(33 nodes) Establishment or maintenance of epithelial cell apical/basal polarity network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	LRRC1	Uncharacterized protein. (155 aa)
	NT5DC3	5'-nucleotidase domain containing 3. (472 aa)
	PARD3B	Uncharacterized protein. (1094 aa)
	LOC102349972	Uncharacterized protein. (246 aa)
	DLG5	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1821 aa)
	ILK	Integrin linked kinase. (417 aa)
	CRB1	Crumbs cell polarity complex component 1. (1366 aa)
	MYO9A	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2366 aa)
	H3ALU1_LATCH	Uncharacterized protein. (1358 aa)
	MPP5	Membrane palmitoylated protein 5; Belongs to the MAGUK family. (678 aa)
	PDCD6IP	Programmed cell death 6 interacting protein. (732 aa)
	SYNJ2BP	PDZ domain-containing protein. (107 aa)
	DLG2	Guanylate kinase-like domain-containing protein. (215 aa)
	LIN7A	Lin-7 homolog A, crumbs cell polarity complex component. (168 aa)
	LIN7C	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (200 aa)
	LOC102350904	5'-nucleotidase domain containing 2. (600 aa)
	FAT1	FAT atypical cadherin 1. (3389 aa)
	H3AYY9_LATCH	Uncharacterized protein. (127 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (828 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1067 aa)
	PARD6A	Par-6 family cell polarity regulator alpha. (307 aa)
	PDZD11	PDZ domain containing 11. (142 aa)
	PARD3	Par-3 family cell polarity regulator. (1214 aa)
	MSN	Moesin. (583 aa)
	CDC42	Cell division cycle 42. (156 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (928 aa)
	CDX2	Caudal type homeobox 2. (258 aa)
	LIN7B	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (208 aa)
	IFT20	Intraflagellar transport 20. (132 aa)
	NT5DC2	5'-nucleotidase domain containing 2. (552 aa)
	CRB2	Uncharacterized protein. (1473 aa)
	TTC8	Tetratricopeptide repeat domain 8. (534 aa)
	DLG3	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (901 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	DLG5	ENSLACP00000018010	ENSLACP00000005485	Cell division cycle 42.	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	0.527
CDC42	H3ALU1_LATCH	ENSLACP00000018010	ENSLACP00000010612	Cell division cycle 42.	Uncharacterized protein.	0.517
CDC42	H3AYY9_LATCH	ENSLACP00000018010	ENSLACP00000014860	Cell division cycle 42.	Uncharacterized protein.	0.419
CDC42	ILK	ENSLACP00000018010	ENSLACP00000006792	Cell division cycle 42.	Integrin linked kinase.	0.520
CDC42	LRRC1	ENSLACP00000018010	ENSLACP00000000728	Cell division cycle 42.	Uncharacterized protein.	0.517
CDC42	MPP5	ENSLACP00000018010	ENSLACP00000011136	Cell division cycle 42.	Membrane palmitoylated protein 5; Belongs to the MAGUK family.	0.633
CDC42	MSN	ENSLACP00000018010	ENSLACP00000017220	Cell division cycle 42.	Moesin.	0.564
CDC42	MYO9A	ENSLACP00000018010	ENSLACP00000010473	Cell division cycle 42.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.773
CDC42	PARD3	ENSLACP00000018010	ENSLACP00000017073	Cell division cycle 42.	Par-3 family cell polarity regulator.	0.732
CDC42	PARD3B	ENSLACP00000018010	ENSLACP00000004232	Cell division cycle 42.	Uncharacterized protein.	0.419
CDC42	PARD6A	ENSLACP00000018010	ENSLACP00000016214	Cell division cycle 42.	Par-6 family cell polarity regulator alpha.	0.912
CRB1	MPP5	ENSLACP00000006909	ENSLACP00000011136	Crumbs cell polarity complex component 1.	Membrane palmitoylated protein 5; Belongs to the MAGUK family.	0.899
CRB2	MPP5	ENSLACP00000021515	ENSLACP00000011136	Uncharacterized protein.	Membrane palmitoylated protein 5; Belongs to the MAGUK family.	0.899
DLG1	LIN7A	ENSLACP00000018954	ENSLACP00000013268	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Lin-7 homolog A, crumbs cell polarity complex component.	0.410
DLG1	LIN7B	ENSLACP00000018954	ENSLACP00000020422	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.410
DLG1	LIN7C	ENSLACP00000018954	ENSLACP00000013471	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.410
DLG1	MYO9A	ENSLACP00000018954	ENSLACP00000010473	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.402
DLG1	PARD6A	ENSLACP00000018954	ENSLACP00000016214	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Par-6 family cell polarity regulator alpha.	0.400
DLG2	DLG3	ENSLACP00000013231	ENSLACP00000022891	Guanylate kinase-like domain-containing protein.	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.	0.805
DLG2	LIN7A	ENSLACP00000013231	ENSLACP00000013268	Guanylate kinase-like domain-containing protein.	Lin-7 homolog A, crumbs cell polarity complex component.	0.410