(10 nodes) Behavioral response to pain network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3A4K7_LATCH	Uncharacterized protein. (368 aa)
	LPAR5	Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	P2RX3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
	NTRK1	Tyrosine-protein kinase receptor. (747 aa)
	H3B8U3_LATCH	Serine/threonine-protein kinase TOR. (1418 aa)
	MTOR	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
	THBS1	Thrombospondin 1. (1170 aa)
	P2RX4	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
	VWA1	Von Willebrand factor A domain containing 1. (511 aa)
	P2RX2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3B8U3_LATCH	MTOR	ENSLACP00000018314	ENSLACP00000018843	Serine/threonine-protein kinase TOR.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.944
MTOR	H3B8U3_LATCH	ENSLACP00000018843	ENSLACP00000018314	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase TOR.	0.944
P2RX2	P2RX3	ENSLACP00000019787	ENSLACP00000004798	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.986
P2RX2	P2RX4	ENSLACP00000019787	ENSLACP00000022710	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.961
P2RX3	P2RX2	ENSLACP00000004798	ENSLACP00000019787	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.986
P2RX3	P2RX4	ENSLACP00000004798	ENSLACP00000022710	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.964
P2RX4	P2RX2	ENSLACP00000022710	ENSLACP00000019787	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.961
P2RX4	P2RX3	ENSLACP00000022710	ENSLACP00000004798	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.964