STRINGSTRING
H3AM65_LATCH H3AM65_LATCH MED1 MED1 STAT3 STAT3 INPP5D INPP5D FAM210B FAM210B ACVR1B ACVR1B LOC102354416 LOC102354416 TAL1 TAL1 SMAP1 SMAP1 H2ZX25_LATCH H2ZX25_LATCH BRD1 BRD1 ABCB10 ABCB10 INHBA INHBA GATA1 GATA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H3AM65_LATCHMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1144 aa)
FAM210BFamily with sequence similarity 210 member B. (163 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (489 aa)
LOC102354416Uncharacterized protein. (160 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (327 aa)
SMAP1Small ArfGAP 1. (474 aa)
H2ZX25_LATCHANK_REP_REGION domain-containing protein. (269 aa)
BRD1Bromodomain containing 1. (1190 aa)
ABCB10ATP binding cassette subfamily B member 10. (723 aa)
INHBAInhibin subunit beta A. (390 aa)
GATA1GATA binding protein 1b. (432 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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