STRINGSTRING
TGFB3 TGFB3 M3XLI6_LATCH M3XLI6_LATCH PLG PLG LOC102348329 LOC102348329 ELF3 ELF3 VDR VDR ACVRL1 ACVRL1 CRB2 CRB2 LRP5 LRP5 TGFB1 TGFB1 H3BEX6_LATCH H3BEX6_LATCH AXL AXL LRRK1 LRRK1 LOC102354477 LOC102354477 HOXA3 HOXA3 BAK1 BAK1 NCDN NCDN PTN PTN CTNNB1 CTNNB1 BMPR2 BMPR2 CSPG4 CSPG4 SNX10 SNX10 CTHRC1 CTHRC1 ATG5 ATG5 EFNA2 EFNA2 TPH1 TPH1 DLL4 DLL4 LGR4 LGR4 EPHA2 EPHA2 NOX4 NOX4 RSPO3 RSPO3 SEMA3C SEMA3C TNFSF11 TNFSF11 WNT16 WNT16 IGFBP5 IGFBP5 TPP1 TPP1 FGF8 FGF8 DBH DBH TIE1 TIE1 BAX BAX CRB1 CRB1 LOC102347832 LOC102347832 EDNRA EDNRA TRAF6 TRAF6 BSX BSX EPAS1 EPAS1 LOC102356587 LOC102356587 ACP5 ACP5 JAG1 JAG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
M3XLI6_LATCHUncharacterized protein. (426 aa)
PLGPlasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
LOC102348329Secreted phosphoprotein 2. (184 aa)
ELF3E74 like ETS transcription factor 3. (385 aa)
VDRVitamin D receptor. (427 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (497 aa)
CRB2Uncharacterized protein. (1473 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
AXLAXL receptor tyrosine kinase. (872 aa)
LRRK1Leucine rich repeat kinase 1. (1987 aa)
LOC102354477Uncharacterized protein. (838 aa)
HOXA3Homeobox A3. (411 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
NCDNNeurochondrin. (683 aa)
PTNPleiotrophin. (167 aa)
CTNNB1Catenin beta 1. (781 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2343 aa)
SNX10Sorting nexin 10. (203 aa)
CTHRC1Collagen triple helix repeat containing 1. (151 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (139 aa)
TPH1Tryptophan hydroxylase 1. (482 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (688 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (955 aa)
EPHA2Uncharacterized protein. (979 aa)
NOX4NADPH oxidase 4. (541 aa)
RSPO3R-spondin 3. (213 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (550 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (169 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
IGFBP5Insulin like growth factor binding protein 5. (279 aa)
TPP1Tripeptidyl peptidase 1. (569 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
DBHDopamine beta-hydroxylase. (617 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1143 aa)
BAXUncharacterized protein. (223 aa)
CRB1Crumbs cell polarity complex component 1. (1366 aa)
LOC102347832Si:dkey-193c22.2. (2393 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
BSXBrain-specific homeobox. (249 aa)
EPAS1Endothelial PAS domain protein 1. (861 aa)
LOC102356587Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (628 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (329 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1220 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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