(36 nodes) Protein localization to synapse network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KIF5C	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
	GRIP1	Glutamate receptor interacting protein 1. (938 aa)
	LRRC1	Uncharacterized protein. (155 aa)
	GRIPAP1	GRIP1 associated protein 1. (826 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1088 aa)
	CACNG2	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (225 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (1849 aa)
	GRIP2	Glutamate receptor interacting protein 2. (1064 aa)
	SNAP25	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
	LOC102349972	Uncharacterized protein. (246 aa)
	STAU2	Staufen double-stranded RNA binding protein 2. (689 aa)
	HSPB1	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (219 aa)
	LOC102363797	Uncharacterized protein. (603 aa)
	CLSTN1	Calsyntenin 1. (942 aa)
	KIF5B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (918 aa)
	CDK5	Cyclin dependent kinase 5. (290 aa)
	H3ALU1_LATCH	Uncharacterized protein. (1358 aa)
	NPTX2	Neuronal pentraxin 2. (444 aa)
	CACNG4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (329 aa)
	MPP4	Membrane palmitoylated protein 4; Belongs to the MAGUK family. (641 aa)
	H3AR28_LATCH	Uncharacterized protein. (1058 aa)
	LRRTM1	Leucine rich repeat transmembrane neuronal 1. (521 aa)
	SNAP47	Synaptosome associated protein 47. (424 aa)
	HOMER1	Homer scaffold protein 1. (367 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (828 aa)
	ADAM22	ADAM metallopeptidase domain 22. (728 aa)
	ZDHHC12	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (268 aa)
	BAIAP2	BAI1 associated protein 2. (434 aa)
	CACNG3	Calcium voltage-gated channel auxiliary subunit gamma 3. (246 aa)
	STAU1	Staufen double-stranded RNA binding protein 1. (723 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (928 aa)
	PCLO	Piccolo presynaptic cytomatrix protein. (4033 aa)
	LGI1	Leucine rich glioma inactivated 1. (456 aa)
	KIF5A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (971 aa)
	RELN	Reelin. (3462 aa)
	DLG3	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (901 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM22	DLG1	ENSLACP00000016604	ENSLACP00000018954	ADAM metallopeptidase domain 22.	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	0.628
ADAM22	DLG3	ENSLACP00000016604	ENSLACP00000022891	ADAM metallopeptidase domain 22.	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	0.628
ADAM22	DLG4	ENSLACP00000016604	ENSLACP00000015101	ADAM metallopeptidase domain 22.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.628
ADAM22	LGI1	ENSLACP00000016604	ENSLACP00000019371	ADAM metallopeptidase domain 22.	Leucine rich glioma inactivated 1.	0.720
ADAM22	LOC102349972	ENSLACP00000016604	ENSLACP00000004967	ADAM metallopeptidase domain 22.	Uncharacterized protein.	0.628
BAIAP2	LOC102363797	ENSLACP00000017063	ENSLACP00000008575	BAI1 associated protein 2.	Uncharacterized protein.	0.401
BAIAP2	SHANK1	ENSLACP00000017063	ENSLACP00000003891	BAI1 associated protein 2.	SH3 and multiple ankyrin repeat domains 1.	0.401
CDK5	GRIN2A	ENSLACP00000009607	ENSLACP00000002756	Cyclin dependent kinase 5.	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.420
DLG1	ADAM22	ENSLACP00000018954	ENSLACP00000016604	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	ADAM metallopeptidase domain 22.	0.628
DLG1	GRIN2A	ENSLACP00000018954	ENSLACP00000002756	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.725
DLG1	LOC102363797	ENSLACP00000018954	ENSLACP00000008575	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Uncharacterized protein.	0.645
DLG1	SHANK1	ENSLACP00000018954	ENSLACP00000003891	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 1.	0.645
DLG3	ADAM22	ENSLACP00000022891	ENSLACP00000016604	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	ADAM metallopeptidase domain 22.	0.628
DLG3	GRIN2A	ENSLACP00000022891	ENSLACP00000002756	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.725
DLG3	LOC102363797	ENSLACP00000022891	ENSLACP00000008575	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	Uncharacterized protein.	0.645
DLG3	SHANK1	ENSLACP00000022891	ENSLACP00000003891	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 1.	0.645
DLG4	ADAM22	ENSLACP00000015101	ENSLACP00000016604	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	ADAM metallopeptidase domain 22.	0.628
DLG4	GRIN2A	ENSLACP00000015101	ENSLACP00000002756	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.725
DLG4	LOC102363797	ENSLACP00000015101	ENSLACP00000008575	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Uncharacterized protein.	0.645
DLG4	SHANK1	ENSLACP00000015101	ENSLACP00000003891	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains 1.	0.645