STRINGSTRING
H2ZS97_LATCH H2ZS97_LATCH H2ZSA7_LATCH H2ZSA7_LATCH TFAP4 TFAP4 H2ZSP9_LATCH H2ZSP9_LATCH BIRC2 BIRC2 FABP1 FABP1 UACA UACA AIFM1 AIFM1 LOC102353315 LOC102353315 CAAP1 CAAP1 CASP8AP2 CASP8AP2 H2ZX20_LATCH H2ZX20_LATCH CASP10 CASP10 FNIP1 FNIP1 H2ZYB6_LATCH H2ZYB6_LATCH CASP2 CASP2 TNFAIP8 TNFAIP8 TNFSF15 TNFSF15 LOC102350164 LOC102350164 LOC102348725 LOC102348725 F3 F3 H3A2R2_LATCH H3A2R2_LATCH MALT1 MALT1 H3A4J0_LATCH H3A4J0_LATCH PAK2 PAK2 H3A526_LATCH H3A526_LATCH LOC102345518 LOC102345518 LOC102361141 LOC102361141 NLE1 NLE1 H3A7T5_LATCH H3A7T5_LATCH LOC102363280 LOC102363280 CTSH CTSH FAS FAS LOC102351334 LOC102351334 GRAMD4 GRAMD4 PDCD2 PDCD2 RPS3 RPS3 BAX BAX SFRP2 SFRP2 DHCR24 DHCR24 LTA LTA H3AEK5_LATCH H3AEK5_LATCH GPER1 GPER1 H3AEV1_LATCH H3AEV1_LATCH ANKRD24 ANKRD24 SOX7 SOX7 SIRT1 SIRT1 PTGS2 PTGS2 ACVR1C ACVR1C BOK BOK LOC102349920 LOC102349920 H3AKZ9_LATCH H3AKZ9_LATCH H3ALU7_LATCH H3ALU7_LATCH ACER2 ACER2 BAD BAD H3APB7_LATCH H3APB7_LATCH H3APC7_LATCH H3APC7_LATCH H3AQ35_LATCH H3AQ35_LATCH USP47 USP47 SH3RF1 SH3RF1 LOC102359041 LOC102359041 SYK SYK LOC102346472 LOC102346472 HTRA2 HTRA2 INTS1 INTS1 H3AUI0_LATCH H3AUI0_LATCH H3AVE1_LATCH H3AVE1_LATCH IFT57 IFT57 PDCD5 PDCD5 NAIP NAIP NLRC4 NLRC4 MAP2K5 MAP2K5 PIH1D1 PIH1D1 APAF1 APAF1 MMP9 MMP9 LOC102359057 LOC102359057 H3B0U4_LATCH H3B0U4_LATCH CDKN2D CDKN2D ARL6IP5 ARL6IP5 H3B1U1_LATCH H3B1U1_LATCH GAS6 GAS6 PRDX3 PRDX3 H3B5B6_LATCH H3B5B6_LATCH RACK1 RACK1 LOC102359774 LOC102359774 FASLG FASLG LOC102353021 LOC102353021 BAK1 BAK1 XIAP XIAP TNFSF14 TNFSF14 MYC MYC CCN1 CCN1 LAPTM5 LAPTM5 BIRC5 BIRC5 LOC102367479 LOC102367479 CARD9 CARD9 HIP1R HIP1R PRDX5 PRDX5 DIABLO DIABLO THBS1 THBS1 CASP9 CASP9 LAMTOR5 LAMTOR5 P2RX1 P2RX1 RNF34 RNF34 RFFL RFFL CRYAB CRYAB HIP1 HIP1 NR4A1 NR4A1 ST18 ST18 DELE1 DELE1 MUL1 MUL1 EIF2AK3 EIF2AK3 M3XHJ5_LATCH M3XHJ5_LATCH LOC106706381 LOC106706381 TP63 TP63 HGF HGF CRADD CRADD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
H2ZSA7_LATCHNACHT domain-containing protein. (707 aa)
TFAP4Transcription factor AP-4. (350 aa)
H2ZSP9_LATCHUncharacterized protein. (997 aa)
BIRC2Baculoviral IAP repeat containing 2. (616 aa)
FABP1Fatty acid binding protein 1. (98 aa)
UACAUveal autoantigen with coiled-coil domains and ankyrin repeats. (1124 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (625 aa)
LOC102353315Uncharacterized protein. (381 aa)
CAAP1Caspase activity and apoptosis inhibitor 1. (295 aa)
CASP8AP2Caspase 8 associated protein 2. (1555 aa)
H2ZX20_LATCHUncharacterized protein. (1016 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)
FNIP1Folliculin interacting protein 1. (1156 aa)
H2ZYB6_LATCHUncharacterized protein. (324 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (433 aa)
TNFAIP8TNF alpha induced protein 8. (198 aa)
TNFSF15TNF superfamily member 15. (151 aa)
LOC102350164Uncharacterized protein. (364 aa)
LOC102348725Uncharacterized protein. (641 aa)
F3Coagulation factor III, tissue factor. (286 aa)
H3A2R2_LATCHUncharacterized protein; Belongs to the peptidase C14A family. (480 aa)
MALT1MALT1 paracaspase. (825 aa)
H3A4J0_LATCHNACHT domain-containing protein. (800 aa)
PAK2Non-specific serine/threonine protein kinase. (521 aa)
H3A526_LATCHUncharacterized protein; Belongs to the peptidase C14A family. (486 aa)
LOC102345518Death-associated protein. (104 aa)
LOC102361141TNF_2 domain-containing protein. (216 aa)
NLE1Notchless homolog 1. (488 aa)
H3A7T5_LATCHUncharacterized protein. (999 aa)
LOC102363280Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (329 aa)
FASUncharacterized protein. (330 aa)
LOC102351334Scinderin like a. (721 aa)
GRAMD4GRAM domain containing 4. (575 aa)
PDCD2Programmed cell death 2. (366 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (254 aa)
BAXUncharacterized protein. (223 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
DHCR2424-dehydrocholesterol reductase. (516 aa)
LTALymphotoxin alpha. (166 aa)
H3AEK5_LATCHAquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (268 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
ANKRD24Ankyrin repeat domain 24. (970 aa)
SOX7SRY-box transcription factor 7. (369 aa)
SIRT1Sirtuin 1. (729 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (620 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
BOKBCL2 family apoptosis regulator BOK. (111 aa)
LOC102349920Uncharacterized protein. (199 aa)
H3AKZ9_LATCHNACHT domain-containing protein. (657 aa)
H3ALU7_LATCHNACHT domain-containing protein. (877 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (226 aa)
BADUncharacterized protein. (175 aa)
H3APB7_LATCHMitochondrial E3 ubiquitin protein ligase 1a. (243 aa)
H3APC7_LATCHNACHT domain-containing protein. (686 aa)
H3AQ35_LATCHNACHT domain-containing protein. (880 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1381 aa)
SH3RF1SH3 domain containing ring finger 1. (745 aa)
LOC102359041Zgc:153993. (208 aa)
SYKTyrosine-protein kinase. (616 aa)
LOC102346472Uncharacterized protein. (168 aa)
HTRA2HtrA serine peptidase 2. (525 aa)
INTS1Integrator complex subunit 1. (2183 aa)
H3AUI0_LATCHNACHT domain-containing protein. (572 aa)
H3AVE1_LATCHNACHT domain-containing protein. (574 aa)
IFT57Intraflagellar transport 57. (428 aa)
PDCD5Programmed cell death 5. (128 aa)
NAIPNLR family apoptosis inhibitory protein. (1422 aa)
NLRC4NLR family CARD domain containing 4. (1032 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
PIH1D1Uncharacterized protein. (294 aa)
APAF1Apoptotic peptidase activating factor 1. (1202 aa)
MMP9Matrix metallopeptidase 9. (682 aa)
LOC102359057Uncharacterized protein. (103 aa)
H3B0U4_LATCHMALT paracaspase 2. (695 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (168 aa)
ARL6IP5PRA1 family protein. (196 aa)
H3B1U1_LATCHRING-type domain-containing protein. (527 aa)
GAS6Uncharacterized protein. (681 aa)
PRDX3Peroxiredoxin 3. (254 aa)
H3B5B6_LATCHNACHT domain-containing protein. (692 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
LOC102359774Uncharacterized protein. (218 aa)
FASLGFas ligand. (261 aa)
LOC102353021Uncharacterized protein. (644 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
XIAPX-linked inhibitor of apoptosis. (606 aa)
TNFSF14TNF_2 domain-containing protein. (238 aa)
MYCTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (412 aa)
CCN1Cellular communication network factor 1. (368 aa)
LAPTM5Lysosomal protein transmembrane 5. (268 aa)
BIRC5Baculoviral IAP repeat containing 5. (139 aa)
LOC102367479Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (992 aa)
CARD9Caspase recruitment domain family member 9. (567 aa)
HIP1RHuntingtin interacting protein 1 related. (1039 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (190 aa)
DIABLODiablo, IAP-binding mitochondrial protein b. (257 aa)
THBS1Thrombospondin 1. (1170 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (457 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (92 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (403 aa)
RNF34Ring finger protein 34. (384 aa)
RFFLRing finger and FYVE-like domain containing E3 ubiquitin protein ligase. (361 aa)
CRYABCrystallin alpha B; Belongs to the small heat shock protein (HSP20) family. (173 aa)
HIP1Huntingtin interacting protein 1. (1004 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (580 aa)
ST18ST18 C2H2C-type zinc finger transcription factor. (1170 aa)
DELE1Uncharacterized protein. (461 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (958 aa)
M3XHJ5_LATCHUncharacterized protein. (158 aa)
LOC106706381Uncharacterized protein. (224 aa)
TP63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (637 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (720 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (143 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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