(24 nodes) Positive regulation of JUN kinase activity network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (439 aa)
	LOC102358266	Dickkopf WNT signaling pathway inhibitor 1b. (261 aa)
	RPS3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (254 aa)
	H3AEV1_LATCH	TNF_2 domain-containing protein. (230 aa)
	DUSP19	Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (213 aa)
	MAP3K11	Mitogen-activated protein kinase kinase kinase 11. (831 aa)
	H3AMR9_LATCH	Uncharacterized protein. (285 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7. (580 aa)
	SYK	Tyrosine-protein kinase. (616 aa)
	ERN2	Endoplasmic reticulum to nucleus signaling 2. (974 aa)
	LOC102355766	Uncharacterized protein. (524 aa)
	LOC102359313	Uncharacterized protein. (334 aa)
	MAP2K7	Mitogen-activated protein kinase kinase 7. (439 aa)
	EDN1	Endothelin 1. (216 aa)
	ERN1	Endoplasmic reticulum to nucleus signaling 1. (956 aa)
	LOC102363206	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
	H2ZS97_LATCH	TNF_2 domain-containing protein. (143 aa)
	FZD8	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	LOC102358853	Uncharacterized protein. (577 aa)
	ROR2	Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (882 aa)
	FZD4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (530 aa)
	MAP3K4	Mitogen-activated protein kinase kinase kinase 4. (1425 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
	MAP3K12	Mitogen-activated protein kinase kinase kinase. (904 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP19	MAP2K7	ENSLACP00000008876	ENSLACP00000015207	Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase kinase 7.	0.649
FZD4	FZD8	ENSLACP00000001995	ENSLACP00000001454	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.414
FZD4	LOC102363206	ENSLACP00000001995	ENSLACP00000018675	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.410
FZD4	ROR2	ENSLACP00000001995	ENSLACP00000001497	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.409
FZD8	FZD4	ENSLACP00000001454	ENSLACP00000001995	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.414
FZD8	ROR2	ENSLACP00000001454	ENSLACP00000001497	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.493
LOC102363206	FZD4	ENSLACP00000018675	ENSLACP00000001995	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.410
LOC102363206	ROR2	ENSLACP00000018675	ENSLACP00000001497	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.493
MAP2K7	DUSP19	ENSLACP00000015207	ENSLACP00000008876	Mitogen-activated protein kinase kinase 7.	Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.649
MAP2K7	MAP3K11	ENSLACP00000015207	ENSLACP00000010903	Mitogen-activated protein kinase kinase 7.	Mitogen-activated protein kinase kinase kinase 11.	0.548
MAP2K7	MAP3K12	ENSLACP00000015207	ENSLACP00000003738	Mitogen-activated protein kinase kinase 7.	Mitogen-activated protein kinase kinase kinase.	0.450
MAP2K7	MAP3K7	ENSLACP00000015207	ENSLACP00000011169	Mitogen-activated protein kinase kinase 7.	Mitogen-activated protein kinase kinase kinase 7.	0.802
MAP2K7	SYK	ENSLACP00000015207	ENSLACP00000012982	Mitogen-activated protein kinase kinase 7.	Tyrosine-protein kinase.	0.437
MAP2K7	TRAF6	ENSLACP00000015207	ENSLACP00000003556	Mitogen-activated protein kinase kinase 7.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.521
MAP3K11	MAP2K7	ENSLACP00000010903	ENSLACP00000015207	Mitogen-activated protein kinase kinase kinase 11.	Mitogen-activated protein kinase kinase 7.	0.548
MAP3K11	TRAF6	ENSLACP00000010903	ENSLACP00000003556	Mitogen-activated protein kinase kinase kinase 11.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.683
MAP3K12	MAP2K7	ENSLACP00000003738	ENSLACP00000015207	Mitogen-activated protein kinase kinase kinase.	Mitogen-activated protein kinase kinase 7.	0.450
MAP3K7	MAP2K7	ENSLACP00000011169	ENSLACP00000015207	Mitogen-activated protein kinase kinase kinase 7.	Mitogen-activated protein kinase kinase 7.	0.802
MAP3K7	TRAF6	ENSLACP00000011169	ENSLACP00000003556	Mitogen-activated protein kinase kinase kinase 7.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
ROR2	FZD4	ENSLACP00000001497	ENSLACP00000001995	Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.409