(69 nodes) Regulation of receptor-mediated endocytosis network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DAB2	DAB adaptor protein 2. (745 aa)
	LRRTM2	Leucine rich repeat transmembrane neuronal 2. (522 aa)
	NEU2	Neuraminidase 2. (381 aa)
	MAGI2	Uncharacterized protein. (397 aa)
	ATXN2	Ataxin 2. (1085 aa)
	ANKRD13D	Ankyrin repeat domain 13D. (611 aa)
	ATAD1	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (367 aa)
	TBC1D5	TBC1 domain family member 5. (335 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1b. (316 aa)
	LRRTM1	Leucine rich repeat transmembrane neuronal 1. (521 aa)
	DTNBP1	Dystrobrevin binding protein 1. (355 aa)
	SYK	Tyrosine-protein kinase. (616 aa)
	EFNB2	Ephrin B2; Belongs to the ephrin family. (338 aa)
	USH1G	USH1 protein network component sans. (471 aa)
	SMAP1	Small ArfGAP 1. (474 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (672 aa)
	UNC119	Unc-119 lipid binding chaperone. (257 aa)
	H3AM01_LATCH	Integrin beta; Belongs to the integrin beta chain family. (769 aa)
	LOC102346105	ANK_REP_REGION domain-containing protein. (133 aa)
	GSG1L	Uncharacterized protein. (174 aa)
	H3AAW0_LATCH	Tyrosine kinase, non-receptor, 2b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1069 aa)
	SYNJ1	Synaptojanin 1. (1563 aa)
	GSG1	Germ cell associated 1. (303 aa)
	SERPINE1	Serpin family E member 1; Belongs to the serpin family. (403 aa)
	FMR1	Fragile X mental retardation 1. (627 aa)
	LOC102358266	Dickkopf WNT signaling pathway inhibitor 1b. (261 aa)
	H3A6Z2_LATCH	GMP_PDE_delta domain-containing protein. (185 aa)
	H3A6Q3_LATCH	Uncharacterized protein. (123 aa)
	NEU3	Neuraminidase 3. (339 aa)
	DNAJC6	DnaJ heat shock protein family (Hsp40) member C6. (993 aa)
	LOC102352528	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
	H3A0S5_LATCH	Uncharacterized protein. (547 aa)
	BMP2K	BMP2 inducible kinase. (1062 aa)
	LRRC1	Uncharacterized protein. (155 aa)
	LOC102352087	Uncharacterized protein. (314 aa)
	ITGAV	Integrin_alpha2 domain-containing protein. (597 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (259 aa)
	H2ZSB4_LATCH	AAA_lid_3 domain-containing protein. (125 aa)
	PICK1	Protein interacting with PRKCA 1. (409 aa)
	GREM1	Gremlin 1, DAN family BMP antagonist. (189 aa)
	ANKRD13A	Ankyrin repeat domain 13A. (469 aa)
	CLU	Clusterin; Belongs to the clusterin family. (461 aa)
	VTN	Vitronectin b. (492 aa)
	WDR54	WD repeat domain 54. (193 aa)
	RIN3	Ras and Rab interactor 3. (951 aa)
	HIP1	Huntingtin interacting protein 1. (1004 aa)
	RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1. (532 aa)
	AAK1	AP2 associated kinase 1. (954 aa)
	HIP1R	Huntingtin interacting protein 1 related. (1039 aa)
	LOC102354752	VPS9 domain-containing protein. (197 aa)
	H3BE69_LATCH	PID domain-containing protein. (136 aa)
	H3ALU1_LATCH	Uncharacterized protein. (1358 aa)
	SCYL2	SCY1 like pseudokinase 2. (939 aa)
	RSPO1	R-spondin 1. (249 aa)
	LOC102346019	C1q domain-containing protein. (226 aa)
	MKLN1	Muskelin 1. (719 aa)
	LOC102347431	Si:ch211-200p22.4. (504 aa)
	CLUL1	Clusterin; Belongs to the clusterin family. (466 aa)
	H3B853_LATCH	Uncharacterized protein. (433 aa)
	CD63	Tetraspanin. (270 aa)
	TNK1	Uncharacterized protein. (173 aa)
	H3B7R9_LATCH	Uncharacterized protein. (174 aa)
	ANKRD13B	Ankyrin repeat domain 13B. (591 aa)
	PPT1	Palmitoyl-protein thioesterase 1. (303 aa)
	H3B4C9_LATCH	PDZ domain-containing protein. (105 aa)
	DRD4	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	PICALM	Phosphatidylinositol binding clathrin assembly protein. (664 aa)
	C1QTNF9	C1q domain-containing protein. (198 aa)
	SGIP1	SH3 domain GRB2 like endophilin interacting protein 1; Belongs to the adaptor complexes medium subunit family. (644 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAK1	DNAJC6	ENSLACP00000020647	ENSLACP00000004567	AP2 associated kinase 1.	DnaJ heat shock protein family (Hsp40) member C6.	0.852
AAK1	H3B7R9_LATCH	ENSLACP00000020647	ENSLACP00000017940	AP2 associated kinase 1.	Uncharacterized protein.	0.632
AAK1	H3B853_LATCH	ENSLACP00000020647	ENSLACP00000018074	AP2 associated kinase 1.	Uncharacterized protein.	0.632
AAK1	HIP1	ENSLACP00000020647	ENSLACP00000021547	AP2 associated kinase 1.	Huntingtin interacting protein 1.	0.644
AAK1	HIP1R	ENSLACP00000020647	ENSLACP00000020325	AP2 associated kinase 1.	Huntingtin interacting protein 1 related.	0.676
AAK1	LDLRAP1	ENSLACP00000020647	ENSLACP00000013427	AP2 associated kinase 1.	Low density lipoprotein receptor adaptor protein 1b.	0.402
AAK1	LOC102347431	ENSLACP00000020647	ENSLACP00000018456	AP2 associated kinase 1.	Si:ch211-200p22.4.	0.673
AAK1	PICALM	ENSLACP00000020647	ENSLACP00000016446	AP2 associated kinase 1.	Phosphatidylinositol binding clathrin assembly protein.	0.632
AAK1	SGIP1	ENSLACP00000020647	ENSLACP00000014967	AP2 associated kinase 1.	SH3 domain GRB2 like endophilin interacting protein 1; Belongs to the adaptor complexes medium subunit family.	0.557
ADIPOQ	LOC102346019	ENSLACP00000000452	ENSLACP00000019134	Adiponectin, C1Q and collagen domain containing.	C1q domain-containing protein.	0.904
ADIPOQ	SERPINE1	ENSLACP00000000452	ENSLACP00000006192	Adiponectin, C1Q and collagen domain containing.	Serpin family E member 1; Belongs to the serpin family.	0.426
ANKRD13A	LOC102346105	ENSLACP00000007434	ENSLACP00000023509	Ankyrin repeat domain 13A.	ANK_REP_REGION domain-containing protein.	0.900
ATAD1	LOC102354752	ENSLACP00000008272	ENSLACP00000020287	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	VPS9 domain-containing protein.	0.411
ATAD1	RABGEF1	ENSLACP00000008272	ENSLACP00000021436	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	RAB guanine nucleotide exchange factor (GEF) 1.	0.411
ATXN2	DNAJC6	ENSLACP00000014229	ENSLACP00000004567	Ataxin 2.	DnaJ heat shock protein family (Hsp40) member C6.	0.767
ATXN2	FMR1	ENSLACP00000014229	ENSLACP00000006036	Ataxin 2.	Fragile X mental retardation 1.	0.611
ATXN2	SYNJ1	ENSLACP00000014229	ENSLACP00000006685	Ataxin 2.	Synaptojanin 1.	0.703
BMP2K	DNAJC6	ENSLACP00000003124	ENSLACP00000004567	BMP2 inducible kinase.	DnaJ heat shock protein family (Hsp40) member C6.	0.852
BMP2K	H3B7R9_LATCH	ENSLACP00000003124	ENSLACP00000017940	BMP2 inducible kinase.	Uncharacterized protein.	0.613
BMP2K	H3B853_LATCH	ENSLACP00000003124	ENSLACP00000018074	BMP2 inducible kinase.	Uncharacterized protein.	0.613