STRINGSTRING
H2ZSY2_LATCH H2ZSY2_LATCH EIF2B4 EIF2B4 TAF4 TAF4 LOC102360187 LOC102360187 FEM1B FEM1B WDR19 WDR19 LOC102355368 LOC102355368 LOC102364341 LOC102364341 ROR2 ROR2 H2ZVZ2_LATCH H2ZVZ2_LATCH KLHL10 KLHL10 JUNB JUNB PTX3 PTX3 FNDC3A FNDC3A LOC102346204 LOC102346204 FZD4 FZD4 H2ZX83_LATCH H2ZX83_LATCH NSDHL NSDHL H2ZXA8_LATCH H2ZXA8_LATCH CEBPB CEBPB SERPINF1 SERPINF1 PRDX4 PRDX4 LOC102361278 LOC102361278 PTPN6 PTPN6 GATA6 GATA6 MAP3K4 MAP3K4 STK4 STK4 EPAS1 EPAS1 PDGFB PDGFB EOMES EOMES GATA3 GATA3 LOC102354865 LOC102354865 TNC TNC GCM1 GCM1 HSD17B4 HSD17B4 CCDC134 CCDC134 PKD1 PKD1 KIT KIT RDH10 RDH10 TAF10 TAF10 TCF24 TCF24 GJB1 GJB1 TNFAIP6 TNFAIP6 PKD2 PKD2 IGF2 IGF2 TBC1D20 TBC1D20 IMMP2L IMMP2L LOC102350947 LOC102350947 LOC102349073 LOC102349073 SERPINE2 SERPINE2 IL10 IL10 ATM ATM CYP7B1 CYP7B1 INHBA INHBA GAS2 GAS2 LEF1 LEF1 HSD17B2 HSD17B2 TCF21 TCF21 NRIP1 NRIP1 NIPBL NIPBL RHOBTB3 RHOBTB3 WNT7A WNT7A WNT9B WNT9B GDF7 GDF7 GJB2 GJB2 BCL2L2 BCL2L2 BAX BAX FRS2 FRS2 RXFP2 RXFP2 H3AC70_LATCH H3AC70_LATCH SFRP2 SFRP2 DHCR24 DHCR24 VGF VGF FGF8 FGF8 LOC102361473 LOC102361473 NR0B1 NR0B1 SETD2 SETD2 H3AES2_LATCH H3AES2_LATCH TGFBR1 TGFBR1 PLD2-2 PLD2-2 H3AGP4_LATCH H3AGP4_LATCH VASH2 VASH2 HECTD1 HECTD1 SIRT1 SIRT1 PCYT1B PCYT1B H3AHR9_LATCH H3AHR9_LATCH PTGS2 PTGS2 SMAD4 SMAD4 H3AIP7_LATCH H3AIP7_LATCH RSPO3 RSPO3 AMH AMH H3AJF8_LATCH H3AJF8_LATCH EAF2 EAF2 H3AJV2_LATCH H3AJV2_LATCH H3AJW9_LATCH H3AJW9_LATCH GATA1 GATA1 H3AKT4_LATCH H3AKT4_LATCH LHX4 LHX4 TFPT TFPT CYP19A1 CYP19A1 TPPP3 TPPP3 H3AM65_LATCH H3AM65_LATCH MERTK MERTK DAZAP1 DAZAP1 KDR KDR BCL2L1 BCL2L1 LEP LEP EIF2S2 EIF2S2 ATRX ATRX SP3 SP3 NUP107 NUP107 ZFAT ZFAT GJB3 GJB3 SLIT2 SLIT2 BMP6 BMP6 HESX1 HESX1 GREB1L GREB1L LOC102359041 LOC102359041 CITED1 CITED1 LOC102360670 LOC102360670 SCAPER SCAPER LHCGR LHCGR STK11 STK11 NDP NDP MED1 MED1 PCDH12 PCDH12 TIFAB TIFAB MDFI MDFI ZNF830 ZNF830 H3AV94_LATCH H3AV94_LATCH FANCA FANCA EIF2B5 EIF2B5 LGR4 LGR4 KDM5B KDM5B SGPL1 SGPL1 FST FST CDX4 CDX4 ING2 ING2 ASB1 ASB1 CRKL CRKL DMRT1 DMRT1 TFEB TFEB BMP15 BMP15 LOC102355583 LOC102355583 ALKBH1 ALKBH1 BPTF BPTF FOSL1 FOSL1 GHSR GHSR GHRL GHRL MYOCD MYOCD E2F7 E2F7 MAS1 MAS1 H3B277_LATCH H3B277_LATCH UBE3A UBE3A TTPAL TTPAL TMF1 TMF1 GREB1 GREB1 DLX3 DLX3 PRDX3 PRDX3 VASH1 VASH1 PHLDA2 PHLDA2 H3B4Z7_LATCH H3B4Z7_LATCH AR AR H3B5A0_LATCH H3B5A0_LATCH H3B5C9_LATCH H3B5C9_LATCH BMPR2 BMPR2 CTNNB1 CTNNB1 ADAM19 ADAM19 PTN PTN LOC102366872 LOC102366872 HOXB13 HOXB13 H3B780_LATCH H3B780_LATCH PPARD PPARD BIRC6 BIRC6 WNT2 WNT2 BAK1 BAK1 PLK4 PLK4 GPR149 GPR149 WT1 WT1 LOC102362765 LOC102362765 SOX8 SOX8 CDX2 CDX2 TFAP2C TFAP2C LOC102349421 LOC102349421 LHX3 LHX3 TMED2 TMED2 H3BCG1_LATCH H3BCG1_LATCH SOCS3 SOCS3 HOXA9 HOXA9 HOXA10 HOXA10 HOXA13 HOXA13 BMP7 BMP7 LOC102348948 LOC102348948 LOC102349393 LOC102349393 LOC102354477 LOC102354477 HNF1A HNF1A AXL AXL H3BEX6_LATCH H3BEX6_LATCH WNT2B WNT2B ST14 ST14 EIF2B2 EIF2B2 SF1 SF1 WDR77 WDR77 HAND1 HAND1 ARID4A ARID4A PRDM1 PRDM1 LOC102358988 LOC102358988 TEX11 TEX11 M3XHJ5_LATCH M3XHJ5_LATCH TP63 TP63 KIF18A KIF18A DMC1 DMC1 SRD5A1 SRD5A1 MAMLD1 MAMLD1 VDR VDR HSD17B3 HSD17B3 SPO11 SPO11 SLIT3 SLIT3 M3XL62_LATCH M3XL62_LATCH SRD5A2 SRD5A2 MSH4 MSH4 STOX2 STOX2 STRA6 STRA6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2ZSY2_LATCHUncharacterized protein. (345 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (533 aa)
TAF4TATA-box binding protein associated factor 4. (830 aa)
LOC102360187MutS homolog 2 (E. coli). (447 aa)
FEM1BFem-1 homolog B. (667 aa)
WDR19WD repeat domain 19. (895 aa)
LOC102355368NR LBD domain-containing protein. (170 aa)
LOC102364341Uncharacterized protein. (271 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (882 aa)
H2ZVZ2_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein. (340 aa)
KLHL10Kelch like family member 10. (606 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (311 aa)
PTX3Uncharacterized protein. (423 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
LOC102346204Protein kinase domain-containing protein. (227 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (530 aa)
H2ZX83_LATCHMutS homolog 2 (E. coli). (360 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (340 aa)
H2ZXA8_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein. (339 aa)
CEBPBCCAAT/enhancer-binding protein. (291 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (420 aa)
PRDX4Peroxiredoxin 4. (269 aa)
LOC102361278Si:dkey-219c3.2. (1070 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (338 aa)
GATA6GATA binding protein 6. (503 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1425 aa)
STK4Serine/threonine kinase 4. (488 aa)
EPAS1Endothelial PAS domain protein 1. (861 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (209 aa)
EOMESEomesodermin. (419 aa)
GATA3GATA binding protein 3. (447 aa)
LOC102354865Uncharacterized protein. (746 aa)
TNCTenascin C. (2213 aa)
GCM1Glial cells missing transcription factor 1. (443 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (740 aa)
CCDC134Coiled-coil domain containing 134. (243 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4241 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (937 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (348 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (142 aa)
TCF24Transcription factor 24. (187 aa)
GJB1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (276 aa)
TNFAIP6TNF alpha induced protein 6. (279 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
IGF2Insulin like growth factor 2. (207 aa)
TBC1D20TBC1 domain family member 20. (396 aa)
IMMP2LInner mitochondrial membrane peptidase subunit 2. (111 aa)
LOC102350947G_PROTEIN_RECEP_F1_2 domain-containing protein. (327 aa)
LOC102349073Zgc:63863. (409 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (403 aa)
IL10Interleukin 10. (185 aa)
ATMATM serine/threonine kinase. (2375 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (480 aa)
INHBAInhibin subunit beta A. (390 aa)
GAS2Growth arrest specific 2. (322 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (298 aa)
TCF21Transcription factor 21. (179 aa)
NRIP1Nuclear receptor interacting protein 1. (1186 aa)
NIPBLNipped-B protein. (2707 aa)
RHOBTB3Rho related BTB domain containing 3. (608 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
GDF7Growth differentiation factor 7. (416 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (211 aa)
BCL2L2BCL2 like 2. (189 aa)
BAXUncharacterized protein. (223 aa)
FRS2Fibroblast growth factor receptor substrate 2. (502 aa)
RXFP2Relaxin family peptide receptor 2. (763 aa)
H3AC70_LATCHLRRNT domain-containing protein. (132 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
DHCR2424-dehydrocholesterol reductase. (516 aa)
VGFVGF nerve growth factor inducible. (438 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC102361473Uncharacterized protein. (1211 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (261 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2541 aa)
H3AES2_LATCHUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (354 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
PLD2-2Uncharacterized protein. (392 aa)
H3AGP4_LATCHTower domain-containing protein. (1245 aa)
VASH2Vasohibin 2. (370 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2580 aa)
SIRT1Sirtuin 1. (729 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (369 aa)
H3AHR9_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (336 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (620 aa)
SMAD4MH2 domain-containing protein. (412 aa)
H3AIP7_LATCHUncharacterized protein. (925 aa)
RSPO3R-spondin 3. (213 aa)
AMHAnti-Mullerian hormone. (562 aa)
H3AJF8_LATCHPeptidase S1 domain-containing protein. (483 aa)
EAF2ELL associated factor 2. (257 aa)
H3AJV2_LATCHPHD-type domain-containing protein. (679 aa)
H3AJW9_LATCHUncharacterized protein. (113 aa)
GATA1GATA binding protein 1b. (432 aa)
H3AKT4_LATCHUncharacterized protein. (128 aa)
LHX4LIM homeobox 4. (312 aa)
TFPTTCF3 (E2A) fusion partner. (254 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1. (443 aa)
TPPP3Tubulin polymerization-promoting protein family member 3. (187 aa)
H3AM65_LATCHMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa)
MERTKMER proto-oncogene, tyrosine kinase. (897 aa)
DAZAP1DAZ associated protein 1. (440 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
BCL2L1BCL2 like 1. (239 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
EIF2S2Eukaryotic translation initiation factor 2 subunit beta. (335 aa)
ATRXATRX chromatin remodeler. (2488 aa)
SP3Sp3 transcription factor. (785 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (930 aa)
ZFATZinc finger and AT-hook domain containing. (1090 aa)
GJB3Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (270 aa)
SLIT2Slit guidance ligand 2. (1372 aa)
BMP6Bone morphogenetic protein 6. (428 aa)
HESX1HESX homeobox 1. (185 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1842 aa)
LOC102359041Zgc:153993. (208 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (165 aa)
LOC102360670Uncharacterized protein. (209 aa)
SCAPERS-phase cyclin A associated protein in the ER. (1476 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (593 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
NDPCTCK domain-containing protein. (132 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa)
PCDH12Protocadherin 12. (1146 aa)
TIFABTIFA inhibitor. (149 aa)
MDFIMyoD family inhibitor. (156 aa)
ZNF830zf-C2H2_jaz domain-containing protein. (240 aa)
H3AV94_LATCHFip1 domain-containing protein. (504 aa)
FANCAFA complementation group A. (1436 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (718 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (955 aa)
KDM5BLysine demethylase 5B. (1659 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (566 aa)
FSTFollistatin. (319 aa)
CDX4Caudal type homeobox 4. (268 aa)
ING2Inhibitor of growth protein. (269 aa)
ASB1Ankyrin repeat and SOCS box containing 1. (363 aa)
CRKLCRK like proto-oncogene, adaptor protein. (219 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (370 aa)
TFEBTranscription factor EB. (459 aa)
BMP15Bone morphogenetic protein 15. (394 aa)
LOC102355583Uncharacterized protein. (80 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (373 aa)
BPTFBromodomain PHD finger transcription factor. (3013 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (268 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (367 aa)
GHRLMotilin_assoc domain-containing protein. (110 aa)
MYOCDMyocardin. (963 aa)
E2F7Uncharacterized protein. (373 aa)
MAS1G_PROTEIN_RECEP_F1_2 domain-containing protein. (309 aa)
H3B277_LATCHUncharacterized protein. (4290 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (907 aa)
TTPALAlpha tocopherol transfer protein like. (340 aa)
TMF1TATA element modulatory factor 1. (1135 aa)
GREB1Uncharacterized protein. (1948 aa)
DLX3Distal-less homeobox 3. (282 aa)
PRDX3Peroxiredoxin 3. (254 aa)
VASH1Vasohibin 1. (363 aa)
PHLDA2Pleckstrin homology like domain family A member 2. (137 aa)
H3B4Z7_LATCHUncharacterized protein; Belongs to the cullin family. (1385 aa)
ARAndrogen receptor. (412 aa)
H3B5A0_LATCHFibronectin type-III domain-containing protein. (467 aa)
H3B5C9_LATCHProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
CTNNB1Catenin beta 1. (781 aa)
ADAM19ADAM metallopeptidase domain 19. (765 aa)
PTNPleiotrophin. (167 aa)
LOC102366872TIR domain-containing protein; Belongs to the Toll-like receptor family. (862 aa)
HOXB13Homeobox B13. (306 aa)
H3B780_LATCHUncharacterized protein. (370 aa)
PPARDPeroxisome proliferator activated receptor delta. (396 aa)
BIRC6Baculoviral IAP repeat containing 6. (4819 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
PLK4Polo like kinase 4. (982 aa)
GPR149G protein-coupled receptor 149. (714 aa)
WT1WT1 transcription factor. (422 aa)
LOC102362765Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (537 aa)
SOX8SRY-box transcription factor 8. (477 aa)
CDX2Caudal type homeobox 2. (258 aa)
TFAP2CTranscription factor AP-2 gamma. (446 aa)
LOC102349421Cytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (528 aa)
LHX3LIM homeobox 3. (313 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
H3BCG1_LATCHSET domain-containing protein. (714 aa)
SOCS3Suppressor of cytokine signaling 3. (205 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (261 aa)
HOXA10Homeobox A10. (557 aa)
HOXA13Homeobox A13b. (295 aa)
BMP7Bone morphogenetic protein 7. (425 aa)
LOC102348948IF rod domain-containing protein; Belongs to the intermediate filament family. (548 aa)
LOC102349393IF rod domain-containing protein; Belongs to the intermediate filament family. (514 aa)
LOC102354477Uncharacterized protein. (838 aa)
HNF1AHNF1 homeobox A. (624 aa)
AXLAXL receptor tyrosine kinase. (872 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. (845 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (400 aa)
SF1Splicing factor 1. (547 aa)
WDR77WD repeat domain 77. (322 aa)
HAND1Heart and neural crest derivatives expressed 1. (196 aa)
ARID4AAT-rich interaction domain 4A. (1297 aa)
PRDM1SET domain-containing protein. (176 aa)
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
TEX11Testis expressed 11. (916 aa)
M3XHJ5_LATCHUncharacterized protein. (158 aa)
TP63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (637 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (962 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (317 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (261 aa)
MAMLD1Mastermind like domain containing 1. (958 aa)
VDRVitamin D receptor. (427 aa)
HSD17B3Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (394 aa)
SLIT3Slit guidance ligand 3. (635 aa)
M3XL62_LATCHUncharacterized protein. (269 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (254 aa)
MSH4DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (955 aa)
STOX2Storkhead box 2. (935 aa)
STRA6Stimulated by retinoic acid 6. (664 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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