STRINGSTRING
LOC102358221 LOC102358221 FZD3 FZD3 ARX ARX EDNRB EDNRB NRP2 NRP2 HOXB1 HOXB1 KIF26A KIF26A CTNNB1 CTNNB1 NTRK1 NTRK1 TFAP2E TFAP2E ACKR3 ACKR3 SOX8 SOX8 NF1 NF1 PHACTR4 PHACTR4 TP63 TP63 HLX HLX PHOX2A PHOX2A NAV2 NAV2 GDNF GDNF GBX2 GBX2 EDNRA EDNRA FN1 FN1 SEMA3F SEMA3F PHOX2B PHOX2B RET RET HAND2 HAND2 TFAP2A TFAP2A GATA3 GATA3 TFAP2B TFAP2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102358221G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (439 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (604 aa)
ARXAristaless related homeobox. (455 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (440 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (929 aa)
HOXB1Homeobox B1. (309 aa)
KIF26AKinesin family member 26A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1665 aa)
CTNNB1Catenin beta 1. (781 aa)
NTRK1Tyrosine-protein kinase receptor. (747 aa)
TFAP2ETranscription factor AP-2 epsilon. (439 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (366 aa)
SOX8SRY-box transcription factor 8. (477 aa)
NF1Neurofibromin 1. (2814 aa)
PHACTR4Phosphatase and actin regulator. (702 aa)
TP63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (637 aa)
HLXH2.0 like homeobox. (384 aa)
PHOX2APaired like homeobox 2A. (285 aa)
NAV2Neuron navigator 2a. (1109 aa)
GDNFGlial cell derived neurotrophic factor. (222 aa)
GBX2Gastrulation brain homeobox 2. (344 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
FN1Fibronectin 1. (2295 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (772 aa)
PHOX2BPaired like homeobox 2B. (287 aa)
RETRet proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1090 aa)
HAND2Heart and neural crest derivatives expressed 2. (210 aa)
TFAP2ATranscription factor AP-2 alpha. (438 aa)
GATA3GATA binding protein 3. (447 aa)
TFAP2BTranscription factor AP-2 beta. (460 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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