(13 nodes) Negative regulation of gluconeogenesis network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (259 aa)
	FAM3A	Family with sequence similarity 3 member A. (227 aa)
	FAM3C	Family with sequence similarity 3 member C. (134 aa)
	LEPR	Leptin receptor. (1149 aa)
	SIRT6	Sirtuin 6. (375 aa)
	LOC102352539	Uncharacterized protein. (949 aa)
	CRY1	Cryptochrome circadian regulator 1. (653 aa)
	LOC102365364	Cryptochrome circadian regulator 3a. (616 aa)
	H3AWN2_LATCH	Cryptochrome circadian regulator 4. (531 aa)
	LOC102346019	C1q domain-containing protein. (226 aa)
	SOGA1	Suppressor of glucose, autophagy associated 1. (1651 aa)
	C1QTNF12	C1q and TNF related 12. (265 aa)
	MST1	Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (707 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	LEPR	ENSLACP00000000452	ENSLACP00000008593	Adiponectin, C1Q and collagen domain containing.	Leptin receptor.	0.554
ADIPOQ	LOC102346019	ENSLACP00000000452	ENSLACP00000019134	Adiponectin, C1Q and collagen domain containing.	C1q domain-containing protein.	0.904
LEPR	ADIPOQ	ENSLACP00000008593	ENSLACP00000000452	Leptin receptor.	Adiponectin, C1Q and collagen domain containing.	0.554
LEPR	LOC102346019	ENSLACP00000008593	ENSLACP00000019134	Leptin receptor.	C1q domain-containing protein.	0.422
LOC102346019	ADIPOQ	ENSLACP00000019134	ENSLACP00000000452	C1q domain-containing protein.	Adiponectin, C1Q and collagen domain containing.	0.904
LOC102346019	LEPR	ENSLACP00000019134	ENSLACP00000008593	C1q domain-containing protein.	Leptin receptor.	0.422