STRINGSTRING
ME2 ME2 GOT1L1 GOT1L1 KYNU KYNU MRPS36 MRPS36 ALDH4A1 ALDH4A1 SHMT2 SHMT2 GLS2 GLS2 DLST DLST ACOT8 ACOT8 MDH2 MDH2 LOC102348032 LOC102348032 IDH2 IDH2 PCK1 PCK1 FPGS FPGS LOC102353714 LOC102353714 H3BAN4_LATCH H3BAN4_LATCH MDH1 MDH1 MTHFD1 MTHFD1 GLS GLS NAGS NAGS OAT OAT IDH1 IDH1 ALDH1L1 ALDH1L1 GOT1 GOT1 GAD1 GAD1 FTCD FTCD ALDH18A1 ALDH18A1 GCLM GCLM H3AQW3_LATCH H3AQW3_LATCH OGDHL OGDHL DGLUCY DGLUCY GAD2 GAD2 SHMT1 SHMT1 DDO DDO ME3 ME3 LOC102354904 LOC102354904 KMO KMO H3AH67_LATCH H3AH67_LATCH LOC102353169 LOC102353169 MTRR MTRR FH FH SDHA SDHA GLUD1 GLUD1 MTHFD1L MTHFD1L MDH1B MDH1B GRHPR GRHPR NIT2 NIT2 LOC102352834 LOC102352834 LOC102365118 LOC102365118 ALDH5A1 ALDH5A1 ALDH1L2 ALDH1L2 D2HGDH D2HGDH ACLY ACLY AADAT AADAT HAL HAL PRODH2 PRODH2 LOC102358828 LOC102358828 ACSF3 ACSF3 AMDHD1 AMDHD1 HAAO HAAO GOT2 GOT2 GCLC GCLC SDHAF3 SDHAF3 TAT TAT QPRT QPRT LOC102351739 LOC102351739 ADHFE1 ADHFE1 H2ZRQ5_LATCH H2ZRQ5_LATCH LOC102364781 LOC102364781
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ME2Malic enzyme. (543 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (405 aa)
KYNUKynureninase. (278 aa)
MRPS36Mitochondrial ribosomal protein S36. (100 aa)
ALDH4A1Aldehyde dehydrogenase 4 family member A1; Belongs to the aldehyde dehydrogenase family. (1427 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (542 aa)
GLS2Glutaminase 2. (601 aa)
DLSTDihydrolipoamide S-succinyltransferase. (458 aa)
ACOT8Acyl-CoA thioesterase 8. (332 aa)
MDH2Malate dehydrogenase. (337 aa)
LOC102348032Zgc:153901. (333 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (595 aa)
LOC102353714Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (628 aa)
H3BAN4_LATCHOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (773 aa)
MDH1Malate dehydrogenase. (335 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (930 aa)
GLSGlutaminase. (577 aa)
NAGSN-acetylglutamate synthase. (508 aa)
OATOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
ALDH1L110-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (900 aa)
GOT1Aspartate aminotransferase. (399 aa)
GAD1Glutamate decarboxylase 1. (590 aa)
FTCDFormimidoyltransferase cyclodeaminase. (547 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (796 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
H3AQW3_LATCHZgc:113208. (209 aa)
OGDHLOxoglutarate dehydrogenase like. (1017 aa)
DGLUCYD-glutamate cyclase. (623 aa)
GAD2Glutamate decarboxylase 2. (476 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (474 aa)
DDOD-aspartate oxidase. (338 aa)
ME3Malic enzyme. (617 aa)
LOC102354904Uncharacterized protein. (648 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (474 aa)
H3AH67_LATCHGlyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (368 aa)
LOC102353169Uncharacterized protein. (245 aa)
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (720 aa)
FHFumarate hydratase. (491 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (670 aa)
GLUD1Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (541 aa)
MTHFD1LUncharacterized protein. (90 aa)
MDH1BMalate dehydrogenase 1B. (470 aa)
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
NIT2Nitrilase family member 2. (283 aa)
LOC102352834Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (424 aa)
LOC102365118Uncharacterized protein. (196 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (511 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (924 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase. (564 aa)
ACLYATP citrate lyase. (978 aa)
AADATAminoadipate aminotransferase. (425 aa)
HALHistidine ammonia-lyase. (539 aa)
PRODH2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (433 aa)
LOC102358828Zgc:136493; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (350 aa)
ACSF3Acyl-CoA synthetase family member 3. (345 aa)
AMDHD1Amidohydrolase domain containing 1. (161 aa)
HAAOUncharacterized protein. (252 aa)
GOT2Aspartate aminotransferase. (392 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (655 aa)
SDHAF3Succinate dehydrogenase complex assembly factor 3. (127 aa)
TATTyrosine aminotransferase. (183 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (324 aa)
LOC1023517392-Hacid_dh_C domain-containing protein. (197 aa)
ADHFE1Alcohol dehydrogenase iron containing 1. (249 aa)
H2ZRQ5_LATCH2-Hacid_dh_C domain-containing protein. (80 aa)
LOC102364781Histidine ammonia-lyase; Belongs to the PAL/histidase family. (627 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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