STRINGSTRING
MMP14 MMP14 FUZ FUZ SULF1 SULF1 EIF4A3 EIF4A3 KIAA1217 KIAA1217 IFT140 IFT140 GAS1 GAS1 WDR19 WDR19 H2ZUZ2_LATCH H2ZUZ2_LATCH DLX2 DLX2 DLX1 DLX1 NKX3-2 NKX3-2 GLI3 GLI3 TGFBR2 TGFBR2 RDH10 RDH10 HAND2 HAND2 NIPBL NIPBL GSC GSC EDNRA EDNRA OSR2 OSR2 WNT9B WNT9B OSR1 OSR1 SLC39A1 SLC39A1 WNT11 WNT11 PCGF2 PCGF2 FGF8 FGF8 SETD2 SETD2 TGFBR1 TGFBR1 SMAD2 SMAD2 TAPT1 TAPT1 HOXD1 HOXD1 SULF2 SULF2 HOXD3 HOXD3 S1PR2 S1PR2 HOXD4 HOXD4 SLC2A10 SLC2A10 PDGFRA PDGFRA HOXD9 HOXD9 HOXD10 HOXD10 HOXD11 HOXD11 BMI1 BMI1 SP3 SP3 SMAD3 SMAD3 DMRT2 DMRT2 MDFI MDFI CHST11 CHST11 ALCAM ALCAM LOC102362405 LOC102362405 ZEB1 ZEB1 SIX2 SIX2 DEAF1 DEAF1 HOXB1 HOXB1 HOXB2 HOXB2 HOXB3 HOXB3 HOXB4 HOXB4 HOXB6 HOXB6 HOXB7 HOXB7 HOXB9 HOXB9 CTNNB1 CTNNB1 HOXC4 HOXC4 HOXC6 HOXC6 HOXC9 HOXC9 HOXC11 HOXC11 WNT9A WNT9A HOXA1 HOXA1 HOXA2 HOXA2 HOXA3 HOXA3 HOXA5 HOXA5 HOXA6 HOXA6 HOXA9 HOXA9 ALX3 ALX3 SIX4 SIX4 SIX1 SIX1 MKS1 MKS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMP14Matrix metallopeptidase 14. (597 aa)
FUZFuzzy planar cell polarity protein. (426 aa)
SULF1Sulfatase 1. (1129 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (406 aa)
KIAA1217KIAA1217. (1678 aa)
IFT140Intraflagellar transport 140. (1471 aa)
GAS1Growth arrest specific 1. (259 aa)
WDR19WD repeat domain 19. (895 aa)
H2ZUZ2_LATCHUncharacterized protein. (1044 aa)
DLX2Distal-less homeobox 2. (278 aa)
DLX1Distal-less homeobox 1. (253 aa)
NKX3-2NK3 homeobox 2. (282 aa)
GLI3GLI family zinc finger 3. (1456 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (348 aa)
HAND2Heart and neural crest derivatives expressed 2. (210 aa)
NIPBLNipped-B protein. (2707 aa)
GSCGoosecoid homeobox. (243 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
OSR2Odd-skipped related transciption factor 2. (314 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
OSR1Odd-skipped related transcription factor 1. (259 aa)
SLC39A1Solute carrier family 39 member 1. (340 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PCGF2Polycomb group ring finger 2. (340 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2541 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TAPT1Transmembrane anterior posterior transformation 1. (597 aa)
HOXD1Homeobox D1. (312 aa)
SULF2Extracellular sulfatase. (877 aa)
HOXD3Homeobox D3. (419 aa)
S1PR2Sphingosine-1-phosphate receptor 2. (352 aa)
HOXD4Homeobox D4a. (251 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (535 aa)
PDGFRAUncharacterized protein. (1094 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (268 aa)
HOXD10Homeobox D10. (337 aa)
HOXD11Homeobox D11. (294 aa)
BMI1Bmi1 polycomb ring finger oncogene 1b. (326 aa)
SP3Sp3 transcription factor. (785 aa)
SMAD3Mothers against decapentaplegic homolog. (358 aa)
DMRT2Doublesex and mab-3 related transcription factor 2. (501 aa)
MDFIMyoD family inhibitor. (156 aa)
CHST11Carbohydrate sulfotransferase. (298 aa)
ALCAMActivated leukocyte cell adhesion molecule. (530 aa)
LOC102362405Homeobox domain-containing protein. (954 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1076 aa)
SIX2SIX homeobox 2. (289 aa)
DEAF1DEAF1 transcription factor. (565 aa)
HOXB1Homeobox B1. (309 aa)
HOXB2Homeobox B2. (362 aa)
HOXB3Homeobox B3. (404 aa)
HOXB4Homeobox domain-containing protein. (247 aa)
HOXB6Homeobox B6. (361 aa)
HOXB7Homeobox B7. (216 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (247 aa)
CTNNB1Catenin beta 1. (781 aa)
HOXC4Homeobox C4. (439 aa)
HOXC6Homeobox C6. (233 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (264 aa)
HOXC11Homeobox C11. (301 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
HOXA1Homeobox A1. (327 aa)
HOXA2Homeobox A2b. (366 aa)
HOXA3Homeobox A3. (411 aa)
HOXA5Homeobox A5. (269 aa)
HOXA6Homeobox A6. (230 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (261 aa)
ALX3ALX homeobox 3. (257 aa)
SIX4SIX homeobox 4. (742 aa)
SIX1SIX homeobox 1. (283 aa)
MKS1MKS transition zone complex subunit 1. (561 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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