(32 nodes) Photoreceptor cell maintenance network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RP1	RP1 axonemal microtubule associated. (1901 aa)
	LCA5	Lebercilin LCA5. (743 aa)
	DRAM2	DNA damage regulated autophagy modulator 2. (142 aa)
	NPHP4	Nephrocystin 4. (1207 aa)
	CRB2	Uncharacterized protein. (1473 aa)
	NXNL1	Nucleoredoxin like 1. (221 aa)
	LOC102347432	Rhodopsin. (355 aa)
	USH1C	USH1 protein network component harmonin. (830 aa)
	CROCC	Uncharacterized protein. (1191 aa)
	BBS2	Bardet-Biedl syndrome 2 protein homolog. (724 aa)
	CDHR1	Cadherin related family member 1. (688 aa)
	RHO	Rhodopsin. (355 aa)
	NXNL2	Nucleoredoxin like 2. (157 aa)
	ERCC6	ERCC excision repair 6, chromatin remodeling factor. (1387 aa)
	LOC102350991	Uncharacterized protein. (1471 aa)
	H3ARD8_LATCH	Uncharacterized protein. (2003 aa)
	USP45	Ubiquitinyl hydrolase 1. (823 aa)
	USH1G	USH1 protein network component sans. (471 aa)
	ADGRV1	Adhesion G protein-coupled receptor V1. (5847 aa)
	IQCB1	IQ motif containing B1. (601 aa)
	RP1L1	Uncharacterized protein. (1547 aa)
	CRB1	Crumbs cell polarity complex component 1. (1366 aa)
	SPATA7	Spermatogenesis associated 7. (398 aa)
	MKKS	McKusick-Kaufman syndrome. (575 aa)
	BSG	Basigin (Ok blood group). (368 aa)
	H3A6Z7_LATCH	Bardet-Biedl syndrome 1. (596 aa)
	H3A4S8_LATCH	Uncharacterized protein. (2030 aa)
	CLN8	CLN8 transmembrane ER and ERGIC protein. (294 aa)
	BBS4	Bardet-Biedl syndrome 4. (537 aa)
	BBS10	Bardet-Biedl syndrome 10. (714 aa)
	BBS12	Bardet-Biedl syndrome 12. (709 aa)
	H2ZRN8_LATCH	Uncharacterized protein. (160 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRV1	H3A4S8_LATCH	ENSLACP00000010057	ENSLACP00000004649	Adhesion G protein-coupled receptor V1.	Uncharacterized protein.	0.535
ADGRV1	LOC102350991	ENSLACP00000010057	ENSLACP00000012767	Adhesion G protein-coupled receptor V1.	Uncharacterized protein.	0.755
ADGRV1	USH1C	ENSLACP00000010057	ENSLACP00000018193	Adhesion G protein-coupled receptor V1.	USH1 protein network component harmonin.	0.868
ADGRV1	USH1G	ENSLACP00000010057	ENSLACP00000012126	Adhesion G protein-coupled receptor V1.	USH1 protein network component sans.	0.690
BBS10	BBS12	ENSLACP00000001885	ENSLACP00000001386	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 12.	0.875
BBS10	BBS2	ENSLACP00000001885	ENSLACP00000017026	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 2 protein homolog.	0.727
BBS10	BBS4	ENSLACP00000001885	ENSLACP00000002102	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 4.	0.651
BBS10	H3A6Z7_LATCH	ENSLACP00000001885	ENSLACP00000005418	Bardet-Biedl syndrome 10.	Bardet-Biedl syndrome 1.	0.708
BBS10	MKKS	ENSLACP00000001885	ENSLACP00000006659	Bardet-Biedl syndrome 10.	McKusick-Kaufman syndrome.	0.697
BBS12	BBS10	ENSLACP00000001386	ENSLACP00000001885	Bardet-Biedl syndrome 12.	Bardet-Biedl syndrome 10.	0.875
BBS12	BBS2	ENSLACP00000001386	ENSLACP00000017026	Bardet-Biedl syndrome 12.	Bardet-Biedl syndrome 2 protein homolog.	0.717
BBS12	BBS4	ENSLACP00000001386	ENSLACP00000002102	Bardet-Biedl syndrome 12.	Bardet-Biedl syndrome 4.	0.633
BBS12	H3A6Z7_LATCH	ENSLACP00000001386	ENSLACP00000005418	Bardet-Biedl syndrome 12.	Bardet-Biedl syndrome 1.	0.648
BBS12	IQCB1	ENSLACP00000001386	ENSLACP00000009378	Bardet-Biedl syndrome 12.	IQ motif containing B1.	0.426
BBS12	MKKS	ENSLACP00000001386	ENSLACP00000006659	Bardet-Biedl syndrome 12.	McKusick-Kaufman syndrome.	0.811
BBS2	BBS10	ENSLACP00000017026	ENSLACP00000001885	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 10.	0.727
BBS2	BBS12	ENSLACP00000017026	ENSLACP00000001386	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 12.	0.717
BBS2	BBS4	ENSLACP00000017026	ENSLACP00000002102	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 4.	0.998
BBS2	H3A6Z7_LATCH	ENSLACP00000017026	ENSLACP00000005418	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 1.	0.998
BBS2	MKKS	ENSLACP00000017026	ENSLACP00000006659	Bardet-Biedl syndrome 2 protein homolog.	McKusick-Kaufman syndrome.	0.427