STRINGSTRING
WWTR1 WWTR1 H2ZTF7_LATCH H2ZTF7_LATCH JAG1 JAG1 BMPR1B BMPR1B BMPR1A BMPR1A CEBPB CEBPB ACVR2A ACVR2A LOC102350164 LOC102350164 YAP1 YAP1 FAM20C FAM20C GLI3 GLI3 WWTR1-2 WWTR1-2 ILK ILK CTNNBIP1 CTNNBIP1 SFRP2 SFRP2 SMAD5 SMAD5 LOC102348760 LOC102348760 LOC102351081 LOC102351081 IL6 IL6 IL6ST IL6ST FBXO5 FBXO5 ACVR1 ACVR1 BMP6 BMP6 SMAD1 SMAD1 ACVR2B ACVR2B DDR2 DDR2 H3AXW7_LATCH H3AXW7_LATCH CTHRC1 CTHRC1 BMP2 BMP2 SUCO SUCO CEBPD CEBPD BMPR2 BMPR2 CTNNB1 CTNNB1 JUND JUND CCN1 CCN1 H3BEX6_LATCH H3BEX6_LATCH LRP5 LRP5 ZHX3 ZHX3 BMP4 BMP4 PDLIM7 PDLIM7 TP63 TP63 WDR63 WDR63
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WWTR1WW domain containing transcription regulator 1. (264 aa)
H2ZTF7_LATCHFam20C domain-containing protein. (511 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1220 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
CEBPBCCAAT/enhancer-binding protein. (291 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
LOC102350164Uncharacterized protein. (364 aa)
YAP1Yes associated protein 1. (324 aa)
FAM20CFam20C domain-containing protein. (305 aa)
GLI3GLI family zinc finger 3. (1456 aa)
WWTR1-2WW domain-containing protein. (159 aa)
ILKIntegrin linked kinase. (417 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
SMAD5Mothers against decapentaplegic homolog. (467 aa)
LOC102348760Uncharacterized protein. (782 aa)
LOC102351081Bone morphogenetic protein 16. (396 aa)
IL6Uncharacterized protein. (149 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
FBXO5F-box protein 5. (313 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
BMP6Bone morphogenetic protein 6. (428 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (838 aa)
H3AXW7_LATCHEGF-like domain-containing protein. (204 aa)
CTHRC1Collagen triple helix repeat containing 1. (151 aa)
BMP2Bone morphogenetic protein 2. (402 aa)
SUCOSUN domain containing ossification factor. (1247 aa)
CEBPDCCAAT/enhancer-binding protein. (288 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
CTNNB1Catenin beta 1. (781 aa)
JUNDBZIP domain-containing protein. (293 aa)
CCN1Cellular communication network factor 1. (368 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
ZHX3Zinc fingers and homeoboxes 3. (931 aa)
BMP4Bone morphogenetic protein 4. (460 aa)
PDLIM7PDZ and LIM domain 7. (427 aa)
TP63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (637 aa)
WDR63WD repeat domain 63. (930 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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