STRINGSTRING
GRIN3A GRIN3A UNC5C UNC5C H3ABV0_LATCH H3ABV0_LATCH SORBS2 SORBS2 FXR2 FXR2 H3ABK5_LATCH H3ABK5_LATCH LOC102355547 LOC102355547 DNER DNER KCNN2 KCNN2 PRKAA2 PRKAA2 GNA12 GNA12 GPM6A GPM6A H3A9B7_LATCH H3A9B7_LATCH SLC5A7 SLC5A7 S100B S100B AMIGO3 AMIGO3 FMR1 FMR1 LOC102345511 LOC102345511 FBXW11 FBXW11 SCN1B SCN1B SHANK2 SHANK2 SNCG SNCG CRTC1 CRTC1 H3A6C4_LATCH H3A6C4_LATCH KCNE3 KCNE3 RET RET SEZ6L2 SEZ6L2 EPM2A EPM2A VIP VIP P2RX3 P2RX3 PJVK PJVK SYT11 SYT11 PDE1B PDE1B SOS1 SOS1 PLXDC1 PLXDC1 C9orf72 C9orf72 BRD1 BRD1 CRMP1 CRMP1 CNKSR2 CNKSR2 H3A2T1_LATCH H3A2T1_LATCH PRKAA1 PRKAA1 H3A2S1_LATCH H3A2S1_LATCH GABRA5 GABRA5 LOC102362583 LOC102362583 TXN2 TXN2 ZNF385A ZNF385A OPRD1 OPRD1 CD200 CD200 PNOC PNOC UNC5A UNC5A LOC102364345 LOC102364345 H2ZZI1_LATCH H2ZZI1_LATCH H2ZZF8_LATCH H2ZZF8_LATCH GAP43 GAP43 SLC6A3 SLC6A3 SLC4A10 SLC4A10 H2ZY86_LATCH H2ZY86_LATCH LOC102345919 LOC102345919 KLHL35 KLHL35 SLC1A3 SLC1A3 P2RX6 P2RX6 SRR SRR H2ZWQ4_LATCH H2ZWQ4_LATCH PTBP2 PTBP2 GABRA2 GABRA2 APP APP H2ZW26_LATCH H2ZW26_LATCH KCNK2 KCNK2 ROR2 ROR2 H2ZVQ7_LATCH H2ZVQ7_LATCH NGFR NGFR ANXA3 ANXA3 LOC102355825 LOC102355825 KCNC2 KCNC2 PDYN PDYN GRIP1 GRIP1 H2ZSK8_LATCH H2ZSK8_LATCH LOC102357872 LOC102357872 ERMN ERMN SEZ6L SEZ6L ELK1 ELK1 RTN4RL1 RTN4RL1 AKAP12 AKAP12 NMNAT3 NMNAT3 NRSN2 NRSN2 VGF VGF KCNK1 KCNK1 STAU2 STAU2 KLHL14 KLHL14 DCTN1 DCTN1 PCSK1 PCSK1 LOC102348601 LOC102348601 ENC1 ENC1 LOC102351543 LOC102351543 MAP2 MAP2 CREB3 CREB3 KCNB2 KCNB2 RUFY3 RUFY3 H3AHE4_LATCH H3AHE4_LATCH H3AHJ4_LATCH H3AHJ4_LATCH OPN4 OPN4 CDK5 CDK5 LOC102351896 LOC102351896 TNN TNN KCNQ1 KCNQ1 BRINP3 BRINP3 RTN4R RTN4R H3AKB9_LATCH H3AKB9_LATCH IL6ST IL6ST XRN1 XRN1 PDE1C PDE1C RAPGEF2 RAPGEF2 H3AM63_LATCH H3AM63_LATCH ADNP ADNP MAP1A MAP1A SDC2 SDC2 FBXO31 FBXO31 TMEM266 TMEM266 MPP5 MPP5 LOC102361814 LOC102361814 UCN UCN OMP OMP MAPK8IP2 MAPK8IP2 CRIPT CRIPT KNDC1 KNDC1 SHTN1 SHTN1 ADCY8 ADCY8 H3AQM3_LATCH H3AQM3_LATCH KCND1 KCND1 LOC102362689 LOC102362689 LOC102355555 LOC102355555 TTLL7 TTLL7 PMM1 PMM1 PSEN1 PSEN1 NUMA1 NUMA1 FXR1 FXR1 H3AT83_LATCH H3AT83_LATCH FZD3 FZD3 PDE11A PDE11A TMEM100 TMEM100 DTNBP1 DTNBP1 VTI1A VTI1A CRHBP CRHBP LRRK2 LRRK2 SNAP47 SNAP47 LOC102350473 LOC102350473 SNCA SNCA KCNN1 KCNN1 SERPINI1 SERPINI1 BRINP1 BRINP1 H3AYC1_LATCH H3AYC1_LATCH CPLX2 CPLX2 HOMER1 HOMER1 ROGDI ROGDI KCND2-2 KCND2-2 NSMF NSMF H3AZY1_LATCH H3AZY1_LATCH SYT4 SYT4 MYO10 MYO10 PAM PAM TRPM2 TRPM2 H3B0I4_LATCH H3B0I4_LATCH HPN HPN ZNF804A ZNF804A CNTN2 CNTN2 KCNC1 KCNC1 ZC4H2 ZC4H2 SLC6A2 SLC6A2 RBM8A RBM8A ITGA4 ITGA4 ZPR1 ZPR1 CYGB CYGB MAP1B MAP1B BAIAP2 BAIAP2 RACK1 RACK1 TANC1 TANC1 PRPH PRPH RIC3 RIC3 KCND2 KCND2 KREMEN1 KREMEN1 KCNN3 KCNN3 STMN2 STMN2 TMEM50A TMEM50A NEURL1 NEURL1 NCDN NCDN ATP13A2 ATP13A2 CYFIP1 CYFIP1 SNCB SNCB PPP1R1B PPP1R1B STAU1 STAU1 DHX36 DHX36 FEZ1 FEZ1 CIB1 CIB1 KCNB1 KCNB1 TXNRD2 TXNRD2 DBNL DBNL FLRT1 FLRT1 AMIGO1 AMIGO1 KLHL24 KLHL24 ADCYAP1 ADCYAP1 KLHL6 KLHL6 DRP2 DRP2 PSEN2 PSEN2 TBX21 TBX21 NCF1 NCF1 ATOH7 ATOH7 SLC17A8 SLC17A8 EFHC1 EFHC1 VTI1B VTI1B HOMER2 HOMER2 CIB3 CIB3 G3BP1 G3BP1 LOC102363355 LOC102363355 TOP1 TOP1 PAFAH1B1 PAFAH1B1 KCNC4 KCNC4 H3BFU5_LATCH H3BFU5_LATCH LRP6 LRP6 KCND3 KCND3 NRGN NRGN H3BGI5_LATCH H3BGI5_LATCH GRIA1 GRIA1 CIT CIT MAPK8IP1 MAPK8IP1 TMPRSS5 TMPRSS5 DIXDC1 DIXDC1 SLC4A8 SLC4A8 SLC6A1 SLC6A1 RIN3 RIN3 DIP2B DIP2B GABRD GABRD MBP MBP MUL1 MUL1 LOC102355574 LOC102355574 MCRS1 MCRS1 DENND1A DENND1A INPP5F INPP5F GRIN3B GRIN3B APOD APOD P2RX4 P2RX4 APOB APOB LOC102345237 LOC102345237 LOC102347127 LOC102347127 PDE1A PDE1A LOC102350310 LOC102350310 TNFRSF1B TNFRSF1B MAP2K4 MAP2K4 LOC102352322 LOC102352322 M3XLM0_LATCH M3XLM0_LATCH KCNJ14 KCNJ14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1109 aa)
UNC5CUnc-5 netrin receptor C. (754 aa)
H3ABV0_LATCHTyrosine hydroxylase. (247 aa)
SORBS2Sorbin and SH3 domain containing 2. (1442 aa)
FXR2FMR1 autosomal homolog 2. (599 aa)
H3ABK5_LATCHProtein kinase domain-containing protein. (360 aa)
LOC102355547MACPF domain-containing protein. (689 aa)
DNERDelta/notch like EGF repeat containing. (644 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (748 aa)
PRKAA2Non-specific serine/threonine protein kinase. (553 aa)
GNA12G protein subunit alpha 12. (382 aa)
GPM6AGlycoprotein M6A. (298 aa)
H3A9B7_LATCHUncharacterized protein. (521 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (579 aa)
S100BS100 calcium binding protein B; Belongs to the S-100 family. (114 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (510 aa)
FMR1Fragile X mental retardation 1. (627 aa)
LOC102345511Uncharacterized protein. (292 aa)
FBXW11F-box and WD repeat domain containing 11. (529 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (221 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1161 aa)
SNCGGamma-synuclein; Belongs to the synuclein family. (130 aa)
CRTC1CREB regulated transcription coactivator 1. (615 aa)
H3A6C4_LATCHUncharacterized protein. (157 aa)
KCNE3Uncharacterized protein. (92 aa)
RETRet proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1090 aa)
SEZ6L2Seizure related 6 homolog like 2. (870 aa)
EPM2AEPM2A glucan phosphatase, laforin. (228 aa)
VIPVasoactive intestinal peptide. (205 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
PJVKPejvakin. (355 aa)
SYT11Synaptotagmin 11. (429 aa)
PDE1BPhosphodiesterase. (469 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1331 aa)
PLXDC1Plexin domain containing 1. (501 aa)
C9orf72C9orf72-SMCR8 complex subunit. (482 aa)
BRD1Bromodomain containing 1. (1190 aa)
CRMP1Collapsin response mediator protein 1. (659 aa)
CNKSR2Connector enhancer of kinase suppressor of Ras 2. (805 aa)
H3A2T1_LATCHUncharacterized protein. (573 aa)
PRKAA1Non-specific serine/threonine protein kinase. (552 aa)
H3A2S1_LATCHBTB domain-containing protein. (180 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (454 aa)
LOC102362583Phosphodiesterase. (865 aa)
TXN2Thioredoxin 2. (162 aa)
ZNF385AZinc finger protein 385A. (403 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (376 aa)
CD200Uncharacterized protein. (224 aa)
PNOCPrepronociceptin a. (244 aa)
UNC5AUnc-5 netrin receptor A. (798 aa)
LOC102364345Ectodermal-neural cortex 3. (589 aa)
H2ZZI1_LATCHRING-type domain-containing protein. (424 aa)
H2ZZF8_LATCHRecoverin 3. (164 aa)
GAP43Growth associated protein 43. (201 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (624 aa)
SLC4A10Anion exchange protein. (1097 aa)
H2ZY86_LATCHPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (177 aa)
LOC102345919Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (566 aa)
KLHL35Kelch like family member 35. (600 aa)
SLC1A3Amino acid transporter. (441 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (419 aa)
SRRSerine racemase. (337 aa)
H2ZWQ4_LATCHIg-like domain-containing protein. (175 aa)
PTBP2Polypyrimidine tract binding protein 2. (535 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (380 aa)
APPAmyloid beta precursor protein. (652 aa)
H2ZW26_LATCHUncharacterized protein. (352 aa)
KCNK2Potassium two pore domain channel subfamily K member 2. (280 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (882 aa)
H2ZVQ7_LATCHPeptidase_S8 domain-containing protein. (135 aa)
NGFRNerve growth factor receptor. (197 aa)
ANXA3Annexin. (323 aa)
LOC102355825Opsin 4xa; Belongs to the G-protein coupled receptor 1 family. (260 aa)
KCNC2Ion_trans domain-containing protein; Belongs to the potassium channel family. (322 aa)
PDYNProdynorphin. (232 aa)
GRIP1Glutamate receptor interacting protein 1. (938 aa)
H2ZSK8_LATCHTYR_PHOSPHATASE_2 domain-containing protein. (101 aa)
LOC102357872Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (229 aa)
ERMNUncharacterized protein. (114 aa)
SEZ6LSeizure related 6 homolog like. (776 aa)
ELK1ETS transcription factor ELK1. (520 aa)
RTN4RL1Reticulon 4 receptor like 1. (463 aa)
AKAP12A-kinase anchoring protein 12. (1381 aa)
NMNAT3Nicotinamide-nucleotide adenylyltransferase. (290 aa)
NRSN2Neurensin 2. (193 aa)
VGFVGF nerve growth factor inducible. (438 aa)
KCNK1Potassium channel subfamily K member. (340 aa)
STAU2Staufen double-stranded RNA binding protein 2. (689 aa)
KLHL14Kelch like family member 14. (608 aa)
DCTN1Dynactin 1a. (1139 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (662 aa)
LOC102348601Solute carrier family 2 member 3a; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
ENC1Ectodermal-neural cortex 1. (591 aa)
LOC102351543Aa_trans domain-containing protein. (253 aa)
MAP2Microtubule-associated protein. (1361 aa)
CREB3cAMP responsive element binding protein 3. (452 aa)
KCNB2Ion_trans domain-containing protein; Belongs to the potassium channel family. (714 aa)
RUFY3RUN and FYVE domain containing 3. (715 aa)
H3AHE4_LATCHUncharacterized protein. (463 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
OPN4Opsin 4. (517 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
LOC102351896RGS domain-containing protein. (184 aa)
TNNTenascin N. (831 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
RTN4RReticulon 4 receptor. (472 aa)
H3AKB9_LATCHUncharacterized protein. (498 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
XRN15'-3' exoribonuclease 1. (1737 aa)
PDE1CPhosphodiesterase. (440 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1514 aa)
H3AM63_LATCHAa_trans domain-containing protein. (408 aa)
ADNPActivity dependent neuroprotector homeobox. (1116 aa)
MAP1AMicrotubule associated protein 1A. (2331 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (209 aa)
FBXO31F-box protein 31. (594 aa)
TMEM266Transmembrane protein 266. (379 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (678 aa)
LOC102361814Tudor domain-containing protein. (304 aa)
UCNUrocortin. (167 aa)
OMPOlfactory marker protein. (159 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (992 aa)
CRIPTCXXC repeat containing interactor of PDZ3 domain. (101 aa)
KNDC1Uncharacterized protein. (1728 aa)
SHTN1Shootin 1. (403 aa)
ADCY8AC_N domain-containing protein. (266 aa)
H3AQM3_LATCHAa_trans domain-containing protein. (401 aa)
KCND1Potassium voltage-gated channel, Shal-related subfamily, member 1; Belongs to the potassium channel family. (636 aa)
LOC102362689Microtubule-associated protein 1Sb. (1334 aa)
LOC102355555Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2012 aa)
TTLL7Tubulin tyrosine ligase like 7. (907 aa)
PMM1Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (259 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2155 aa)
FXR1FMR1 autosomal homolog 1. (679 aa)
H3AT83_LATCHSAC domain-containing protein. (359 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (604 aa)
PDE11APhosphodiesterase. (574 aa)
TMEM100Transmembrane protein 100. (134 aa)
DTNBP1Dystrobrevin binding protein 1. (355 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (214 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (323 aa)
LRRK2Leucine rich repeat kinase 2. (2508 aa)
SNAP47Synaptosome associated protein 47. (424 aa)
LOC102350473Tyrosine hydroxylase 2. (425 aa)
SNCAGamma-synuclein; Belongs to the synuclein family. (103 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (563 aa)
SERPINI1Serpin family I member 1; Belongs to the serpin family. (409 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (689 aa)
H3AYC1_LATCHUncharacterized protein. (301 aa)
CPLX2Complexin 2. (134 aa)
HOMER1Homer scaffold protein 1. (367 aa)
ROGDIRogdi atypical leucine zipper. (307 aa)
KCND2-2Uncharacterized protein; Belongs to the potassium channel family. (260 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (524 aa)
H3AZY1_LATCHUncharacterized protein. (389 aa)
SYT4Synaptotagmin 4. (434 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1542 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (960 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1473 aa)
H3B0I4_LATCHSi:ch73-263o4.3. (320 aa)
HPNHepsin; Belongs to the peptidase S1 family. (415 aa)
ZNF804AZinc finger protein 804A. (1127 aa)
CNTN2Contactin 2. (1026 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (511 aa)
ZC4H2Zinc finger C4H2-type containing. (188 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (639 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (177 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1037 aa)
ZPR1ZPR1 zinc finger. (470 aa)
CYGBCytoglobin; Belongs to the globin family. (179 aa)
MAP1BMicrotubule associated protein 1B. (2174 aa)
BAIAP2BAI1 associated protein 2. (434 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
TANC1Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1815 aa)
PRPHPeripherin; Belongs to the intermediate filament family. (229 aa)
RIC3RIC3 acetylcholine receptor chaperone. (373 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (371 aa)
KREMEN1Kringle containing transmembrane protein 1. (249 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (680 aa)
STMN2Stathmin; Belongs to the stathmin family. (179 aa)
TMEM50ATransmembrane protein 50A. (159 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (568 aa)
NCDNNeurochondrin. (683 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1091 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1259 aa)
SNCBBeta-synuclein; Belongs to the synuclein family. (133 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (121 aa)
STAU1Staufen double-stranded RNA binding protein 1. (723 aa)
DHX36DEAH-box helicase 36. (1001 aa)
FEZ1Fasciculation and elongation protein zeta 1. (393 aa)
CIB1Calcium and integrin binding 1. (190 aa)
KCNB1Potassium voltage-gated channel, Shab-related subfamily, member 1; Belongs to the potassium channel family. (677 aa)
TXNRD2Thioredoxin reductase 2. (512 aa)
DBNLDrebrin like. (512 aa)
FLRT1Fibronectin leucine rich transmembrane protein 1. (648 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (506 aa)
KLHL24Kelch like family member 24. (596 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (199 aa)
KLHL6Kelch like family member 6. (613 aa)
DRP2Dystrophin related protein 2. (851 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
TBX21T-box transcription factor 21. (570 aa)
NCF1Neutrophil cytosolic factor 1. (416 aa)
ATOH7Atonal bHLH transcription factor 7. (151 aa)
SLC17A8Solute carrier family 17 member 8. (439 aa)
EFHC1EF-hand domain containing 1. (588 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (235 aa)
HOMER2Homer scaffold protein 2. (354 aa)
CIB3Calcium and integrin binding family member 3. (209 aa)
G3BP1G3BP stress granule assembly factor 1. (481 aa)
LOC102363355ETS domain-containing protein. (380 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (743 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (599 aa)
H3BFU5_LATCHAIP3 domain-containing protein. (914 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
KCND3BTB domain-containing protein; Belongs to the potassium channel family. (320 aa)
NRGNNeurogranin. (75 aa)
H3BGI5_LATCHUncharacterized protein; Belongs to the potassium channel family. (271 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (835 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2066 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (704 aa)
TMPRSS5Transmembrane serine protease 5; Belongs to the peptidase S1 family. (399 aa)
DIXDC1DIX domain containing 1. (695 aa)
SLC4A8Anion exchange protein. (1081 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (601 aa)
RIN3Ras and Rab interactor 3. (951 aa)
DIP2BDisco interacting protein 2 homolog B. (1576 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (436 aa)
MBPMyelin basic protein. (133 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
LOC102355574Potassium voltage-gated channel, Shaw-related subfamily, member 3b; Belongs to the potassium channel family. (609 aa)
MCRS1Microspherule protein 1. (479 aa)
DENND1ADENN domain containing 1A. (1001 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (874 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B. (907 aa)
APODApolipoprotein D; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
APOBApolipoprotein B. (4644 aa)
LOC102345237Uncharacterized protein. (390 aa)
LOC102347127ADF-H domain-containing protein. (892 aa)
PDE1APhosphodiesterase. (543 aa)
LOC102350310GBP domain-containing protein. (339 aa)
TNFRSF1BTNF receptor superfamily member 1B. (465 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (463 aa)
LOC102352322Aamy domain-containing protein. (520 aa)
M3XLM0_LATCHSERPIN domain-containing protein; Belongs to the serpin family. (407 aa)
KCNJ14Potassium voltage-gated channel subfamily J member 14. (440 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (12%) [HD]