(10 nodes) TORC1 signaling network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LARP1	La ribonucleoprotein domain family member 1. (933 aa)
	LOC102357296	FPL domain-containing protein. (365 aa)
	CARD11	Caspase recruitment domain family member 11. (1137 aa)
	CLEC16A	C-type lectin domain containing 16A. (610 aa)
	MFSD8	Major facilitator superfamily domain containing 8. (522 aa)
	H3B8U3_LATCH	Serine/threonine-protein kinase TOR. (1418 aa)
	MLST8	MTOR associated protein, LST8 homolog. (326 aa)
	RPTOR	Regulatory associated protein of MTOR complex 1. (1334 aa)
	MTOR	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
	NPRL3	NPR3 like, GATOR1 complex subunit. (396 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLEC16A	LOC102357296	ENSLACP00000011506	ENSLACP00000001890	C-type lectin domain containing 16A.	FPL domain-containing protein.	0.900
H3B8U3_LATCH	MLST8	ENSLACP00000018314	ENSLACP00000018842	Serine/threonine-protein kinase TOR.	MTOR associated protein, LST8 homolog.	0.974
H3B8U3_LATCH	MTOR	ENSLACP00000018314	ENSLACP00000018843	Serine/threonine-protein kinase TOR.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.944
H3B8U3_LATCH	NPRL3	ENSLACP00000018314	ENSLACP00000007869	Serine/threonine-protein kinase TOR.	NPR3 like, GATOR1 complex subunit.	0.666
H3B8U3_LATCH	RPTOR	ENSLACP00000018314	ENSLACP00000023161	Serine/threonine-protein kinase TOR.	Regulatory associated protein of MTOR complex 1.	0.979
LOC102357296	CLEC16A	ENSLACP00000001890	ENSLACP00000011506	FPL domain-containing protein.	C-type lectin domain containing 16A.	0.900
MLST8	H3B8U3_LATCH	ENSLACP00000018842	ENSLACP00000018314	MTOR associated protein, LST8 homolog.	Serine/threonine-protein kinase TOR.	0.974
MLST8	MTOR	ENSLACP00000018842	ENSLACP00000018843	MTOR associated protein, LST8 homolog.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.999
MLST8	NPRL3	ENSLACP00000018842	ENSLACP00000007869	MTOR associated protein, LST8 homolog.	NPR3 like, GATOR1 complex subunit.	0.780
MLST8	RPTOR	ENSLACP00000018842	ENSLACP00000023161	MTOR associated protein, LST8 homolog.	Regulatory associated protein of MTOR complex 1.	0.999
MTOR	H3B8U3_LATCH	ENSLACP00000018843	ENSLACP00000018314	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.944
MTOR	MLST8	ENSLACP00000018843	ENSLACP00000018842	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	MTOR associated protein, LST8 homolog.	0.999
MTOR	NPRL3	ENSLACP00000018843	ENSLACP00000007869	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	NPR3 like, GATOR1 complex subunit.	0.666
MTOR	RPTOR	ENSLACP00000018843	ENSLACP00000023161	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Regulatory associated protein of MTOR complex 1.	0.997
NPRL3	H3B8U3_LATCH	ENSLACP00000007869	ENSLACP00000018314	NPR3 like, GATOR1 complex subunit.	Serine/threonine-protein kinase TOR.	0.666
NPRL3	MLST8	ENSLACP00000007869	ENSLACP00000018842	NPR3 like, GATOR1 complex subunit.	MTOR associated protein, LST8 homolog.	0.780
NPRL3	MTOR	ENSLACP00000007869	ENSLACP00000018843	NPR3 like, GATOR1 complex subunit.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.666
NPRL3	RPTOR	ENSLACP00000007869	ENSLACP00000023161	NPR3 like, GATOR1 complex subunit.	Regulatory associated protein of MTOR complex 1.	0.819
RPTOR	H3B8U3_LATCH	ENSLACP00000023161	ENSLACP00000018314	Regulatory associated protein of MTOR complex 1.	Serine/threonine-protein kinase TOR.	0.979
RPTOR	MLST8	ENSLACP00000023161	ENSLACP00000018842	Regulatory associated protein of MTOR complex 1.	MTOR associated protein, LST8 homolog.	0.999