(5 nodes) MHC class I peptide loading complex network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TAP1	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (735 aa)
	PDIA3	Protein disulfide-isomerase. (497 aa)
	TAPBP	Uncharacterized protein. (453 aa)
	TAP2	Transporter associated with antigen processing, subunit type a. (720 aa)
	ABCB9	ATP binding cassette subfamily B member 9. (779 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB9	PDIA3	ENSLACP00000020226	ENSLACP00000015133	ATP binding cassette subfamily B member 9.	Protein disulfide-isomerase.	0.538
ABCB9	TAP2	ENSLACP00000020226	ENSLACP00000015839	ATP binding cassette subfamily B member 9.	Transporter associated with antigen processing, subunit type a.	0.984
ABCB9	TAPBP	ENSLACP00000020226	ENSLACP00000010397	ATP binding cassette subfamily B member 9.	Uncharacterized protein.	0.788
PDIA3	ABCB9	ENSLACP00000015133	ENSLACP00000020226	Protein disulfide-isomerase.	ATP binding cassette subfamily B member 9.	0.538
PDIA3	TAP1	ENSLACP00000015133	ENSLACP00000016040	Protein disulfide-isomerase.	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	0.951
PDIA3	TAP2	ENSLACP00000015133	ENSLACP00000015839	Protein disulfide-isomerase.	Transporter associated with antigen processing, subunit type a.	0.962
PDIA3	TAPBP	ENSLACP00000015133	ENSLACP00000010397	Protein disulfide-isomerase.	Uncharacterized protein.	0.997
TAP1	PDIA3	ENSLACP00000016040	ENSLACP00000015133	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	Protein disulfide-isomerase.	0.951
TAP1	TAP2	ENSLACP00000016040	ENSLACP00000015839	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	Transporter associated with antigen processing, subunit type a.	0.998
TAP1	TAPBP	ENSLACP00000016040	ENSLACP00000010397	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	Uncharacterized protein.	0.955
TAP2	ABCB9	ENSLACP00000015839	ENSLACP00000020226	Transporter associated with antigen processing, subunit type a.	ATP binding cassette subfamily B member 9.	0.984
TAP2	PDIA3	ENSLACP00000015839	ENSLACP00000015133	Transporter associated with antigen processing, subunit type a.	Protein disulfide-isomerase.	0.962
TAP2	TAP1	ENSLACP00000015839	ENSLACP00000016040	Transporter associated with antigen processing, subunit type a.	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	0.998
TAP2	TAPBP	ENSLACP00000015839	ENSLACP00000010397	Transporter associated with antigen processing, subunit type a.	Uncharacterized protein.	0.971
TAPBP	ABCB9	ENSLACP00000010397	ENSLACP00000020226	Uncharacterized protein.	ATP binding cassette subfamily B member 9.	0.788
TAPBP	PDIA3	ENSLACP00000010397	ENSLACP00000015133	Uncharacterized protein.	Protein disulfide-isomerase.	0.997
TAPBP	TAP1	ENSLACP00000010397	ENSLACP00000016040	Uncharacterized protein.	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	0.955
TAPBP	TAP2	ENSLACP00000010397	ENSLACP00000015839	Uncharacterized protein.	Transporter associated with antigen processing, subunit type a.	0.971