STRINGSTRING
F2 F2 DLX2 DLX2 TMEM98 TMEM98 DLX1 DLX1 NKX6-2 NKX6-2 LINGO1 LINGO1 NR1D1 NR1D1 NKX6-1 NKX6-1 CTNNB1 CTNNB1 NR2E1 NR2E1 NF1 NF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
DLX2Distal-less homeobox 2. (278 aa)
TMEM98Transmembrane protein 98. (226 aa)
DLX1Distal-less homeobox 1. (253 aa)
NKX6-2NK6 homeobox 2. (278 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (617 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (614 aa)
NKX6-1NK6 homeobox 1. (316 aa)
CTNNB1Catenin beta 1. (781 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (477 aa)
NF1Neurofibromin 1. (2814 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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