(17 nodes) cAMP response element binding network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3AGM1_LATCH	Uncharacterized protein. (735 aa)
	H2ZRN5_LATCH	Uncharacterized protein. (172 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (495 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)
	H3ACZ6_LATCH	Uncharacterized protein. (158 aa)
	H3AD77_LATCH	JunE proto-oncogene, AP-1 transcription factor subunit. (316 aa)
	ATF6	Activating transcription factor 6. (355 aa)
	CREB3	cAMP responsive element binding protein 3. (452 aa)
	CREB3L2	cAMP responsive element binding protein 3 like 2. (408 aa)
	CREB3L3	cAMP responsive element binding protein 3 like 3. (329 aa)
	ATF7	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (481 aa)
	H3AY58_LATCH	BZIP domain-containing protein. (530 aa)
	LOC106703183	C2H2-type domain-containing protein. (189 aa)
	CREB5	cAMP responsive element binding protein 5. (288 aa)
	CREB1	cAMP responsive element binding protein 1. (347 aa)
	JDP2	Jun dimerization protein 2. (164 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (481 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	CREB1	ENSLACP00000005304	ENSLACP00000018100	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	cAMP responsive element binding protein 1.	0.413
ATF2	H3AD77_LATCH	ENSLACP00000005304	ENSLACP00000007598	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	JunE proto-oncogene, AP-1 transcription factor subunit.	0.844
ATF2	JDP2	ENSLACP00000005304	ENSLACP00000020575	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Jun dimerization protein 2.	0.406
ATF2	JUN	ENSLACP00000005304	ENSLACP00000005596	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.834
ATF2	LOC106703183	ENSLACP00000005304	ENSLACP00000015636	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	C2H2-type domain-containing protein.	0.453
ATF6	CREB3	ENSLACP00000008653	ENSLACP00000008681	Activating transcription factor 6.	cAMP responsive element binding protein 3.	0.502
ATF6	CREB3L1	ENSLACP00000008653	ENSLACP00000021137	Activating transcription factor 6.	cAMP responsive element binding protein 3 like 1.	0.564
ATF7	CREB1	ENSLACP00000013728	ENSLACP00000018100	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	cAMP responsive element binding protein 1.	0.413
ATF7	CREB5	ENSLACP00000013728	ENSLACP00000017246	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	cAMP responsive element binding protein 5.	0.430
ATF7	H3AD77_LATCH	ENSLACP00000013728	ENSLACP00000007598	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	JunE proto-oncogene, AP-1 transcription factor subunit.	0.816
ATF7	JDP2	ENSLACP00000013728	ENSLACP00000020575	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Jun dimerization protein 2.	0.712
ATF7	JUN	ENSLACP00000013728	ENSLACP00000005596	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.816
ATF7	LOC106703183	ENSLACP00000013728	ENSLACP00000015636	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	C2H2-type domain-containing protein.	0.453
CREB1	ATF2	ENSLACP00000018100	ENSLACP00000005304	cAMP responsive element binding protein 1.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.413
CREB1	ATF7	ENSLACP00000018100	ENSLACP00000013728	cAMP responsive element binding protein 1.	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	0.413
CREB1	CREB3	ENSLACP00000018100	ENSLACP00000008681	cAMP responsive element binding protein 1.	cAMP responsive element binding protein 3.	0.446
CREB1	CREB3L1	ENSLACP00000018100	ENSLACP00000021137	cAMP responsive element binding protein 1.	cAMP responsive element binding protein 3 like 1.	0.620
CREB1	CREB3L2	ENSLACP00000018100	ENSLACP00000009680	cAMP responsive element binding protein 1.	cAMP responsive element binding protein 3 like 2.	0.446
CREB1	CREB3L3	ENSLACP00000018100	ENSLACP00000010427	cAMP responsive element binding protein 1.	cAMP responsive element binding protein 3 like 3.	0.465
CREB1	H2ZRN5_LATCH	ENSLACP00000018100	ENSLACP00000000056	cAMP responsive element binding protein 1.	Uncharacterized protein.	0.413