(17 nodes) Mitochondria-associated endoplasmic reticulum membrane network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAB38	RAB38b, member of RAS oncogene family. (112 aa)
	TMX2	Thioredoxin-related transmembrane protein 2a. (307 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (713 aa)
	SERAC1	Serine active site containing 1. (657 aa)
	STX17	Syntaxin 17. (308 aa)
	BCL2L10	BCL2 like 10. (178 aa)
	LOC102360588	Uncharacterized protein. (214 aa)
	MBOAT7	Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (468 aa)
	ZFYVE1	Zinc finger FYVE-type containing 1. (782 aa)
	CLCC1	Uncharacterized protein. (420 aa)
	RAB38-2	RAB38b, member of RAS oncogene family. (79 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	TMEM41B	Transmembrane protein 41B. (285 aa)
	LOC102357932	Si:ch211-11n16.2. (535 aa)
	ATG14	Autophagy related 14. (499 aa)
	LOC102367143	Uncharacterized protein. (214 aa)
	RAB32	Uncharacterized protein. (174 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG14	ATG5	ENSLACP00000021664	ENSLACP00000015035	Autophagy related 14.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.933
ATG14	STX17	ENSLACP00000021664	ENSLACP00000006722	Autophagy related 14.	Syntaxin 17.	0.792
ATG14	ZFYVE1	ENSLACP00000021664	ENSLACP00000014063	Autophagy related 14.	Zinc finger FYVE-type containing 1.	0.499
ATG5	ATG14	ENSLACP00000015035	ENSLACP00000021664	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy related 14.	0.933
ATG5	STX17	ENSLACP00000015035	ENSLACP00000006722	Autophagy protein 5; Involved in autophagic vesicle formation.	Syntaxin 17.	0.704
ATG5	ZFYVE1	ENSLACP00000015035	ENSLACP00000014063	Autophagy protein 5; Involved in autophagic vesicle formation.	Zinc finger FYVE-type containing 1.	0.437
STX17	ATG14	ENSLACP00000006722	ENSLACP00000021664	Syntaxin 17.	Autophagy related 14.	0.792
STX17	ATG5	ENSLACP00000006722	ENSLACP00000015035	Syntaxin 17.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.704
ZFYVE1	ATG14	ENSLACP00000014063	ENSLACP00000021664	Zinc finger FYVE-type containing 1.	Autophagy related 14.	0.499
ZFYVE1	ATG5	ENSLACP00000014063	ENSLACP00000015035	Zinc finger FYVE-type containing 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.437