STRINGSTRING
LGR5 LGR5 LRRC1 LRRC1 GAS1 GAS1 WDR19 WDR19 PDZD7 PDZD7 JAG1 JAG1 KCNK2 KCNK2 IFT88 IFT88 CCM2 CCM2 FREM3 FREM3 DLX5 DLX5 DDR1 DDR1 SLITRK6 SLITRK6 H2ZYB6_LATCH H2ZYB6_LATCH DLX6 DLX6 FREM2-2 FREM2-2 H3A0S5_LATCH H3A0S5_LATCH MYO3A MYO3A GATA3 GATA3 OTOP1 OTOP1 GABRA5 GABRA5 ATG4B ATG4B NKX3-2 NKX3-2 GLI3 GLI3 H3A478_LATCH H3A478_LATCH MSX1 MSX1 EYA4 EYA4 RDH10 RDH10 H3A4P0_LATCH H3A4P0_LATCH H3A4S8_LATCH H3A4S8_LATCH PJVK PJVK SLC26A5 SLC26A5 PHOX2B PHOX2B NIPBL NIPBL GSC GSC SLC4A7 SLC4A7 EDNRA EDNRA OSR2 OSR2 GBX2 GBX2 MYO3B MYO3B NAGLU NAGLU OSR1 OSR1 LOC102360373 LOC102360373 LOC102362960 LOC102362960 MAPKAPK2 MAPKAPK2 TBX3 TBX3 SEC24B SEC24B FGF8 FGF8 LRIG1 LRIG1 CECR2 CECR2 GSDME GSDME FREM2 FREM2 GRXCR1 GRXCR1 ADAM10 ADAM10 LOC102363509 LOC102363509 DLL3 DLL3 C1QB C1QB LOC102351081 LOC102351081 H3AHJ4_LATCH H3AHJ4_LATCH MYO6 MYO6 DLL1 DLL1 H3AIG1_LATCH H3AIG1_LATCH PTPRQ PTPRQ LOC102366915 LOC102366915 CLDN7 CLDN7 S1PR2 S1PR2 KCNQ1 KCNQ1 ROR1 ROR1 ADGRV1 ADGRV1 H3ALU1_LATCH H3ALU1_LATCH LOC102357614 LOC102357614 NBL1 NBL1 USH1G USH1G GRXCR2 GRXCR2 HESX1 HESX1 MCM2 MCM2 PLS1 PLS1 LOC102350991 LOC102350991 FZD3 FZD3 H3AU65_LATCH H3AU65_LATCH TIFAB TIFAB BLOC1S5 BLOC1S5 SOBP SOBP JAG2 JAG2 FOXG1 FOXG1 TMIE TMIE LOC102362405 LOC102362405 LOC102359345 LOC102359345 ATG5 ATG5 ZEB1 ZEB1 TPRN TPRN HPN HPN PTK7 PTK7 SIX2 SIX2 CTHRC1 CTHRC1 CEBPD CEBPD TBX2 TBX2 EYA1 EYA1 TTC39C TTC39C LOC102365660 LOC102365660 LOC102366172 LOC102366172 USH1C USH1C LRIG3 LRIG3 C1QTNF5 C1QTNF5 TSHR TSHR EDN1 EDN1 FGF2 FGF2 H3BBK0_LATCH H3BBK0_LATCH OTX1 OTX1 HOXA13 HOXA13 SLC17A8 SLC17A8 ALDH1A3 ALDH1A3 LOC102347946 LOC102347946 IFT20 IFT20 SIX4 SIX4 SIX1 SIX1 MKS1 MKS1 WNT1 WNT1 TRIP11 TRIP11 M3XHJ5_LATCH M3XHJ5_LATCH BMPER BMPER SLC44A4 SLC44A4 TTC8 TTC8 WDPCP WDPCP RPGRIP1L RPGRIP1L CXCL14 CXCL14 STRA6 STRA6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (625 aa)
LRRC1Uncharacterized protein. (155 aa)
GAS1Growth arrest specific 1. (259 aa)
WDR19WD repeat domain 19. (895 aa)
PDZD7PDZ domain containing 7. (505 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1220 aa)
KCNK2Potassium two pore domain channel subfamily K member 2. (280 aa)
IFT88Intraflagellar transport 88. (833 aa)
CCM2CCM2 scaffold protein. (447 aa)
FREM3FRAS1 related extracellular matrix 3. (3131 aa)
DLX5Distal-less homeobox 5. (290 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (964 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
H2ZYB6_LATCHUncharacterized protein. (324 aa)
DLX6Distal-less homeobox 6. (266 aa)
FREM2-2Uncharacterized protein. (1618 aa)
H3A0S5_LATCHUncharacterized protein. (547 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (600 aa)
GATA3GATA binding protein 3. (447 aa)
OTOP1Otopetrin 1. (584 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (454 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (396 aa)
NKX3-2NK3 homeobox 2. (282 aa)
GLI3GLI family zinc finger 3. (1456 aa)
H3A478_LATCHPDZ domain-containing protein. (297 aa)
MSX1Msh homeobox 1. (256 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (620 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (348 aa)
H3A4P0_LATCHIg-like domain-containing protein. (174 aa)
H3A4S8_LATCHUncharacterized protein. (2030 aa)
PJVKPejvakin. (355 aa)
SLC26A5Solute carrier family 26 member 5. (755 aa)
PHOX2BPaired like homeobox 2B. (287 aa)
NIPBLNipped-B protein. (2707 aa)
GSCGoosecoid homeobox. (243 aa)
SLC4A7Anion exchange protein. (1213 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
OSR2Odd-skipped related transciption factor 2. (314 aa)
GBX2Gastrulation brain homeobox 2. (344 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (805 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (614 aa)
OSR1Odd-skipped related transcription factor 1. (259 aa)
LOC102360373Fork-head domain-containing protein. (374 aa)
LOC102362960Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (256 aa)
MAPKAPK2MAPK activated protein kinase 2. (332 aa)
TBX3T-box transcription factor 3. (713 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1197 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1097 aa)
CECR2CECR2 histone acetyl-lysine reader. (1363 aa)
GSDMEUncharacterized protein. (491 aa)
FREM2Uncharacterized protein. (1163 aa)
GRXCR1Glutaredoxin and cysteine rich domain containing 1. (213 aa)
ADAM10ADAM metallopeptidase domain 10b. (679 aa)
LOC102363509Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (248 aa)
DLL3Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa)
C1QBComplement C1q B chain. (333 aa)
LOC102351081Bone morphogenetic protein 16. (396 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1230 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
H3AIG1_LATCHUncharacterized protein. (317 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (1795 aa)
LOC102366915Uncharacterized protein. (146 aa)
CLDN7Claudin 7b. (145 aa)
S1PR2Sphingosine-1-phosphate receptor 2. (352 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1. (769 aa)
ADGRV1Adhesion G protein-coupled receptor V1. (5847 aa)
H3ALU1_LATCHUncharacterized protein. (1358 aa)
LOC102357614Fork-head domain-containing protein. (345 aa)
NBL1NBL1, DAN family BMP antagonist. (184 aa)
USH1GUSH1 protein network component sans. (471 aa)
GRXCR2Glutaredoxin and cysteine rich domain containing 2. (260 aa)
HESX1HESX homeobox 1. (185 aa)
MCM2DNA helicase; Belongs to the MCM family. (888 aa)
PLS1Plastin 1. (621 aa)
LOC102350991Uncharacterized protein. (1471 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (604 aa)
H3AU65_LATCHPhospholipase A(2). (398 aa)
TIFABTIFA inhibitor. (149 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (154 aa)
SOBPSine oculis binding protein homolog. (634 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1106 aa)
FOXG1Forkhead box G1. (409 aa)
TMIETransmembrane inner ear. (130 aa)
LOC102362405Homeobox domain-containing protein. (954 aa)
LOC102359345Transmembrane O-methyltransferase. (268 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1076 aa)
TPRNTaperin. (771 aa)
HPNHepsin; Belongs to the peptidase S1 family. (415 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1067 aa)
SIX2SIX homeobox 2. (289 aa)
CTHRC1Collagen triple helix repeat containing 1. (151 aa)
CEBPDCCAAT/enhancer-binding protein. (288 aa)
TBX2T-box transcription factor 2. (689 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (646 aa)
TTC39CTetratricopeptide repeat domain 39C. (448 aa)
LOC102365660Uncharacterized protein. (187 aa)
LOC102366172Uncharacterized protein. (183 aa)
USH1CUSH1 protein network component harmonin. (830 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1035 aa)
C1QTNF5C1q and TNF related 5. (248 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (689 aa)
EDN1Endothelin 1. (216 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
H3BBK0_LATCHUncharacterized protein. (783 aa)
OTX1Orthodenticle homeobox 1. (339 aa)
HOXA13Homeobox A13b. (295 aa)
SLC17A8Solute carrier family 17 member 8. (439 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (507 aa)
LOC102347946Transferrin-like domain-containing protein. (362 aa)
IFT20Intraflagellar transport 20. (132 aa)
SIX4SIX homeobox 4. (742 aa)
SIX1SIX homeobox 1. (283 aa)
MKS1MKS transition zone complex subunit 1. (561 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
TRIP11Thyroid hormone receptor interactor 11. (1997 aa)
M3XHJ5_LATCHUncharacterized protein. (158 aa)
BMPERBMP binding endothelial regulator. (682 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (470 aa)
TTC8Tetratricopeptide repeat domain 8. (534 aa)
WDPCPWD repeat containing planar cell polarity effector. (727 aa)
RPGRIP1LRPGRIP1 like. (1318 aa)
CXCL14C-X-C motif chemokine ligand 14. (98 aa)
STRA6Stimulated by retinoic acid 6. (664 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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