STRINGSTRING
HOXD11 HOXD11 HOXD10 HOXD10 HOXD9 HOXD9 PDGFRA PDGFRA LOC102357376 LOC102357376 PEX7 PEX7 EIF4A3 EIF4A3 FREM1 FREM1 IFT140 IFT140 CCN2 CCN2 GAS1 GAS1 TCF15 TCF15 WDR19 WDR19 H2ZUZ2_LATCH H2ZUZ2_LATCH RYK RYK DLX2 DLX2 SP5 SP5 LOC102354258 LOC102354258 DLX5 DLX5 IMPAD1 IMPAD1 TMEM107 TMEM107 CER1 CER1 NKX3-2 NKX3-2 GLI3 GLI3 PKD1 PKD1 TGFBR2 TGFBR2 MSX1 MSX1 RAB23 RAB23 RDH10 RDH10 NLE1 NLE1 INPPL1 INPPL1 NIPBL NIPBL GSC GSC OSR2 OSR2 WNT9B WNT9B LOC102356182 LOC102356182 OSR1 OSR1 SLC39A1 SLC39A1 PCGF2 PCGF2 RARA RARA RARB RARB ZMPSTE24 ZMPSTE24 SERPINH1 SERPINH1 FGF8 FGF8 SETD2 SETD2 TGFBR1 TGFBR1 SMAD2 SMAD2 OTOR OTOR MEF2D MEF2D LOC106703556 LOC106703556 THBS3 THBS3 LOC102364365 LOC102364365 HOXD3 HOXD3 S1PR2 S1PR2 HOXD4 HOXD4 PHOSPHO1 PHOSPHO1 LOC102349503 LOC102349503 HOXD8 HOXD8 MMP14 MMP14 EXT2 EXT2 SOX5 SOX5 TRIP11 TRIP11 NAB2 NAB2 LRP5 LRP5 SIX1 SIX1 SIX4 SIX4 ALX3 ALX3 FGF6 FGF6 H3BEX6_LATCH H3BEX6_LATCH BARX2 BARX2 SOX6 SOX6 HOXA9 HOXA9 HOXA5 HOXA5 HOXA3 HOXA3 HOXA2 HOXA2 FUZ FUZ ANXA6 ANXA6 HOXC11 HOXC11 HOXC9 HOXC9 HOXC8 HOXC8 HOXC4 HOXC4 RARG RARG FOXN3 FOXN3 CYP26B1 CYP26B1 CTNNB1 CTNNB1 HOXB9 HOXB9 BMPR2 BMPR2 HOXB8 HOXB8 HOXB7 HOXB7 HOXB6 HOXB6 WWOX WWOX HOXB4 HOXB4 HOXB3 HOXB3 HOXB2 HOXB2 HOXB1 HOXB1 HHIP HHIP SCX SCX H3B277_LATCH H3B277_LATCH SIX2 SIX2 PHOSPHO2 PHOSPHO2 FGF18 FGF18 RAB33B RAB33B LOC102347076 LOC102347076 LOC102351582 LOC102351582 ZEB1 ZEB1 LOC102362405 LOC102362405 MMP13 MMP13 ALCAM ALCAM LOC102352693 LOC102352693 FGF4 FGF4 SGPL1 SGPL1 ATG9A ATG9A CHST11 CHST11 MDFI MDFI TIFAB TIFAB PSEN1 PSEN1 PPARGC1B PPARGC1B BMP6 BMP6 IFT80 IFT80 SMAD3 SMAD3 DHRS3 DHRS3 BMI1 BMI1 ANKRD11 ANKRD11 ZFAND5 ZFAND5 UNCX UNCX PAX1 PAX1 ATG9B ATG9B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXD11Homeobox D11. (294 aa)
HOXD10Homeobox D10. (337 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (268 aa)
PDGFRAUncharacterized protein. (1094 aa)
LOC102357376CSRNP_N domain-containing protein. (152 aa)
PEX7Peroxisomal biogenesis factor 7. (140 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (406 aa)
FREM1FRAS1 related extracellular matrix 1. (2091 aa)
IFT140Intraflagellar transport 140. (1471 aa)
CCN2Cellular communication network factor 2. (344 aa)
GAS1Growth arrest specific 1. (259 aa)
TCF15Transcription factor 15. (163 aa)
WDR19WD repeat domain 19. (895 aa)
H2ZUZ2_LATCHUncharacterized protein. (1044 aa)
RYKReceptor like tyrosine kinase. (542 aa)
DLX2Distal-less homeobox 2. (278 aa)
SP5Sp5 transcription factor. (372 aa)
LOC102354258Si:ch211-246m6.4. (181 aa)
DLX5Distal-less homeobox 5. (290 aa)
IMPAD1Inositol monophosphatase domain containing 1. (350 aa)
TMEM107Transmembrane protein 107. (140 aa)
CER1CTCK domain-containing protein. (257 aa)
NKX3-2NK3 homeobox 2. (282 aa)
GLI3GLI family zinc finger 3. (1456 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4241 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
MSX1Msh homeobox 1. (256 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (348 aa)
NLE1Notchless homolog 1. (488 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1220 aa)
NIPBLNipped-B protein. (2707 aa)
GSCGoosecoid homeobox. (243 aa)
OSR2Odd-skipped related transciption factor 2. (314 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
LOC102356182Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
OSR1Odd-skipped related transcription factor 1. (259 aa)
SLC39A1Solute carrier family 39 member 1. (340 aa)
PCGF2Polycomb group ring finger 2. (340 aa)
RARARetinoic acid receptor alpha. (505 aa)
RARBNR LBD domain-containing protein. (299 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (453 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (405 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2541 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
OTOROtoraplin. (128 aa)
MEF2DMyocyte enhancer factor 2D. (486 aa)
LOC106703556Natriuretic peptide A-like. (129 aa)
THBS3Thrombospondin 3. (930 aa)
LOC102364365Natriuretic peptide A-like. (130 aa)
HOXD3Homeobox D3. (419 aa)
S1PR2Sphingosine-1-phosphate receptor 2. (352 aa)
HOXD4Homeobox D4a. (251 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
LOC102349503Uncharacterized protein. (300 aa)
HOXD8Homeobox domain-containing protein. (234 aa)
MMP14Matrix metallopeptidase 14. (597 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (718 aa)
SOX5SRY-box transcription factor 5. (757 aa)
TRIP11Thyroid hormone receptor interactor 11. (1997 aa)
NAB2NGFI-A binding protein 2. (482 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
SIX1SIX homeobox 1. (283 aa)
SIX4SIX homeobox 4. (742 aa)
ALX3ALX homeobox 3. (257 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
BARX2BARX homeobox 2. (277 aa)
SOX6SRY-box transcription factor 6. (814 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (261 aa)
HOXA5Homeobox A5. (269 aa)
HOXA3Homeobox A3. (411 aa)
HOXA2Homeobox A2b. (366 aa)
FUZFuzzy planar cell polarity protein. (426 aa)
ANXA6Annexin. (662 aa)
HOXC11Homeobox C11. (301 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (264 aa)
HOXC8Homeobox C8. (132 aa)
HOXC4Homeobox C4. (439 aa)
RARGRetinoic acid receptor gamma. (389 aa)
FOXN3Forkhead box N3. (484 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa)
CTNNB1Catenin beta 1. (781 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (247 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
HOXB8Homeobox B8. (247 aa)
HOXB7Homeobox B7. (216 aa)
HOXB6Homeobox B6. (361 aa)
WWOXWW domain containing oxidoreductase. (353 aa)
HOXB4Homeobox domain-containing protein. (247 aa)
HOXB3Homeobox B3. (404 aa)
HOXB2Homeobox B2. (362 aa)
HOXB1Homeobox B1. (309 aa)
HHIPHedgehog interacting protein. (687 aa)
SCXScleraxis bHLH transcription factor. (182 aa)
H3B277_LATCHUncharacterized protein. (4290 aa)
SIX2SIX homeobox 2. (289 aa)
PHOSPHO2Phosphatase, orphan 2. (243 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
RAB33BRAB33B, member RAS oncogene family. (230 aa)
LOC102347076Uncharacterized protein. (232 aa)
LOC102351582SH2 domain-containing protein. (892 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1076 aa)
LOC102362405Homeobox domain-containing protein. (954 aa)
MMP13Matrix metallopeptidase 13. (467 aa)
ALCAMActivated leukocyte cell adhesion molecule. (530 aa)
LOC102352693Fras1 related extracellular matrix 1b. (2189 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (566 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (854 aa)
CHST11Carbohydrate sulfotransferase. (298 aa)
MDFIMyoD family inhibitor. (156 aa)
TIFABTIFA inhibitor. (149 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
PPARGC1BPPARG coactivator 1 beta. (986 aa)
BMP6Bone morphogenetic protein 6. (428 aa)
IFT80Intraflagellar transport 80. (780 aa)
SMAD3Mothers against decapentaplegic homolog. (358 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (303 aa)
BMI1Bmi1 polycomb ring finger oncogene 1b. (326 aa)
ANKRD11Ankyrin repeat domain 11. (2717 aa)
ZFAND5Zinc finger AN1-type containing 5. (215 aa)
UNCXUNC homeobox. (498 aa)
PAX1Paired box 1. (362 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (801 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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