(25 nodes) Positive regulation of glial cell differentiation network (Latimeria chalumnae)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	GSX2	GS homeobox 2. (279 aa)
	NKX6-2	NK6 homeobox 2. (278 aa)
	MAG	Myelin associated glycoprotein. (633 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (403 aa)
	LOC102356309	Uncharacterized protein. (314 aa)
	H3A2T1_LATCH	Uncharacterized protein. (573 aa)
	LOC102356030	Uncharacterized protein. (313 aa)
	H2ZZI1_LATCH	RING-type domain-containing protein. (424 aa)
	PTPRZ1	Protein tyrosine phosphatase receptor type Z1. (2273 aa)
	CLCF1	Cardiotrophin like cytokine factor 1. (235 aa)
	ASPA	Aspartoacylase. (249 aa)
	TNFRSF1B	TNF receptor superfamily member 1B. (465 aa)
	NKX6-1	NK6 homeobox 1. (316 aa)
	LOC102350310	GBP domain-containing protein. (339 aa)
	TP73	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (636 aa)
	MDK	Midkine. (141 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
	MTOR	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
	H3B938_LATCH	Teneurin N-terminal domain-containing protein. (181 aa)
	H3B8U3_LATCH	Serine/threonine-protein kinase TOR. (1418 aa)
	H3B780_LATCH	Uncharacterized protein. (370 aa)
	H3B181_LATCH	Teneurin transmembrane protein 4. (1031 aa)
	PTN	Pleiotrophin. (167 aa)
	H3B6N2_LATCH	Teneurin N-terminal domain-containing protein. (214 aa)
	IL6ST	Interleukin 6 signal transducer. (922 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLCF1	IL6ST	ENSLACP00000001155	ENSLACP00000010218	Cardiotrophin like cytokine factor 1.	Interleukin 6 signal transducer.	0.944
H3B181_LATCH	H3B6N2_LATCH	ENSLACP00000015652	ENSLACP00000017553	Teneurin transmembrane protein 4.	Teneurin N-terminal domain-containing protein.	0.900
H3B181_LATCH	H3B938_LATCH	ENSLACP00000015652	ENSLACP00000018409	Teneurin transmembrane protein 4.	Teneurin N-terminal domain-containing protein.	0.900
H3B6N2_LATCH	H3B181_LATCH	ENSLACP00000017553	ENSLACP00000015652	Teneurin N-terminal domain-containing protein.	Teneurin transmembrane protein 4.	0.900
H3B6N2_LATCH	H3B938_LATCH	ENSLACP00000017553	ENSLACP00000018409	Teneurin N-terminal domain-containing protein.	Teneurin N-terminal domain-containing protein.	0.942
H3B8U3_LATCH	MTOR	ENSLACP00000018314	ENSLACP00000018843	Serine/threonine-protein kinase TOR.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.944
H3B938_LATCH	H3B181_LATCH	ENSLACP00000018409	ENSLACP00000015652	Teneurin N-terminal domain-containing protein.	Teneurin transmembrane protein 4.	0.900
H3B938_LATCH	H3B6N2_LATCH	ENSLACP00000018409	ENSLACP00000017553	Teneurin N-terminal domain-containing protein.	Teneurin N-terminal domain-containing protein.	0.942
IL6ST	CLCF1	ENSLACP00000010218	ENSLACP00000001155	Interleukin 6 signal transducer.	Cardiotrophin like cytokine factor 1.	0.944
MDK	PTN	ENSLACP00000021288	ENSLACP00000017388	Midkine.	Pleiotrophin.	0.739
MDK	PTPRZ1	ENSLACP00000021288	ENSLACP00000002153	Midkine.	Protein tyrosine phosphatase receptor type Z1.	0.728
MTOR	H3B8U3_LATCH	ENSLACP00000018843	ENSLACP00000018314	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.944
PTN	MDK	ENSLACP00000017388	ENSLACP00000021288	Pleiotrophin.	Midkine.	0.739
PTN	PTPRZ1	ENSLACP00000017388	ENSLACP00000002153	Pleiotrophin.	Protein tyrosine phosphatase receptor type Z1.	0.954
PTPRZ1	MDK	ENSLACP00000002153	ENSLACP00000021288	Protein tyrosine phosphatase receptor type Z1.	Midkine.	0.728
PTPRZ1	PTN	ENSLACP00000002153	ENSLACP00000017388	Protein tyrosine phosphatase receptor type Z1.	Pleiotrophin.	0.954