STRINGSTRING
LOC102348760 LOC102348760 JAG1 JAG1 BMPR1B BMPR1B BMPR1A BMPR1A CEBPB CEBPB H2ZYB6_LATCH H2ZYB6_LATCH ACVR2A ACVR2A LOC102350164 LOC102350164 YAP1 YAP1 FAM20C FAM20C SEMA4D SEMA4D PTCH1 PTCH1 GLI3 GLI3 WWTR1-2 WWTR1-2 ATF4 ATF4 HAND2 HAND2 TNFAIP6 TNFAIP6 NBR1 NBR1 SMAD6 SMAD6 ILK ILK RORB RORB GREM1 GREM1 CTNNBIP1 CTNNBIP1 SFRP2 SFRP2 TMEM64 TMEM64 BAMBI BAMBI H2ZS97_LATCH H2ZS97_LATCH IGFBP5 IGFBP5 H3AEV1_LATCH H3AEV1_LATCH SMAD5 SMAD5 CHRD CHRD AREG AREG LOC102351081 LOC102351081 IL6 IL6 TNN TNN TWSG1 TWSG1 IL6ST IL6ST ID3 ID3 LOC102366200 LOC102366200 FBXO5 FBXO5 ACVR1 ACVR1 RANBP3L RANBP3L BMP6 BMP6 CITED1 CITED1 SMAD1 SMAD1 ACVR2B ACVR2B TWIST2 TWIST2 DDR2 DDR2 H3AXW7_LATCH H3AXW7_LATCH TWIST1 TWIST1 SKI SKI CTHRC1 CTHRC1 FNDC3B FNDC3B LOC102360711 LOC102360711 BMP2 BMP2 SUCO SUCO WWTR1 WWTR1 DDX5 DDX5 CEBPD CEBPD BMPR2 BMPR2 CTNNB1 CTNNB1 JUND JUND NOCT NOCT OSTN OSTN CCN1 CCN1 RIOX1 RIOX1 CRIM1 CRIM1 H3BEX6_LATCH H3BEX6_LATCH FGF23 FGF23 LRP5 LRP5 ZHX3 ZHX3 GLI1 GLI1 BMP4 BMP4 PDLIM7 PDLIM7 VEGFC VEGFC TP63 TP63 WDR63 WDR63 H2ZTF7_LATCH H2ZTF7_LATCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102348760Uncharacterized protein. (782 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1220 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
CEBPBCCAAT/enhancer-binding protein. (291 aa)
H2ZYB6_LATCHUncharacterized protein. (324 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
LOC102350164Uncharacterized protein. (364 aa)
YAP1Yes associated protein 1. (324 aa)
FAM20CFam20C domain-containing protein. (305 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
PTCH1Patched 1. (1287 aa)
GLI3GLI family zinc finger 3. (1456 aa)
WWTR1-2WW domain-containing protein. (159 aa)
ATF4Activating transcription factor 4. (374 aa)
HAND2Heart and neural crest derivatives expressed 2. (210 aa)
TNFAIP6TNF alpha induced protein 6. (279 aa)
NBR1NBR1 autophagy cargo receptor. (1005 aa)
SMAD6Mothers against decapentaplegic homolog. (485 aa)
ILKIntegrin linked kinase. (417 aa)
RORBRAR related orphan receptor B. (463 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (189 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
TMEM64Transmembrane protein 64. (350 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
IGFBP5Insulin like growth factor binding protein 5. (279 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
SMAD5Mothers against decapentaplegic homolog. (467 aa)
CHRDChordin; Belongs to the chordin family. (948 aa)
AREGAmphiregulin. (235 aa)
LOC102351081Bone morphogenetic protein 16. (396 aa)
IL6Uncharacterized protein. (149 aa)
TNNTenascin N. (831 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (220 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (121 aa)
LOC102366200Uncharacterized protein; Belongs to the semaphorin family. (627 aa)
FBXO5F-box protein 5. (313 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
RANBP3LRAN binding protein 3 like. (414 aa)
BMP6Bone morphogenetic protein 6. (428 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (165 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
TWIST2Twist family bHLH transcription factor 2. (161 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (838 aa)
H3AXW7_LATCHEGF-like domain-containing protein. (204 aa)
TWIST1Twist family bHLH transcription factor 1b. (169 aa)
SKISKI proto-oncogene. (702 aa)
CTHRC1Collagen triple helix repeat containing 1. (151 aa)
FNDC3BFibronectin type III domain containing 3B. (944 aa)
LOC102360711PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (299 aa)
BMP2Bone morphogenetic protein 2. (402 aa)
SUCOSUN domain containing ossification factor. (1247 aa)
WWTR1WW domain containing transcription regulator 1. (264 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (512 aa)
CEBPDCCAAT/enhancer-binding protein. (288 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
CTNNB1Catenin beta 1. (781 aa)
JUNDBZIP domain-containing protein. (293 aa)
NOCTNocturnin. (446 aa)
OSTNOsteocrin. (136 aa)
CCN1Cellular communication network factor 1. (368 aa)
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (612 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (881 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (249 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
ZHX3Zinc fingers and homeoboxes 3. (931 aa)
GLI1GLI family zinc finger 1. (1380 aa)
BMP4Bone morphogenetic protein 4. (460 aa)
PDLIM7PDZ and LIM domain 7. (427 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (410 aa)
TP63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (637 aa)
WDR63WD repeat domain 63. (930 aa)
H2ZTF7_LATCHFam20C domain-containing protein. (511 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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