STRINGSTRING
LOC102356575 LOC102356575 LOC102345793 LOC102345793 CSPP1 CSPP1 KIF14 KIF14 ADAM17 ADAM17 H3AM65_LATCH H3AM65_LATCH CD28 CD28 LOC102357614 LOC102357614 FBXO5 FBXO5 CDC7 CDC7 CDC14B CDC14B SMC4 SMC4 ATRX ATRX TTL TTL STIL STIL CDK5R1 CDK5R1 DUSP3 DUSP3 YTHDC2 YTHDC2 TFDP1 TFDP1 H3ASN6_LATCH H3ASN6_LATCH NUMA1 NUMA1 MECP2 MECP2 KLHL18 KLHL18 RRM2 RRM2 CKS1B CKS1B PAF1 PAF1 H3ATF5_LATCH H3ATF5_LATCH MED1 MED1 NSFL1C NSFL1C MACROH2A1 MACROH2A1 RGCC RGCC SPDYA SPDYA DDR2 DDR2 KIF23 KIF23 MEPCE MEPCE H3AWZ8_LATCH H3AWZ8_LATCH ECT2 ECT2 PSMD10 PSMD10 SASS6 SASS6 CCNK CCNK FOXG1 FOXG1 GIPC2 GIPC2 WIZ WIZ GPSM2 GPSM2 CCND1 CCND1 DBF4 DBF4 LOC102345953 LOC102345953 STXBP4 STXBP4 H3B0I5_LATCH H3B0I5_LATCH MAPK15 MAPK15 DYNC1H1 DYNC1H1 FOSL1 FOSL1 PRDM7 PRDM7 MEIOC MEIOC E2F7 E2F7 CDC14A CDC14A H3B277_LATCH H3B277_LATCH SLC6A4 SLC6A4 FBXO42 FBXO42 GEN1 GEN1 ZPR1 ZPR1 THOC1 THOC1 GIPC3 GIPC3 ANKRD17 ANKRD17 USP19 USP19 FAM83D FAM83D CDC27 CDC27 TBX2 TBX2 TPR TPR SLF1 SLF1 LSM11 LSM11 NR2E1 NR2E1 ROCK2 ROCK2 MTBP MTBP CDC42 CDC42 LSM10 LSM10 KMT2E KMT2E H3B8G4_LATCH H3B8G4_LATCH ANAPC7 ANAPC7 E2F8 E2F8 CCNYL1 CCNYL1 RCC2 RCC2 PLK4 PLK4 STOX1 STOX1 SVIL SVIL CDK5R2 CDK5R2 LOC102350363 LOC102350363 EDN1 EDN1 CHEK1 CHEK1 GIPC1 GIPC1 H3BAV2_LATCH H3BAV2_LATCH ATAD5 ATAD5 PBK PBK CXCR5 CXCR5 MAP10 MAP10 RAD51B RAD51B CDC23 CDC23 CUL3 CUL3 HOXA13 HOXA13 CDC25C CDC25C RANBP1 RANBP1 CCNT1 CCNT1 CCND2 CCND2 TGFA TGFA RACGAP1 RACGAP1 LRP6 LRP6 DRD2 DRD2 MNAT1 MNAT1 CIT CIT ANAPC5 ANAPC5 LRP5 LRP5 UBE2C UBE2C LGMN LGMN GLI1 GLI1 SPDYC SPDYC NCAPG NCAPG RHNO1 RHNO1 CCDC57 CCDC57 CDK1 CDK1 CCPG1 CCPG1 DYNC1LI1 DYNC1LI1 M3XHJ5_LATCH M3XHJ5_LATCH PSRC1 PSRC1 MAD1L1 MAD1L1 RPTOR RPTOR CENPV CENPV CHEK2 CHEK2 RAD51C RAD51C CCNT2 CCNT2 CDC16 CDC16 H2ZSY2_LATCH H2ZSY2_LATCH NCAPH NCAPH LOC102366597 LOC102366597 CDT1 CDT1 PLRG1 PLRG1 NCAPH2 NCAPH2 PIWIL2 PIWIL2 SMPD3 SMPD3 CDC73 CDC73 APP APP H2ZWA0_LATCH H2ZWA0_LATCH FEN1 FEN1 LOC102366946 LOC102366946 NCAPG2 NCAPG2 LOC102367471 LOC102367471 DRD3 DRD3 TRIM32 TRIM32 SMC5 SMC5 AIF1 AIF1 PDGFB PDGFB H3A0V9_LATCH H3A0V9_LATCH CCNY CCNY MAP3K20 MAP3K20 PCID2 PCID2 PPP1R10 PPP1R10 BTC BTC PKD1 PKD1 POLDIP2 POLDIP2 MSX1 MSX1 SLF2 SLF2 CUL4A CUL4A EPGN EPGN LOC102365031 LOC102365031 PKD2 PKD2 IGF2 IGF2 MAD2L1BP MAD2L1BP CUL4B CUL4B RB1 RB1 IL10 IL10 ANAPC11 ANAPC11 PAGR1 PAGR1 LOC102360373 LOC102360373 THOC5 THOC5 DDX11 DDX11 CDCA5 CDCA5 CDC25B CDC25B TBX3 TBX3 FGF8 FGF8 MBLAC1 MBLAC1 LOC102361922 LOC102361922 MAD2L1 MAD2L1 LOC102348760 LOC102348760 LOC102367330 LOC102367330 CKS2 CKS2 H3AGP4_LATCH H3AGP4_LATCH LOC102367082 LOC102367082 RRM1 RRM1 CPSF3 CPSF3 LOC102345131 LOC102345131 UBXN2B UBXN2B INO80 INO80 XRCC3 XRCC3 H3AJV2_LATCH H3AJV2_LATCH CEP120 CEP120 LOC102346566 LOC102346566
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102356575Si:dkey-76k16.5. (260 aa)
LOC102345793Si:dkeyp-92c9.2. (294 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1171 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1644 aa)
ADAM17ADAM metallopeptidase domain 17. (827 aa)
H3AM65_LATCHMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa)
CD28Ig-like domain-containing protein. (202 aa)
LOC102357614Fork-head domain-containing protein. (345 aa)
FBXO5F-box protein 5. (313 aa)
CDC7Cell division cycle 7. (560 aa)
CDC14BCell division cycle 14B. (459 aa)
SMC4Structural maintenance of chromosomes protein. (1297 aa)
ATRXATRX chromatin remodeler. (2488 aa)
TTLTubulin tyrosine ligase. (377 aa)
STILSTIL centriolar assembly protein. (1298 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (306 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
YTHDC2YTH domain containing 2. (1429 aa)
TFDP1Transcription factor. (412 aa)
H3ASN6_LATCHHP domain-containing protein. (111 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2155 aa)
MECP2Methyl-CpG binding protein 2. (459 aa)
KLHL18Kelch like family member 18. (577 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (389 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (81 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (530 aa)
H3ATF5_LATCHCdc6_C domain-containing protein. (525 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa)
NSFL1CNSFL1 cofactor. (370 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (370 aa)
RGCCRegulator of cell cycle. (127 aa)
SPDYASpeedy/RINGO cell cycle regulator family member A. (294 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (838 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (961 aa)
MEPCEMethylphosphate capping enzyme. (437 aa)
H3AWZ8_LATCHUncharacterized protein. (385 aa)
ECT2Epithelial cell transforming 2. (919 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (234 aa)
SASS6SAS-6 centriolar assembly protein. (567 aa)
CCNKCyclin K; Belongs to the cyclin family. (605 aa)
FOXG1Forkhead box G1. (409 aa)
GIPC2GIPC PDZ domain containing family member 2. (327 aa)
WIZWIZ zinc finger. (1428 aa)
GPSM2G protein signaling modulator 2, like. (663 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)
DBF4DBF4 zinc finger. (672 aa)
LOC102345953Cyclin D3; Belongs to the cyclin family. (292 aa)
STXBP4Syntaxin binding protein 4. (703 aa)
H3B0I5_LATCHDBF4-type domain-containing protein. (315 aa)
MAPK15Mitogen-activated protein kinase 15. (572 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4615 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (268 aa)
PRDM7PR/SET domain 7. (233 aa)
MEIOCMeiosis specific with coiled-coil domain. (938 aa)
E2F7Uncharacterized protein. (373 aa)
CDC14AUncharacterized protein. (612 aa)
H3B277_LATCHUncharacterized protein. (4290 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (660 aa)
FBXO42F-box protein 42. (721 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (899 aa)
ZPR1ZPR1 zinc finger. (470 aa)
THOC1THO complex 1. (656 aa)
GIPC3GIPC PDZ domain containing family member 3. (319 aa)
ANKRD17Ankyrin repeat domain 17. (2394 aa)
USP19Ubiquitin specific peptidase 19. (1382 aa)
FAM83DFamily with sequence similarity 83 member D. (587 aa)
CDC27Cell division cycle 27. (833 aa)
TBX2T-box transcription factor 2. (689 aa)
TPRTranslocated promoter region, nuclear basket protein. (2360 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1063 aa)
LSM11LSM11, U7 small nuclear RNA associated. (338 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (477 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1462 aa)
MTBPMDM2 binding protein. (877 aa)
CDC42Cell division cycle 42. (156 aa)
LSM10LSM10, U7 small nuclear RNA associated. (130 aa)
KMT2ELysine methyltransferase 2E. (1846 aa)
H3B8G4_LATCHUncharacterized protein. (110 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
E2F8E2F transcription factor 8. (851 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (343 aa)
RCC2Regulator of chromosome condensation 2. (498 aa)
PLK4Polo like kinase 4. (982 aa)
STOX1Storkhead box 1. (891 aa)
SVILSupervillin. (2196 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (325 aa)
LOC102350363Structural maintenance of chromosomes 2. (656 aa)
EDN1Endothelin 1. (216 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (475 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
H3BAV2_LATCHUncharacterized protein. (105 aa)
ATAD5ATPase family AAA domain containing 5. (1828 aa)
PBKPDZ binding kinase. (336 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (373 aa)
MAP10HPHLAWLY domain-containing protein. (862 aa)
RAD51BRAD51 paralog B. (250 aa)
CDC23Cell division cycle 23. (581 aa)
CUL3Cullin 3; Belongs to the cullin family. (769 aa)
HOXA13Homeobox A13b. (295 aa)
CDC25CCell division cycle 25C. (561 aa)
RANBP1RAN binding protein 1. (216 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (731 aa)
CCND2Cyclin D2, b; Belongs to the cyclin family. (291 aa)
TGFATransforming growth factor alpha. (140 aa)
RACGAP1Rac GTPase activating protein 1. (635 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
DRD2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2066 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
LGMNLegumain. (436 aa)
GLI1GLI family zinc finger 1. (1380 aa)
SPDYCSpeedy/RINGO cell cycle regulator family member C. (312 aa)
NCAPGNon-SMC condensin I complex subunit G. (1067 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (319 aa)
CCDC57Uncharacterized protein. (758 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
CCPG1Cell cycle progression 1. (876 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (502 aa)
M3XHJ5_LATCHUncharacterized protein. (158 aa)
PSRC1GTSE1_N domain-containing protein. (399 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (684 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1334 aa)
CENPVCentromere protein V. (159 aa)
CHEK2Checkpoint kinase 2. (411 aa)
RAD51CRAD51 paralog C. (368 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (750 aa)
CDC16Cell division cycle 16. (545 aa)
H2ZSY2_LATCHUncharacterized protein. (345 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (728 aa)
LOC102366597SMC_N domain-containing protein. (374 aa)
CDT1Chromatin licensing and DNA replication factor 1. (520 aa)
PLRG1Pleiotropic regulator 1. (514 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (617 aa)
PIWIL2Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (954 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (657 aa)
CDC73Cell division cycle 73. (316 aa)
APPAmyloid beta precursor protein. (652 aa)
H2ZWA0_LATCHUncharacterized protein. (591 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (317 aa)
LOC102366946Uncharacterized protein. (358 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1154 aa)
LOC102367471Uncharacterized protein; Belongs to the cyclin family. (292 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (443 aa)
TRIM32Tripartite motif containing 32. (647 aa)
SMC5AAA_23 domain-containing protein. (1096 aa)
AIF1Allograft inflammatory factor 1. (119 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (209 aa)
H3A0V9_LATCHDUF5595 domain-containing protein. (661 aa)
CCNYCyclin Y; Belongs to the cyclin family. (257 aa)
MAP3K20Uncharacterized protein. (792 aa)
PCID2PCI domain containing 2. (452 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (792 aa)
BTCEGF-like domain-containing protein. (177 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4241 aa)
POLDIP2DNA polymerase delta interacting protein 2. (369 aa)
MSX1Msh homeobox 1. (256 aa)
SLF2Uncharacterized protein. (597 aa)
CUL4ACullin 4A; Belongs to the cullin family. (851 aa)
EPGNEpithelial mitogen. (161 aa)
LOC102365031ApaG domain-containing protein. (345 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
IGF2Insulin like growth factor 2. (207 aa)
MAD2L1BPMAD2L1 binding protein. (419 aa)
CUL4BCullin 4B; Belongs to the cullin family. (845 aa)
RB1Uncharacterized protein. (411 aa)
IL10Interleukin 10. (185 aa)
ANAPC11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
PAGR1PAXIP1 associated glutamate rich protein 1. (188 aa)
LOC102360373Fork-head domain-containing protein. (374 aa)
THOC5THO complex 5. (734 aa)
DDX11DEAD/H-box helicase 11. (909 aa)
CDCA5Uncharacterized protein. (133 aa)
CDC25BCell division cycle 25B. (582 aa)
TBX3T-box transcription factor 3. (713 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
MBLAC1Metallo-beta-lactamase domain containing 1. (216 aa)
LOC102361922Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family. (448 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (202 aa)
LOC102348760Uncharacterized protein. (782 aa)
LOC102367330Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (616 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
H3AGP4_LATCHTower domain-containing protein. (1245 aa)
LOC102367082XPGI domain-containing protein. (317 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (689 aa)
LOC102345131Si:ch1073-416j23.1. (581 aa)
UBXN2BUBX domain protein 2B. (298 aa)
INO80INO80 complex ATPase subunit. (1542 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (358 aa)
H3AJV2_LATCHPHD-type domain-containing protein. (679 aa)
CEP120Centrosomal protein 120. (499 aa)
LOC102346566Annexin. (343 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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