc finger ZZ-type and EF-hand domain containing 1. (2945 aa)
	CLSTN3	Calsyntenin 3. (668 aa)
	GRID2	Glutamate receptor, ionotropic, delta 2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (371 aa)
	GRIK2	Glutamate ionotropic receptor kainate type subunit 2. (744 aa)
	CDH8	Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (713 aa)
	SLC17A6	Solute carrier family 17 member 6. (391 aa)
	CDK5	Cyclin dependent kinase 5. (290 aa)
	GRIK1	Glutamate ionotropic receptor kainate type subunit 1. (863 aa)
	UNC13C	Uncharacterized protein. (2038 aa)
	H3AR42_LATCH	Uncharacterized protein. (1639 aa)
	ALS2	Alsin Rho guanine nucleotide exchange factor ALS2. (1678 aa)
	GRIK5	Glutamate ionotropic receptor kainate type subunit 5. (795 aa)
	SLC17A7	MFS domain-containing protein. (560 aa)
	CACNB4	Calcium channel, voltage-dependent, beta 4a subunit. (477 aa)
	H3AZ47_LATCH	Uncharacterized protein. (107 aa)
	NAPA	NSF attachment protein alpha. (295 aa)
	UNC13A	Uncharacterized protein. (1646 aa)
	LOC102362407	Si:dkey-183j2.10; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (457 aa)
	NF1	Neurofibromin 1. (2814 aa)
	GRIK4	Glutamate ionotropic receptor kainate type subunit 4. (960 aa)
	LOC102346261	N-ethylmaleimide-sensitive factor attachment protein, beta b. (294 aa)
	SLC17A8	Solute carrier family 17 member 8. (439 aa)
	GRIK3	Glutamate ionotropic receptor kainate type subunit 3. (895 aa)
	P2RX1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (403 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH8	GRIK3	ENSLACP00000001253	ENSLACP00000020507	Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.	Glutamate ionotropic receptor kainate type subunit 3.	0.483
GRID2	H3AEI3_LATCH	ENSLACP00000001723	ENSLACP00000008054	Glutamate receptor, ionotropic, delta 2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Uncharacterized protein.	0.921
GRIK1	GRIK4	ENSLACP00000010506	ENSLACP00000006378	Glutamate ionotropic receptor kainate type subunit 1.	Glutamate ionotropic receptor kainate type subunit 4.	0.693
GRIK1	GRIK5	ENSLACP00000010506	ENSLACP00000013598	Glutamate ionotropic receptor kainate type subunit 1.	Glutamate ionotropic receptor kainate type subunit 5.	0.695
GRIK2	GRIK4	ENSLACP00000001584	ENSLACP00000006378	Glutamate ionotropic receptor kainate type subunit 2.	Glutamate ionotropic receptor kainate type subunit 4.	0.694
GRIK2	GRIK5	ENSLACP00000001584	ENSLACP00000013598	Glutamate ionotropic receptor kainate type subunit 2.	Glutamate ionotropic receptor kainate type subunit 5.	0.696
GRIK3	CDH8	ENSLACP00000020507	ENSLACP00000001253	Glutamate ionotropic receptor kainate type subunit 3.	Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.	0.483
GRIK3	GRIK4	ENSLACP00000020507	ENSLACP00000006378	Glutamate ionotropic receptor kainate type subunit 3.	Glutamate ionotropic receptor kainate type subunit 4.	0.696
GRIK3	GRIK5	ENSLACP00000020507	ENSLACP00000013598	Glutamate ionotropic receptor kainate type subunit 3.	Glutamate ionotropic receptor kainate type subunit 5.	0.699
GRIK4	GRIK1	ENSLACP00000006378	ENSLACP00000010506	Glutamate ionotropic receptor kainate type subunit 4.	Glutamate ionotropic receptor kainate type subunit 1.	0.693
GRIK4	GRIK2	ENSLACP00000006378	ENSLACP00000001584	Glutamate ionotropic receptor kainate type subunit 4.	Glutamate ionotropic receptor kainate type subunit 2.	0.694
GRIK4	GRIK3	ENSLACP00000006378	ENSLACP00000020507	Glutamate ionotropic receptor kainate type subunit 4.	Glutamate ionotropic receptor kainate type subunit 3.	0.696
GRIK5	GRIK1	ENSLACP00000013598	ENSLACP00000010506	Glutamate ionotropic receptor kainate type subunit 5.	Glutamate ionotropic receptor kainate type subunit 1.	0.695
GRIK5	GRIK2	ENSLACP00000013598	ENSLACP00000001584	Glutamate ionotropic receptor kainate type subunit 5.	Glutamate ionotropic receptor kainate type subunit 2.	0.696
GRIK5	GRIK3	ENSLACP00000013598	ENSLACP00000020507	Glutamate ionotropic receptor kainate type subunit 5.	Glutamate ionotropic receptor kainate type subunit 3.	0.699
H3AEI3_LATCH	GRID2	ENSLACP00000008054	ENSLACP00000001723	Uncharacterized protein.	Glutamate receptor, ionotropic, delta 2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.921
H3AR42_LATCH	SLC17A6	ENSLACP00000012113	ENSLACP00000000115	Uncharacterized protein.	Solute carrier family 17 member 6.	0.420
H3AR42_LATCH	SLC17A7	ENSLACP00000012113	ENSLACP00000013904	Uncharacterized protein.	MFS domain-containing protein.	0.420
H3AR42_LATCH	SLC17A8	ENSLACP00000012113	ENSLACP00000019961	Uncharacterized protein.	Solute carrier family 17 member 8.	0.420
SLC17A6	H3AR42_LATCH	ENSLACP00000000115	ENSLACP00000012113	Solute carrier family 17 member 6.	Uncharacterized protein.	0.420