STRINGSTRING
DEF6 DEF6 MTMR4 MTMR4 LRRC46 LRRC46 PPP1R15B PPP1R15B PPP1R36 PPP1R36 ENSA ENSA CHP2 CHP2 PPP1R17 PPP1R17 PPP4R4 PPP4R4 AMBRA1 AMBRA1 PPP6R3 PPP6R3 STYXL1 STYXL1 CRY2 CRY2 PPP1R26 PPP1R26 LRRC43 LRRC43 TGFB1 TGFB1 SPPL3 SPPL3 PPP2R3C PPP2R3C ANKLE2 ANKLE2 PINK1 PINK1 LOC102352268 LOC102352268 SYMPK SYMPK PPP1R2 PPP1R2 PLEK PLEK PPP1R1B PPP1R1B ROCK2 ROCK2 BOD1 BOD1 LOC106703879 LOC106703879 H3B6K7_LATCH H3B6K7_LATCH PPP1R16B PPP1R16B H3B4C9_LATCH H3B4C9_LATCH CMYA5 CMYA5 PDGFRB PDGFRB MTMR1 MTMR1 ROCK1 ROCK1 NSMF NSMF PTPA PTPA IGBP1 IGBP1 LPIN1 LPIN1 MAGI2 MAGI2 TSC1 TSC1 CNEP1R1 CNEP1R1 LOC102354453 LOC102354453 CDH5 CDH5 PPARGC1B PPARGC1B BAG4 BAG4 MTMR9 MTMR9 SMG5 SMG5 PPP6R2 PPP6R2 LOC102366200 LOC102366200 AGTR2 AGTR2 PPP1R7 PPP1R7 MGAT5 MGAT5 CDK5RAP3 CDK5RAP3 H3AEV1_LATCH H3AEV1_LATCH INPP5K INPP5K TMEM130 TMEM130 LTA LTA TGFB2 TGFB2 YWHAB YWHAB MTMR2 MTMR2 TIPRL TIPRL GBA GBA CHP1 CHP1 HTT HTT GNA12 GNA12 PPP1R42 PPP1R42 HSP90B1 HSP90B1 NUAK1 NUAK1 PPP1R8 PPP1R8 ARPP19 ARPP19 SEMA4D SEMA4D SMPD1 SMPD1 URI1 URI1 H3A214_LATCH H3A214_LATCH PTPRC PTPRC H2ZZW6_LATCH H2ZZW6_LATCH MTMR3 MTMR3 ITGA1 ITGA1 GPLD1 GPLD1 PPP6R1 PPP6R1 MASTL MASTL H2ZV40_LATCH H2ZV40_LATCH CSNK2B CSNK2B MFHAS1 MFHAS1 H2ZS97_LATCH H2ZS97_LATCH H2ZS19_LATCH H2ZS19_LATCH H2ZS17_LATCH H2ZS17_LATCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DEF6DEF6 guanine nucleotide exchange factor. (624 aa)
MTMR4Myotubularin related protein 4. (1171 aa)
LRRC46Leucine rich repeat containing 46. (441 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (703 aa)
PPP1R36Protein phosphatase 1 regulatory subunit 36. (427 aa)
ENSAEndosulfine alpha; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (118 aa)
CHP2Calcineurin like EF-hand protein 2. (194 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (106 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (864 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1195 aa)
PPP6R3Protein phosphatase 6 regulatory subunit 3. (912 aa)
STYXL1Serine/threonine/tyrosine interacting-like 1. (324 aa)
CRY2Cryptochrome circadian regulator 2. (434 aa)
PPP1R26PPP1R26_N domain-containing protein. (861 aa)
LRRC43Leucine rich repeat containing 43. (673 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
SPPL3Signal peptide peptidase like 3. (385 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (451 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (956 aa)
PINK1PTEN induced kinase 1. (467 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
SYMPKSymplekin. (1203 aa)
PPP1R2Uncharacterized protein. (211 aa)
PLEKPleckstrin. (353 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (121 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1462 aa)
BOD1Uncharacterized protein. (177 aa)
LOC106703879Uncharacterized protein. (178 aa)
H3B6K7_LATCHIKKbetaNEMObind domain-containing protein. (241 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (578 aa)
H3B4C9_LATCHPDZ domain-containing protein. (105 aa)
CMYA5Uncharacterized protein. (1165 aa)
PDGFRBPlatelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1103 aa)
MTMR1Myotubularin related protein 1. (669 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1350 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (524 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (360 aa)
IGBP1Immunoglobulin (CD79A) binding protein 1. (353 aa)
LPIN1Lipin 1. (938 aa)
MAGI2Uncharacterized protein. (397 aa)
TSC1TSC complex subunit 1. (1217 aa)
CNEP1R1CTD nuclear envelope phosphatase 1 regulatory subunit 1. (125 aa)
LOC102354453Uncharacterized protein. (230 aa)
CDH5Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
PPARGC1BPPARG coactivator 1 beta. (986 aa)
BAG4BCL2 associated athanogene 4. (454 aa)
MTMR9Myotubularin related protein 9. (554 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (1046 aa)
PPP6R2Protein phosphatase 6 regulatory subunit 2. (865 aa)
LOC102366200Uncharacterized protein; Belongs to the semaphorin family. (627 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
PPP1R7Protein phosphatase 1 regulatory subunit 7. (333 aa)
MGAT5Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (606 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (519 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (476 aa)
TMEM130Transmembrane protein 130. (417 aa)
LTALymphotoxin alpha. (166 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (244 aa)
MTMR2Myotubularin related protein 2. (711 aa)
TIPRLTOR signaling pathway regulator. (272 aa)
GBAGlucosylceramidase. (517 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
HTTHuntingtin. (3125 aa)
GNA12G protein subunit alpha 12. (382 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (252 aa)
HSP90B1Heat shock protein 90 beta family member 1. (800 aa)
NUAK1NUAK family kinase 1. (670 aa)
PPP1R8Protein phosphatase 1 regulatory subunit 8. (337 aa)
ARPP19cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (117 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
SMPD1Sphingomyelin phosphodiesterase 1. (396 aa)
URI1URI1 prefoldin like chaperone. (494 aa)
H3A214_LATCHUncharacterized protein. (559 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (830 aa)
H2ZZW6_LATCHProtein kinase domain-containing protein. (513 aa)
MTMR3Myotubularin related protein 3. (1222 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1185 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (835 aa)
PPP6R1Protein phosphatase 6 regulatory subunit 1. (724 aa)
MASTLMicrotubule associated serine/threonine kinase like. (880 aa)
H2ZV40_LATCHProtein kinase domain-containing protein. (266 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (148 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (635 aa)
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
H2ZS19_LATCHUncharacterized protein. (68 aa)
H2ZS17_LATCHCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (87 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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